Staff View: Bactericidal efficacy of selected medicinal plant crude extracts and their fractions against common fish pathogens = Keberkesanan bakterisid ialah ekstrak mentah tumbuhan ubatan terpilih dan fraksinya terhadap patogen biasa ikan

Bactericidal efficacy of selected medicinal plant crude extracts and their fractions against common fish pathogens = Keberkesanan bakterisid ialah ekstrak mentah tumbuhan ubatan terpilih dan fraksinya terhadap patogen biasa ikan

The emergence of new diseases and the increased use of antibiotics have led to the development of resistant bacterial strains. Thus, there is greater attention to seek new antibacterial agents from the natural sources for combating fish diseases in the aquaculture industry. The present study evalu...

Full description

Saved in:

Bibliographic Details
Main Authors:	Abdul Razak, Rashidah, Shariff, Mohamed, Md. Yusoff, Fatimah, Ismail, Intan Safinar
Format:	Article
Language:	English English English
Published:	Penerbit Universiti Kebangsaan Malaysia 2019
Subjects:	S Agriculture (General) SH Aquaculture. Fisheries. Angling
Online Access:	http://irep.iium.edu.my/79206/1/79206_Bactericidal%20efficacy%20of%20selected%20medicinal.pdf http://irep.iium.edu.my/79206/2/79206_Bactericidal%20efficacy%20of%20selected%20medicinal_SCOPUS.pdf http://irep.iium.edu.my/79206/13/79206_Bactericidal%20Efficacy%20of%20Selected%20Medicinal_WOS.pdf http://irep.iium.edu.my/79206/ http://www.ukm.my/jsm/pdf_files/SM-PDF-48-8-2019/05%20Rashidah%20Abdul%20Razak.pdf
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my.iium.irep.79206
record_format	dspace
institution	Universiti Islam Antarabangsa Malaysia
building	IIUM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	International Islamic University Malaysia
content_source	IIUM Repository (IREP)
url_provider	http://irep.iium.edu.my/
language	English English English
topic	S Agriculture (General) SH Aquaculture. Fisheries. Angling
spellingShingle	S Agriculture (General) SH Aquaculture. Fisheries. Angling Abdul Razak, Rashidah Shariff, Mohamed Md. Yusoff, Fatimah Ismail, Intan Safinar Bactericidal efficacy of selected medicinal plant crude extracts and their fractions against common fish pathogens = Keberkesanan bakterisid ialah ekstrak mentah tumbuhan ubatan terpilih dan fraksinya terhadap patogen biasa ikan
description	The emergence of new diseases and the increased use of antibiotics have led to the development of resistant bacterial strains. Thus, there is greater attention to seek new antibacterial agents from the natural sources for combating fish diseases in the aquaculture industry. The present study evaluated the bactericidal efficacy of crude methanolic and aqueous extracts from Polygonum chinense, Syzygium polyanthum, Premna foetida, Pimenta dioica, Brucea javanica, Vitex negundo, Alpinia conchigera and Clinacanthus nutans against Vibrio harveyi, Vibrio alginolyticus, Vibrio parahaemolyticus and Aeromonas hydrophila using disc diffusion method. The results showed that methanolic extracts of P. dioica, P. foetida and P. chinense, and aqueous extracts of P. dioica and S. polyanthum showed moderate to strong activity (10.8 to 17.2 mm) against all the tested bacteria. These five potential crude extracts were fractionated using liquid-liquid extraction method to obtain the methanol, dichloromethane and ethyl acetate fractions. Among the fractions, ethyl acetate fraction showed the highest activity against all tested bacteria, with minimum inhibition concentration (MIC) values between 0.625 and 10.000 mg/mL. In addition, the five potential crude extracts had low to moderate toxicity with LC50 >100 µg/ mL using brine shrimp cytotoxicity assays. The results of this study indicated that methanolic extracts of P. chinense and P. foetida that showed high bactericidal activity and low toxicity could be good potentials for use in fish culture. ****************************************************************************************** Kemunculan penyakit baharu dan peningkatan penggunaan antibiotik telah membawa kepada penghasilan strain bakteria yang rintang. Oleh itu, terdapat banyak perhatian untuk mencari agen antibakteria baru daripada sumber semula jadi bagi memerangi penyakit ikan dalam