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B Cell Lymphoma of Thoracic Vertebrae: a great mimicker

Non-Hodgkin lymphoma (NHL) is a malignant neoplasm affecting multiple systems in which extranodal NHL represents 10-20% of all NHL. This is a case of a 45-year-old female with no known medical illness who presented with progressive numbness of bilateral lower limbs since March 2016 which subseque...

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Main Authors: W Mustapha, Wan Irfan, Md Ralib @ Md Raghib, Ahmad Razali
Format: Article
Language:English
Published: IIUM Press 2019
Subjects:
R Medicine (General)
Online Access:http://irep.iium.edu.my/92741/1/92741_B%20Cell%20Lymphoma%20of%20Thoracic%20Vertebrae.pdf
http://irep.iium.edu.my/92741/
https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/406/229
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spelling my.iium.irep.927412021-10-07T03:10:20Z http://irep.iium.edu.my/92741/ B Cell Lymphoma of Thoracic Vertebrae: a great mimicker W Mustapha, Wan Irfan Md Ralib @ Md Raghib, Ahmad Razali R Medicine (General) Non-Hodgkin lymphoma (NHL) is a malignant neoplasm affecting multiple systems in which extranodal NHL represents 10-20% of all NHL. This is a case of a 45-year-old female with no known medical illness who presented with progressive numbness of bilateral lower limbs since March 2016 which subsequently progress to loss of motor power since November 2016. She initially was diagnosed as tuberculous (TB) spondylitis which then turned out to be B cell lymphoma of the thoracic vertebra. The diagnosis was confirmed on histopathological examination (HPE) after the patient underwent laminectomy of T3-T7 vertebra bodies and excision biopsy with the removal of the caseous material. Due to a lack of specific findings, the diagnosis of vertebral NHL is often missed or delayed. It warrants the attention that NHL of a thoracic vertebra may be misdiagnosed as TB spondylitis due to their similarities, and sometimes the imaging features may simulate and overlap each other. The main treatment for vertebral NHL is chemotherapy, radiotherapy or both. Surgery may be necessary if the patient has a story of neurological deficits. However, the patient was treated conservatively as she refused chemotherapy. IIUM Press 2019-12-29 Article PeerReviewed application/pdf en http://irep.iium.edu.my/92741/1/92741_B%20Cell%20Lymphoma%20of%20Thoracic%20Vertebrae.pdf W Mustapha, Wan Irfan and Md Ralib @ Md Raghib, Ahmad Razali (2019) B Cell Lymphoma of Thoracic Vertebrae: a great mimicker. International Journal of Allied Health Sciences (IJAHS), 3 (3 Special Issue). E-ISSN 2600-8491 https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/406/229
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic R Medicine (General)
spellingShingle R Medicine (General)
W Mustapha, Wan Irfan
Md Ralib @ Md Raghib, Ahmad Razali
B Cell Lymphoma of Thoracic Vertebrae: a great mimicker
description Non-Hodgkin lymphoma (NHL) is a malignant neoplasm affecting multiple systems in which extranodal NHL represents 10-20% of all NHL. This is a case of a 45-year-old female with no known medical illness who presented with progressive numbness of bilateral lower limbs since March 2016 which subsequently progress to loss of motor power since November 2016. She initially was diagnosed as tuberculous (TB) spondylitis which then turned out to be B cell lymphoma of the thoracic vertebra. The diagnosis was confirmed on histopathological examination (HPE) after the patient underwent laminectomy of T3-T7 vertebra bodies and excision biopsy with the removal of the caseous material. Due to a lack of specific findings, the diagnosis of vertebral NHL is often missed or delayed. It warrants the attention that NHL of a thoracic vertebra may be misdiagnosed as TB spondylitis due to their similarities, and sometimes the imaging features may simulate and overlap each other. The main treatment for vertebral NHL is chemotherapy, radiotherapy or both. Surgery may be necessary if the patient has a story of neurological deficits. However, the patient was treated conservatively as she refused chemotherapy.
format Article
author W Mustapha, Wan Irfan
Md Ralib @ Md Raghib, Ahmad Razali
author_facet W Mustapha, Wan Irfan
Md Ralib @ Md Raghib, Ahmad Razali
author_sort W Mustapha, Wan Irfan
title B Cell Lymphoma of Thoracic Vertebrae: a great mimicker
title_short B Cell Lymphoma of Thoracic Vertebrae: a great mimicker
title_full B Cell Lymphoma of Thoracic Vertebrae: a great mimicker
title_fullStr B Cell Lymphoma of Thoracic Vertebrae: a great mimicker
title_full_unstemmed B Cell Lymphoma of Thoracic Vertebrae: a great mimicker
title_sort b cell lymphoma of thoracic vertebrae: a great mimicker
publisher IIUM Press
publishDate 2019
url http://irep.iium.edu.my/92741/1/92741_B%20Cell%20Lymphoma%20of%20Thoracic%20Vertebrae.pdf
http://irep.iium.edu.my/92741/
https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/406/229
_version_ 1713199561250439168
score 13.211869

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