Phytochemicals with antifungal properties: Cure from nature

Aims: The exploration of natural products with innovative uses is dynamic and expanding rapidly. Medicinal plants have fascinated many researchers that subsequently lead to research publications highlighting plant extracts with wide range of secondary metabolites such as flavonoids, alkaloids, gly...

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Main Authors: Elgharbawy, Amal A.M., Samsudin, Nurhusna, Benbelgacem, Farah Fadwa, Hashim, Yumi Zuhanis Has-Yun, Salleh, Hamzah Mohd., Santhanam, Jacinta
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Language:English
English
English
English
Published: 2020
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spelling my.iium.irep.819952020-12-29T08:23:03Z http://irep.iium.edu.my/81995/ Phytochemicals with antifungal properties: Cure from nature Elgharbawy, Amal A.M. Samsudin, Nurhusna Benbelgacem, Farah Fadwa Hashim, Yumi Zuhanis Has-Yun Salleh, Hamzah Mohd. Santhanam, Jacinta TP248.13 Biotechnology TX341 Nutrition. Foods and food supply Aims: The exploration of natural products with innovative uses is dynamic and expanding rapidly. Medicinal plants have fascinated many researchers that subsequently lead to research publications highlighting plant extracts with wide range of secondary metabolites such as flavonoids, alkaloids, glycosides, quinones, terpenoids, tannins and saponins that exhibit antimicrobial activities and disease control. The concentration of these bioactive compounds in each plant species varies based on the pathosystem and environmental conditions. This study aims to uncover the various types of phytochemicals with antifungal properties. Methodology and results: Seven categories of plant-based antifungal compounds were reviewed, which are terpenoids, saponins, phenolic compounds, coumarins, alkaloids, essential oils and peptides, with examples and structures of some available compounds. The mechanism of action of each category of phytochemical was discussed. Also, the impact of some compounds was explained and elaborated. Conclusion, significance and impact of study: It is of a great importance to explore natural plant fighters against fungal infection. Those active plant components do not only have antifungal properties, but they also help in the healing process and some even exhibit anticancer activities. The development and knowledge of antifungal activities from plant extracts have the potential for applications in antifungal therapy. Since the exact description of how antifungal compounds function in the human body is still unclear more studies are required to unveil phytochemicals’ properties and to elucidate their effects on living cells. 2020-08 Article PeerReviewed application/pdf en http://irep.iium.edu.my/81995/1/elgharbawy%20et%20al.%202020_mjm.pdf application/pdf en http://irep.iium.edu.my/81995/3/Malaysian%20Journal%20of%20Microbiology_MyJurnal%20-%20Malaysia%20Citation%20Centre.pdf application/pdf en http://irep.iium.edu.my/81995/5/Malaysian%20Journal%20of%20Microbiology_Web%20of%20Science%20Master%20Journal%20List%20-%20Journal%20Profile.pdf application/pdf en http://irep.iium.edu.my/81995/32/81995_Phytochemicals%20with%20antifungal%20properties_SCOPUS.pdf Elgharbawy, Amal A.M. and Samsudin, Nurhusna and Benbelgacem, Farah Fadwa and Hashim, Yumi Zuhanis Has-Yun and Salleh, Hamzah Mohd. and Santhanam, Jacinta (2020) Phytochemicals with antifungal properties: Cure from nature. Malaysian Journal of Microbiology, 16 (4). pp. 323-345. ISSN 1823-8262 E-ISSN 2231-7538
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
English
English
English
topic TP248.13 Biotechnology
TX341 Nutrition. Foods and food supply
spellingShingle TP248.13 Biotechnology
TX341 Nutrition. Foods and food supply
Elgharbawy, Amal A.M.
Samsudin, Nurhusna
Benbelgacem, Farah Fadwa
Hashim, Yumi Zuhanis Has-Yun
Salleh, Hamzah Mohd.
Santhanam, Jacinta
Phytochemicals with antifungal properties: Cure from nature
description Aims: The exploration of natural products with innovative uses is dynamic and expanding rapidly. Medicinal plants have fascinated many researchers that subsequently lead to research publications highlighting plant extracts with wide range of secondary metabolites such as flavonoids, alkaloids, glycosides, quinones, terpenoids, tannins and saponins that exhibit antimicrobial activities and disease control. The concentration of these bioactive compounds in each plant species varies based on the pathosystem and environmental conditions. This study aims to uncover the various types of phytochemicals with antifungal properties. Methodology and results: Seven categories of plant-based antifungal compounds were reviewed, which are terpenoids, saponins, phenolic compounds, coumarins, alkaloids, essential oils and peptides, with examples and structures of some available compounds. The mechanism of action of each category of phytochemical was discussed. Also, the impact of some compounds was explained and elaborated. Conclusion, significance and impact of study: It is of a great importance to explore natural plant fighters against fungal infection. Those active plant components do not only have antifungal properties, but they also help in the healing process and some even exhibit anticancer activities. The development and knowledge of antifungal activities from plant extracts have the potential for applications in antifungal therapy. Since the exact description of how antifungal compounds function in the human body is still unclear more studies are required to unveil phytochemicals’ properties and to elucidate their effects on living cells.
format Article
author Elgharbawy, Amal A.M.
Samsudin, Nurhusna
Benbelgacem, Farah Fadwa
Hashim, Yumi Zuhanis Has-Yun
Salleh, Hamzah Mohd.
Santhanam, Jacinta
author_facet Elgharbawy, Amal A.M.
Samsudin, Nurhusna
Benbelgacem, Farah Fadwa
Hashim, Yumi Zuhanis Has-Yun
Salleh, Hamzah Mohd.
Santhanam, Jacinta
author_sort Elgharbawy, Amal A.M.
title Phytochemicals with antifungal properties: Cure from nature
title_short Phytochemicals with antifungal properties: Cure from nature
title_full Phytochemicals with antifungal properties: Cure from nature
title_fullStr Phytochemicals with antifungal properties: Cure from nature
title_full_unstemmed Phytochemicals with antifungal properties: Cure from nature
title_sort phytochemicals with antifungal properties: cure from nature
publishDate 2020
url http://irep.iium.edu.my/81995/1/elgharbawy%20et%20al.%202020_mjm.pdf
http://irep.iium.edu.my/81995/3/Malaysian%20Journal%20of%20Microbiology_MyJurnal%20-%20Malaysia%20Citation%20Centre.pdf
http://irep.iium.edu.my/81995/5/Malaysian%20Journal%20of%20Microbiology_Web%20of%20Science%20Master%20Journal%20List%20-%20Journal%20Profile.pdf
http://irep.iium.edu.my/81995/32/81995_Phytochemicals%20with%20antifungal%20properties_SCOPUS.pdf
http://irep.iium.edu.my/81995/
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