industri akuakultur. Kajian ini telah menguji keberkesanan bakterisid bagi ekstrak mentah metanolik dan akueus daripada Polygonum chinense, Syzygium polyanthum, Premna foetida, Pimenta dioica, Brucea javanica, Vitex negundo, Alphinia conchigera dan Clinacanthus nutans terhadap Vibrio harveyi, Vibrio alginolyticus, Vibrio parahaemolyticus dan Aeromonas hydrophila menggunakan kaedah penyebaran cakera. Hasil kajian telah menunjukkan ekstrak metanolik P. dioica, P. foetida dan P. chinense, dan ekstrak akueus P. dioica serta S. polyanthum mempunyai aktiviti antimikrob sederhana hingga kuat (10.8 hingga 17.2 mm) terhadap semua bakteria yang diuji. Kesemua lima ekstrak mentah yang berpotensi ini seterusnya difraksikan menggunakan kaedah pengekstrakan cecair-cecair untuk mendapatkan fraksi metanol, diklorometana dan etil asetat. Antara fraksi ini, fraksi etil asetat menunjukkan aktiviti tertinggi terhadap semua bakteria yang diuji dengan nilai kepekatan perencatan minimum (MIC) antara 0.625 hingga 10.000 mg/mL. Di samping itu, lima ekstrak mentah yang berpotensi ini mempunyai ketoksikan yang rendah hingga sederhana dengan LC50> 100 μg/mL menggunakan pengasaian kesitotoksikan udang brin. Hasil kajian ini menunjukkan bahawa ekstrak metanolik P. chinense dan P. foetida yang mempunyai aktiviti bakterisid tinggi dan ketoksikan rendah mempunyai potensi yang baik untuk digunakan dalam kultur ikan.
format	Article
author	Abdul Razak, Rashidah Shariff, Mohamed Md. Yusoff, Fatimah Ismail, Intan Safinar
author_facet	Abdul Razak, Rashidah Shariff, Mohamed Md. Yusoff, Fatimah Ismail, Intan Safinar
author_sort	Abdul Razak, Rashidah
title	Bactericidal efficacy of selected medicinal plant crude extracts and their fractions against common fish pathogens = Keberkesanan bakterisid ialah ekstrak mentah tumbuhan ubatan terpilih dan fraksinya terhadap patogen biasa ikan
title_short	Bactericidal efficacy of selected medicinal plant crude extracts and their fractions against common fish pathogens = Keberkesanan bakterisid ialah ekstrak mentah tumbuhan ubatan terpilih dan fraksinya terhadap patogen biasa ikan
title_full	Bactericidal efficacy of selected medicinal plant crude extracts and their fractions against common fish pathogens = Keberkesanan bakterisid ialah ekstrak mentah tumbuhan ubatan terpilih dan fraksinya terhadap patogen biasa ikan
title_fullStr	Bactericidal efficacy of selected medicinal plant crude extracts and their fractions against common fish pathogens = Keberkesanan bakterisid ialah ekstrak mentah tumbuhan ubatan terpilih dan fraksinya terhadap patogen biasa ikan
title_full_unstemmed	Bactericidal efficacy of selected medicinal plant crude extracts and their fractions against common fish pathogens = Keberkesanan bakterisid ialah ekstrak mentah tumbuhan ubatan terpilih dan fraksinya terhadap patogen biasa ikan
title_sort	bactericidal efficacy of selected medicinal plant crude extracts and their fractions against common fish pathogens = keberkesanan bakterisid ialah ekstrak mentah tumbuhan ubatan terpilih dan fraksinya terhadap patogen biasa ikan
publisher	Penerbit Universiti Kebangsaan Malaysia
publishDate	2019
url	http://irep.iium.edu.my/79206/1/79206_Bactericidal%20efficacy%20of%20selected%20medicinal.pdf http://irep.iium.edu.my/79206/2/79206_Bactericidal%20efficacy%20of%20selected%20medicinal_SCOPUS.pdf http://irep.iium.edu.my/79206/13/79206_Bactericidal%20Efficacy%20of%20Selected%20Medicinal_WOS.pdf http://irep.iium.edu.my/79206/ http://www.ukm.my/jsm/pdf_files/SM-PDF-48-8-2019/05%20Rashidah%20Abdul%20Razak.pdf
_version_	1662753870316568576
spelling	my.iium.irep.792062020-03-10T07:44:41Z http://irep.iium.edu.my/79206/ Bactericidal efficacy of selected medicinal plant crude extracts and their fractions against common fish pathogens = Keberkesanan bakterisid ialah ekstrak mentah tumbuhan ubatan terpilih dan fraksinya terhadap patogen biasa ikan Abdul Razak, Rashidah Shariff, Mohamed Md. Yusoff, Fatimah Ismail, Intan Safinar S Agriculture (General) SH Aquaculture. Fisheries. Angling The emergence of new diseases and the increased use of antibiotics have led to the development of resistant bacterial strains. Thus, there is greater attention to seek new antibacterial agents from the natural