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Phytochemistry, traditional use and pharmacological activity of picrasma quassioides: a critical reviews

Picrasma quassioides is a member of the Simaroubaceae family commonly grown in the regions of Asia, the Himalayas, and India and has been used as a traditional herbal medicine to treat various illnesses such as fever, gastric discomfort, and pediculosis. This study aims to critically review the pre...

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Main Authors: Mohd Jamil, Muhammad Daniel Hakim, Bakhtiar, M. Taher, Darnis, Deny Susanti, Rahman, Md Atiar, Zakaria, Zainul Amiruddin
Format: Article
Language:English
English
Published: MDPI 2020
Subjects:
RS192 Materia Medica-Pharmaceutical Technology
Online Access:http://irep.iium.edu.my/82482/7/82482_Phytochemistry%2C%20traditional%20use%20and%20pharmacological%20activity%20of%20picrasma%20quassioides%20a%20critical%20reviews.pdf
http://irep.iium.edu.my/82482/13/82482_Phytochemistry%2C%20traditional%20use.pdf
http://irep.iium.edu.my/82482/
https://www.mdpi.com/journal/nutrients%20
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spelling my.iium.irep.824822021-02-10T03:27:53Z http://irep.iium.edu.my/82482/ Phytochemistry, traditional use and pharmacological activity of picrasma quassioides: a critical reviews Mohd Jamil, Muhammad Daniel Hakim Bakhtiar, M. Taher Darnis, Deny Susanti Rahman, Md Atiar Zakaria, Zainul Amiruddin RS192 Materia Medica-Pharmaceutical Technology Picrasma quassioides is a member of the Simaroubaceae family commonly grown in the regions of Asia, the Himalayas, and India and has been used as a traditional herbal medicine to treat various illnesses such as fever, gastric discomfort, and pediculosis. This study aims to critically review the presence of phytochemicals in P. quassioides and correlate their pharmacological activities with the significance of its use as traditional medicine. Data were collected by reviewing numerous scientific articles from several journal databases on the pharmacological activities of P. quassioides using certain keywords. As a result, approximately 94 phytochemicals extracted from P. quassioides were found to be associated with quassinoids, β-carbolines and canthinones. These molecules exhibited various pharmacological benefits such as anti-inflammatory, antioxidant, anti-cancer, anti-microbial, and anti-parasitic activities which help to treat different diseases. However, P. quassioides were also found to have several toxicity effects in high doses, although the evidence regarding these effects is limited in proving its safe use and efficacy as herbal medicine. Accordingly, while it can be concluded that P. quassioides may have many potential pharmacological benefits with more phytochemistry discoveries, further research is required to determine its real value in terms of quality, safety, and efficacy of use. MDPI 2020-09 Article PeerReviewed application/pdf en http://irep.iium.edu.my/82482/7/82482_Phytochemistry%2C%20traditional%20use%20and%20pharmacological%20activity%20of%20picrasma%20quassioides%20a%20critical%20reviews.pdf application/pdf en http://irep.iium.edu.my/82482/13/82482_Phytochemistry%2C%20traditional%20use.pdf Mohd Jamil, Muhammad Daniel Hakim and Bakhtiar, M. Taher and Darnis, Deny Susanti and Rahman, Md Atiar and Zakaria, Zainul Amiruddin (2020) Phytochemistry, traditional use and pharmacological activity of picrasma quassioides: a critical reviews. Nutrients, 12 (2584). pp. 1-16. ISSN 2072-6643 https://www.mdpi.com/journal/nutrients%20
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
English
topic RS192 Materia Medica-Pharmaceutical Technology
spellingShingle RS192 Materia Medica-Pharmaceutical Technology
Mohd Jamil, Muhammad Daniel Hakim
Bakhtiar, M. Taher
Darnis, Deny Susanti
Rahman, Md Atiar
Zakaria, Zainul Amiruddin
Phytochemistry, traditional use and pharmacological activity of picrasma quassioides: a critical reviews
description Picrasma quassioides is a member of the Simaroubaceae family commonly grown in the regions of Asia, the Himalayas, and India and has been used as a traditional herbal medicine to treat various illnesses such as fever, gastric discomfort, and pediculosis. This study aims to critically review the presence of phytochemicals in P. quassioides and correlate their pharmacological activities with the significance of its use as traditional medicine. Data were collected by reviewing numerous scientific articles from several journal databases on the pharmacological activities of P. quassioides using certain keywords. As a result, approximately 94 phytochemicals extracted from P. quassioides were found to be associated with quassinoids, β-carbolines and canthinones. These molecules exhibited various pharmacological benefits such as anti-inflammatory, antioxidant, anti-cancer, anti-microbial, and anti-parasitic activities which help to treat different diseases. However, P. quassioides were also found to have several toxicity effects in high doses, although the evidence regarding these effects is limited in proving its safe use and efficacy as herbal medicine. Accordingly, while it can be concluded that P. quassioides may have many potential pharmacological benefits with more phytochemistry discoveries, further research is required to determine its real value in terms of quality, safety, and efficacy of use.
format Article
author Mohd Jamil, Muhammad Daniel Hakim
Bakhtiar, M. Taher
Darnis, Deny Susanti
Rahman, Md Atiar
Zakaria, Zainul Amiruddin
author_facet Mohd Jamil, Muhammad Daniel Hakim
Bakhtiar, M. Taher
Darnis, Deny Susanti
Rahman, Md Atiar
Zakaria, Zainul Amiruddin
author_sort Mohd Jamil, Muhammad Daniel Hakim
title Phytochemistry, traditional use and pharmacological activity of picrasma quassioides: a critical reviews
title_short Phytochemistry, traditional use and pharmacological activity of picrasma quassioides: a critical reviews
title_full Phytochemistry, traditional use and pharmacological activity of picrasma quassioides: a critical reviews
title_fullStr Phytochemistry, traditional use and pharmacological activity of picrasma quassioides: a critical reviews
title_full_unstemmed Phytochemistry, traditional use and pharmacological activity of picrasma quassioides: a critical reviews
title_sort phytochemistry, traditional use and pharmacological activity of picrasma quassioides: a critical reviews
publisher MDPI
publishDate 2020
url http://irep.iium.edu.my/82482/7/82482_Phytochemistry%2C%20traditional%20use%20and%20pharmacological%20activity%20of%20picrasma%20quassioides%20a%20critical%20reviews.pdf
http://irep.iium.edu.my/82482/13/82482_Phytochemistry%2C%20traditional%20use.pdf
http://irep.iium.edu.my/82482/
https://www.mdpi.com/journal/nutrients%20
_version_ 1691732907248320512
score 13.211869

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