Selectivity filter instability dominates the low intrinsic activity of the TWIK-1 K2P K+ channel
Two-pore domain K+ (K2P) channels have many important physiological functions. However, the functional properties of the TWIK-1 (K2P1.1/KCNK1) K2P channel remain poorly characterized because heterologous expression of this ion channel yields only very low levels of functional activity. Several under...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English English English English |
| Published: |
American Society for Biochemistry and Molecular Biology Publications
2020
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/79624/1/79624_Selectivity%20filter%20instability%20dominates%20-%20pre-print.pdf http://irep.iium.edu.my/79624/2/79624_Selectivity%20filter%20instability%20dominates_MYRA.pdf http://irep.iium.edu.my/79624/3/79624_Selectivity%20filter%20instability%20dominates_SCOPUS.pdf http://irep.iium.edu.my/79624/4/79624_Selectivity%20filter%20instability%20dominates_WOS.pdf http://irep.iium.edu.my/79624/ https://www.jbc.org/content/295/2/610.short |
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