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Correlation study between clinical special tests for myelopathy and static MRI parameters in patients of Malaysian population treated for cervical dysfunction

Introduction: Cervical spondylotic myelopathy (CSM) is the most common cause of spinal cord dysfunction. Magnetic resonance imaging (MRI) remains the imaging modality of choice, but its findings are not completely specific for clinically significant CSM. This cross-sectional study aims to determine...

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Main Authors: Zakaria@Mohamad, Zamzuri, Sharifudin, Mohd Ariff, Din, Hishamudin, Abd. Aziz, Azian, Karupiah, Rajandra Kumar
Format: Article
Language:English
Published: Cureus, Inc. 2021
Subjects:
RD701 Orthopedics
Online Access:http://irep.iium.edu.my/93294/7/93294_Correlation%20study%20between%20clinical%20special%20tests%20for%20myelopathy%20and%20static%20MRI%20parameters%20in%20patients%20of%20Malaysian%20population%20treated.pdf
http://irep.iium.edu.my/93294/
https://www.cureus.com/articles/73920-correlation-study-between-clinical-special-tests-for-myelopathy-and-static-mri-parameters-in-patients-of-malaysian-population-treated-for-cervical-dysfunction
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spelling my.iium.irep.932942021-10-25T04:42:34Z http://irep.iium.edu.my/93294/ Correlation study between clinical special tests for myelopathy and static MRI parameters in patients of Malaysian population treated for cervical dysfunction Zakaria@Mohamad, Zamzuri Sharifudin, Mohd Ariff Din, Hishamudin Abd. Aziz, Azian Karupiah, Rajandra Kumar RD701 Orthopedics Introduction: Cervical spondylotic myelopathy (CSM) is the most common cause of spinal cord dysfunction. Magnetic resonance imaging (MRI) remains the imaging modality of choice, but its findings are not completely specific for clinically significant CSM. This cross-sectional study aims to determine the pathoanatomy of CSM in patients and analyze the correlations between clinical key symptoms, myelopathic signs, and MRI findings. Methods: Patients with CSM aged 30 to 80 years old with no previous cervical spine disease or injuries were recruited. Clinical parameters include myelopathic hand signs and other clinical-specific tests. The MRI findings were analyzed for level of compression, underlying degenerative pathology, and parameters for cord compression. Results: Thirty patients were recruited. The most common myelopathic signs observed were positive Hoffmann’s sign and the presence of reverse brachioradialis reflex. All patients had either degenerative or prolapse disc changes on MRI. There was a positive correlation between the clinical key features with MRI parameters for canal and cord diameter. The transverse cord diameter, cord compression ratio, and approximate cord area were the only independent variables related to almost all the positive clinical specific tests. All three have a moderate to strong correlation with the clinical findings. Conclusion: The MRI parameters such as canal and cord size of the cervical spine are an objective reflection of compression on the spinal cord. Correlations observed indicate cord compression that plays a major role in the pathophysiology of CSM. These measurements are sensitive indicators of canal stenosis and play a significant role in predicting the severity and outcome of CSM. Cureus, Inc. 2021-10-16 Article PeerReviewed application/pdf en http://irep.iium.edu.my/93294/7/93294_Correlation%20study%20between%20clinical%20special%20tests%20for%20myelopathy%20and%20static%20MRI%20parameters%20in%20patients%20of%20Malaysian%20population%20treated.pdf Zakaria@Mohamad, Zamzuri and Sharifudin, Mohd Ariff and Din, Hishamudin and Abd. Aziz, Azian and Karupiah, Rajandra Kumar (2021) Correlation study between clinical special tests for myelopathy and static MRI parameters in patients of Malaysian population treated for cervical dysfunction. Cureus, 13 (10). pp. 1-14. ISSN 2168-8184 https://www.cureus.com/articles/73920-correlation-study-between-clinical-special-tests-for-myelopathy-and-static-mri-parameters-in-patients-of-malaysian-population-treated-for-cervical-dysfunction 10.7759/cureus.18826
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic RD701 Orthopedics
spellingShingle RD701 Orthopedics
Zakaria@Mohamad, Zamzuri
Sharifudin, Mohd Ariff
Din, Hishamudin
Abd. Aziz, Azian
Karupiah, Rajandra Kumar
Correlation study between clinical special tests for myelopathy and static MRI parameters in patients of Malaysian population treated for cervical dysfunction
description Introduction: Cervical spondylotic myelopathy (CSM) is the most common cause of spinal cord dysfunction. Magnetic resonance imaging (MRI) remains the imaging modality of choice, but its findings are not completely specific for clinically significant CSM. This cross-sectional study aims to determine the pathoanatomy of CSM in patients and analyze the correlations between clinical key symptoms, myelopathic signs, and MRI findings. Methods: Patients with CSM aged 30 to 80 years old with no previous cervical spine disease or injuries were recruited. Clinical parameters include myelopathic hand signs and other clinical-specific tests. The MRI findings were analyzed for level of compression, underlying degenerative pathology, and parameters for cord compression. Results: Thirty patients were recruited. The most common myelopathic signs observed were positive Hoffmann’s sign and the presence of reverse brachioradialis reflex. All patients had either degenerative or prolapse disc changes on MRI. There was a positive correlation between the clinical key features with MRI parameters for canal and cord diameter. The transverse cord diameter, cord compression ratio, and approximate cord area were the only independent variables related to almost all the positive clinical specific tests. All three have a moderate to strong correlation with the clinical findings. Conclusion: The MRI parameters such as canal and cord size of the cervical spine are an objective reflection of compression on the spinal cord. Correlations observed indicate cord compression that plays a major role in the pathophysiology of CSM. These measurements are sensitive indicators of canal stenosis and play a significant role in predicting the severity and outcome of CSM.
format Article
author Zakaria@Mohamad, Zamzuri
Sharifudin, Mohd Ariff
Din, Hishamudin
Abd. Aziz, Azian
Karupiah, Rajandra Kumar
author_facet Zakaria@Mohamad, Zamzuri
Sharifudin, Mohd Ariff
Din, Hishamudin
Abd. Aziz, Azian
Karupiah, Rajandra Kumar
author_sort Zakaria@Mohamad, Zamzuri
title Correlation study between clinical special tests for myelopathy and static MRI parameters in patients of Malaysian population treated for cervical dysfunction
title_short Correlation study between clinical special tests for myelopathy and static MRI parameters in patients of Malaysian population treated for cervical dysfunction
title_full Correlation study between clinical special tests for myelopathy and static MRI parameters in patients of Malaysian population treated for cervical dysfunction
title_fullStr Correlation study between clinical special tests for myelopathy and static MRI parameters in patients of Malaysian population treated for cervical dysfunction
title_full_unstemmed Correlation study between clinical special tests for myelopathy and static MRI parameters in patients of Malaysian population treated for cervical dysfunction
title_sort correlation study between clinical special tests for myelopathy and static mri parameters in patients of malaysian population treated for cervical dysfunction
publisher Cureus, Inc.
publishDate 2021
url http://irep.iium.edu.my/93294/7/93294_Correlation%20study%20between%20clinical%20special%20tests%20for%20myelopathy%20and%20static%20MRI%20parameters%20in%20patients%20of%20Malaysian%20population%20treated.pdf
http://irep.iium.edu.my/93294/
https://www.cureus.com/articles/73920-correlation-study-between-clinical-special-tests-for-myelopathy-and-static-mri-parameters-in-patients-of-malaysian-population-treated-for-cervical-dysfunction
_version_ 1715189418416930816
score 13.211869

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