PIP4Ks impact on PI3K, FOXP3, and UHRF1 signaling and modulate human regulatory T cell proliferation and immunosuppressive activity
Regulatory T cells (Tregs) play fundamental roles in maintaining peripheral tolerance to prevent autoimmunity and limit legitimate immune responses, a feature hijacked in tumor microenvironments in which the recruitment of Tregs often extinguishes immune surveillance through suppression of T-effecto...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
National Academy of Sciences
2021
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/92431/1/92431_PIP4Ks%20impact%20on%20PI3K%2C%20FOXP3%2C%20and%20UHRF1%20signaling.pdf http://irep.iium.edu.my/92431/2/92431_PIP4Ks%20impact%20on%20PI3K%2C%20FOXP3%2C%20and%20UHRF1%20signaling_SCOPUS.pdf http://irep.iium.edu.my/92431/ https://www.pnas.org/content/118/31/e2010053118.short https://doi.org/10.1073/pnas.2010053118 |
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