Alzheimer's disease: from bench side to bed side
Drug systematic administration to brain is challenged by blood–brain barrier (BBB). Only small lipophilic drugs cross BBB. Nearly 100% of biologics cannot cross BBB. Biologics composed 33% of FDA-approved drugs in 2019. Nanoparticles were used to cross BBB after suitable surface modification with mo...
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my.iium.irep.882402021-02-05T01:42:48Z http://irep.iium.edu.my/88240/ Alzheimer's disease: from bench side to bed side Mohamed, Wael Mohamed Yousef Yoon, Chee Kok Doolaanea, Abd Almonem RM Therapeutics. Pharmacology RS Pharmacy and materia medica Drug systematic administration to brain is challenged by blood–brain barrier (BBB). Only small lipophilic drugs cross BBB. Nearly 100% of biologics cannot cross BBB. Biologics composed 33% of FDA-approved drugs in 2019. Nanoparticles were used to cross BBB after suitable surface modification with molecules to recognize receptors on BBB. 2020-12-01 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/88240/2/BNC%202020%20Hi5%202020%20Dr%20Abd%20Almonem.pdf application/pdf en http://irep.iium.edu.my/88240/14/Hi5%202020_Tentative_Final_29%20NOV%202020.pdf application/pdf en http://irep.iium.edu.my/88240/15/E%20PROGRAM%20BOOK%20BNC%20Hi5%20Retreat%202020.pdf application/pdf en http://irep.iium.edu.my/88240/17/Translational%20Forum%20Invitation%20Letter_%20Dr%20Wael%20et%20al.pdf application/pdf en http://irep.iium.edu.my/88240/16/01%20Cert_Hi5_Attendance.pdf Mohamed, Wael Mohamed Yousef and Yoon, Chee Kok and Doolaanea, Abd Almonem (2020) Alzheimer's disease: from bench side to bed side. In: Hi-5 Retreat 2020: V-Symposium Basic Neuroscience Council (BNC), 1st - 4th December 2020, Kuala Lumpur, Malaysia. (Unpublished) |
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RM Therapeutics. Pharmacology RS Pharmacy and materia medica Mohamed, Wael Mohamed Yousef Yoon, Chee Kok Doolaanea, Abd Almonem Alzheimer's disease: from bench side to bed side |
description |
Drug systematic administration to brain is challenged by blood–brain barrier (BBB). Only small lipophilic drugs cross BBB. Nearly 100% of biologics cannot cross BBB. Biologics composed 33% of FDA-approved drugs in 2019. Nanoparticles were used to cross BBB after suitable surface modification with molecules to recognize receptors on BBB. |
format |
Conference or Workshop Item |
author |
Mohamed, Wael Mohamed Yousef Yoon, Chee Kok Doolaanea, Abd Almonem |
author_facet |
Mohamed, Wael Mohamed Yousef Yoon, Chee Kok Doolaanea, Abd Almonem |
author_sort |
Mohamed, Wael Mohamed Yousef |
title |
Alzheimer's disease: from bench side to bed side |
title_short |
Alzheimer's disease: from bench side to bed side |
title_full |
Alzheimer's disease: from bench side to bed side |
title_fullStr |
Alzheimer's disease: from bench side to bed side |
title_full_unstemmed |
Alzheimer's disease: from bench side to bed side |
title_sort |
alzheimer's disease: from bench side to bed side |
publishDate |
2020 |
url |
http://irep.iium.edu.my/88240/2/BNC%202020%20Hi5%202020%20Dr%20Abd%20Almonem.pdf http://irep.iium.edu.my/88240/14/Hi5%202020_Tentative_Final_29%20NOV%202020.pdf http://irep.iium.edu.my/88240/15/E%20PROGRAM%20BOOK%20BNC%20Hi5%20Retreat%202020.pdf http://irep.iium.edu.my/88240/17/Translational%20Forum%20Invitation%20Letter_%20Dr%20Wael%20et%20al.pdf http://irep.iium.edu.my/88240/16/01%20Cert_Hi5_Attendance.pdf http://irep.iium.edu.my/88240/ |
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1691732930346352640 |
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13.211869 |