Functionalized antimicrobial nanofibers: design criteria and recent advances
The rise of antibiotic resistance has become a major threat to human health and it is spreading globally. It can cause common infectious diseases to be difficult to treat and leads to higher medical costs and increased mortality. Hence, multifunctional polymeric nanofibers with distinctive structure...
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my.iium.irep.933842021-11-25T02:25:36Z http://irep.iium.edu.my/93384/ Functionalized antimicrobial nanofibers: design criteria and recent advances Hamdan, Nazirah Yamin, Alisa Wan Abdul Khodir, Wan Khartini Abd Hamid, Shafida Guarino, Vincenzo QD Chemistry The rise of antibiotic resistance has become a major threat to human health and it is spreading globally. It can cause common infectious diseases to be difficult to treat and leads to higher medical costs and increased mortality. Hence, multifunctional polymeric nanofibers with distinctive structures and unique physiochemical properties have emerged as a neo‐tool to target biofilm and overcome deadly bacterial infections. This review emphasizes electrospun nanofibers’ design criteria and properties that can be utilized to enhance their therapeutic activity for antimi‐ crobial therapy. Also, we present recent progress in designing the surface functionalization of an‐ timicrobial nanofibers with non‐antibiotic agents for effective antibacterial therapy. Lastly, we discuss the future trends and remaining challenges for polymeric nanofibers. MDPI 2021-10-28 Article PeerReviewed application/pdf en http://irep.iium.edu.my/93384/1/93384_Functionalized%20antimicrobial%20nanofibers.pdf application/pdf en http://irep.iium.edu.my/93384/7/93384_Functionalized%20antimicrobial%20nanofibers_Scopus.pdf Hamdan, Nazirah and Yamin, Alisa and Wan Abdul Khodir, Wan Khartini and Abd Hamid, Shafida and Guarino, Vincenzo (2021) Functionalized antimicrobial nanofibers: design criteria and recent advances. Journal of Functional Biomaterials, 12 (4). p. 59. E-ISSN 2079-4983 https://www.mdpi.com/2079-4983/12/4/59 10.3390/jfb12040059 |
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QD Chemistry Hamdan, Nazirah Yamin, Alisa Wan Abdul Khodir, Wan Khartini Abd Hamid, Shafida Guarino, Vincenzo Functionalized antimicrobial nanofibers: design criteria and recent advances |
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The rise of antibiotic resistance has become a major threat to human health and it is spreading globally. It can cause common infectious diseases to be difficult to treat and leads to higher medical costs and increased mortality. Hence, multifunctional polymeric nanofibers with distinctive structures and unique physiochemical properties have emerged as a neo‐tool to target biofilm and overcome deadly bacterial infections. This review emphasizes electrospun nanofibers’ design criteria and properties that can be utilized to enhance their therapeutic activity for antimi‐ crobial therapy. Also, we present recent progress in designing the surface functionalization of an‐ timicrobial nanofibers with non‐antibiotic agents for effective antibacterial therapy. Lastly, we discuss the future trends and remaining challenges for polymeric nanofibers. |
format |
Article |
author |
Hamdan, Nazirah Yamin, Alisa Wan Abdul Khodir, Wan Khartini Abd Hamid, Shafida Guarino, Vincenzo |
author_facet |
Hamdan, Nazirah Yamin, Alisa Wan Abdul Khodir, Wan Khartini Abd Hamid, Shafida Guarino, Vincenzo |
author_sort |
Hamdan, Nazirah |
title |
Functionalized antimicrobial nanofibers: design criteria and recent advances |
title_short |
Functionalized antimicrobial nanofibers: design criteria and recent advances |
title_full |
Functionalized antimicrobial nanofibers: design criteria and recent advances |
title_fullStr |
Functionalized antimicrobial nanofibers: design criteria and recent advances |
title_full_unstemmed |
Functionalized antimicrobial nanofibers: design criteria and recent advances |
title_sort |
functionalized antimicrobial nanofibers: design criteria and recent advances |
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MDPI |
publishDate |
2021 |
url |
http://irep.iium.edu.my/93384/1/93384_Functionalized%20antimicrobial%20nanofibers.pdf http://irep.iium.edu.my/93384/7/93384_Functionalized%20antimicrobial%20nanofibers_Scopus.pdf http://irep.iium.edu.my/93384/ https://www.mdpi.com/2079-4983/12/4/59 |
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1718925602180825088 |
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13.211869 |