Discovery of new inhibitor for the Protein Arginine Deiminase Type 4 (PAD4) by Rational Design of α-Enolase-derived Peptides
Rheumatoid arthritis (RA) is an inflammatory autoimmune disease affecting about 0.5–1.0% of the world population. Protein arginine deiminase type 4 (PAD4) is believed to be responsible for the occurrence of RA by catalyzing citrullination of proteins. The citrullinated proteins act as autoantigens b...
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Main Authors: | Ahmad Nadzirin, Izzuddin, Chor, Adam Leow Thean, Salleh, Abu Bakar, Abdul Rahman, Mohd Basyaruddin, Tejo, Bimo Ario |
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Format: | Article |
Language: | English English |
Published: |
Elsevier Ltd.
2021
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Subjects: | |
Online Access: | http://irep.iium.edu.my/92776/7/92776_Discovery%20of%20new%20inhibitor%20for%20the%20Protein%20Arginine%20Deiminase%20Type%204%20%28PAD4%29.pdf http://irep.iium.edu.my/92776/8/92776_Discovery%20of%20new%20inhibitor%20for%20the%20Protein%20Arginine%20Deiminase%20Type%204%20%28PAD4%29_Scopus.pdf http://irep.iium.edu.my/92776/ https://www.sciencedirect.com/science/article/abs/pii/S1476927121000542 |
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