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Application of metal nanoparticle–hydrogel composites in tissue regeneration

Challenges in organ transplantation such as high organ demand and biocompatibility issues have led scientists in the field of tissue engineering and regenerative medicine to work on the use of scaffolds as an alternative to transplantation. Among different types of scaffolds, polymeric hydrogel scaf...

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Main Authors: Tan, Hui Li, Teow, Sin Yeang *, Pushpamalar, Janarthanan
Format: Article
Language:English
Published: MDPI 2019
Subjects:
QH301 Biology
R Medicine (General)
Online Access:http://eprints.sunway.edu.my/1150/1/Teow%20Sin%20Yeang%20Application%20of%20metal%20NP.pdf
http://eprints.sunway.edu.my/1150/
http://doi.org/10.3390/bioengineering6010017
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spelling my.sunway.eprints.11502019-11-28T01:32:09Z http://eprints.sunway.edu.my/1150/ Application of metal nanoparticle–hydrogel composites in tissue regeneration Tan, Hui Li Teow, Sin Yeang * Pushpamalar, Janarthanan QH301 Biology R Medicine (General) Challenges in organ transplantation such as high organ demand and biocompatibility issues have led scientists in the field of tissue engineering and regenerative medicine to work on the use of scaffolds as an alternative to transplantation. Among different types of scaffolds, polymeric hydrogel scaffolds have received considerable attention because of their biocompatibility and structural similarity to native tissues. However, hydrogel scaffolds have several limitations, such as weak mechanical property and a lack of bioactive property. On the other hand, noble metal particles, particularly gold (Au) and silver (Ag) nanoparticles (NPs), can be incorporated into the hydrogel matrix to form NP–hydrogel composite scaffolds with enhanced physical and biological properties. This review aims to highlight the potential of these hybrid materials in tissue engineering applications. Additionally, the main approaches that have been used for the synthesis of NP–hydrogel composites and the possible limitations and challenges associated with the application of these materials are discussed MDPI 2019-02-11 Article PeerReviewed text en cc_by_nc_4 http://eprints.sunway.edu.my/1150/1/Teow%20Sin%20Yeang%20Application%20of%20metal%20NP.pdf Tan, Hui Li and Teow, Sin Yeang * and Pushpamalar, Janarthanan (2019) Application of metal nanoparticle–hydrogel composites in tissue regeneration. Bioengineering, 6 (1). p. 17. ISSN 2306-5354 http://doi.org/10.3390/bioengineering6010017 doi:10.3390/bioengineering6010017
institution Sunway University
building Sunway Campus Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Sunway University
content_source Sunway Institutional Repository
url_provider http://eprints.sunway.edu.my/
language English
topic QH301 Biology
R Medicine (General)
spellingShingle QH301 Biology
R Medicine (General)
Tan, Hui Li
Teow, Sin Yeang *
Pushpamalar, Janarthanan
Application of metal nanoparticle–hydrogel composites in tissue regeneration
description Challenges in organ transplantation such as high organ demand and biocompatibility issues have led scientists in the field of tissue engineering and regenerative medicine to work on the use of scaffolds as an alternative to transplantation. Among different types of scaffolds, polymeric hydrogel scaffolds have received considerable attention because of their biocompatibility and structural similarity to native tissues. However, hydrogel scaffolds have several limitations, such as weak mechanical property and a lack of bioactive property. On the other hand, noble metal particles, particularly gold (Au) and silver (Ag) nanoparticles (NPs), can be incorporated into the hydrogel matrix to form NP–hydrogel composite scaffolds with enhanced physical and biological properties. This review aims to highlight the potential of these hybrid materials in tissue engineering applications. Additionally, the main approaches that have been used for the synthesis of NP–hydrogel composites and the possible limitations and challenges associated with the application of these materials are discussed
format Article
author Tan, Hui Li
Teow, Sin Yeang *
Pushpamalar, Janarthanan
author_facet Tan, Hui Li
Teow, Sin Yeang *
Pushpamalar, Janarthanan
author_sort Tan, Hui Li
title Application of metal nanoparticle–hydrogel composites in tissue regeneration
title_short Application of metal nanoparticle–hydrogel composites in tissue regeneration
title_full Application of metal nanoparticle–hydrogel composites in tissue regeneration
title_fullStr Application of metal nanoparticle–hydrogel composites in tissue regeneration
title_full_unstemmed Application of metal nanoparticle–hydrogel composites in tissue regeneration
title_sort application of metal nanoparticle–hydrogel composites in tissue regeneration
publisher MDPI
publishDate 2019
url http://eprints.sunway.edu.my/1150/1/Teow%20Sin%20Yeang%20Application%20of%20metal%20NP.pdf
http://eprints.sunway.edu.my/1150/
http://doi.org/10.3390/bioengineering6010017
_version_ 1651870928672391168
score 13.211869

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