sources for combating fish diseases in the aquaculture industry. The present study evaluated the bactericidal efficacy of crude methanolic and aqueous extracts from Polygonum chinense, Syzygium polyanthum, Premna foetida, Pimenta dioica, Brucea javanica, Vitex negundo, Alpinia conchigera and Clinacanthus nutans against Vibrio harveyi, Vibrio alginolyticus, Vibrio parahaemolyticus and Aeromonas hydrophila using disc diffusion method. The results showed that methanolic extracts of P. dioica, P. foetida and P. chinense, and aqueous extracts of P. dioica and S. polyanthum showed moderate to strong activity (10.8 to 17.2 mm) against all the tested bacteria. These five potential crude extracts were fractionated using liquid-liquid extraction method to obtain the methanol, dichloromethane and ethyl acetate fractions. Among the fractions, ethyl acetate fraction showed the highest activity against all tested bacteria, with minimum inhibition concentration (MIC) values between 0.625 and 10.000 mg/mL. In addition, the five potential crude extracts had low to moderate toxicity with LC50 >100 µg/ mL using brine shrimp cytotoxicity assays. The results of this study indicated that methanolic extracts of P. chinense and P. foetida that showed high bactericidal activity and low toxicity could be good potentials for use in fish culture. ****************************************************************************************** Kemunculan penyakit baharu dan peningkatan penggunaan antibiotik telah membawa kepada penghasilan strain bakteria yang rintang. Oleh itu, terdapat banyak perhatian untuk mencari agen antibakteria baru daripada sumber semula jadi bagi memerangi penyakit ikan dalam industri akuakultur. Kajian ini telah menguji keberkesanan bakterisid bagi ekstrak mentah metanolik dan akueus daripada Polygonum chinense, Syzygium polyanthum, Premna foetida, Pimenta dioica, Brucea javanica, Vitex negundo, Alphinia conchigera dan Clinacanthus nutans terhadap Vibrio harveyi, Vibrio alginolyticus, Vibrio parahaemolyticus dan Aeromonas hydrophila menggunakan kaedah penyebaran cakera. Hasil kajian telah menunjukkan ekstrak metanolik P. dioica, P. foetida dan P. chinense, dan ekstrak akueus P. dioica serta S. polyanthum mempunyai aktiviti antimikrob sederhana hingga kuat (10.8 hingga 17.2 mm) terhadap semua bakteria yang diuji. Kesemua lima ekstrak mentah yang berpotensi ini seterusnya difraksikan menggunakan kaedah pengekstrakan cecair-cecair untuk mendapatkan fraksi metanol, diklorometana dan etil asetat. Antara fraksi ini, fraksi etil asetat menunjukkan aktiviti tertinggi terhadap semua bakteria yang diuji dengan nilai kepekatan perencatan minimum (MIC) antara 0.625 hingga 10.000 mg/mL. Di samping itu, lima ekstrak mentah yang berpotensi ini mempunyai ketoksikan yang rendah hingga sederhana dengan LC50> 100 μg/mL menggunakan pengasaian kesitotoksikan udang brin. Hasil kajian ini menunjukkan bahawa ekstrak metanolik P. chinense dan P. foetida yang mempunyai aktiviti bakterisid tinggi dan ketoksikan rendah mempunyai potensi yang baik untuk digunakan dalam kultur ikan. Penerbit Universiti Kebangsaan Malaysia 2019 Article PeerReviewed application/pdf en http://irep.iium.edu.my/79206/1/79206_Bactericidal%20efficacy%20of%20selected%20medicinal.pdf application/pdf en http://irep.iium.edu.my/79206/2/79206_Bactericidal%20efficacy%20of%20selected%20medicinal_SCOPUS.pdf application/pdf en http://irep.iium.edu.my/79206/13/79206_Bactericidal%20Efficacy%20of%20Selected%20Medicinal_WOS.pdf Abdul Razak, Rashidah and Shariff, Mohamed and Md. Yusoff, Fatimah and Ismail, Intan Safinar (2019) Bactericidal efficacy of selected medicinal plant crude extracts and their fractions against common fish pathogens = Keberkesanan bakterisid ialah ekstrak mentah tumbuhan ubatan terpilih dan fraksinya terhadap patogen biasa ikan. Sains Malaysiana, 48 (8). pp. 1601-1608. ISSN 0126-6039 http://www.ukm.my/jsm/pdf_files/SM-PDF-48-8-2019/05%20Rashidah%20Abdul%20Razak.pdf 10.17576/jsm-2019-4808-05
score	13.211869

Bactericidal efficacy of selected medicinal plant crude extracts and their fractions against common fish pathogens = Keberkesanan bakterisid ialah ekstrak mentah tumbuhan ubatan terpilih dan fraksinya terhadap patogen biasa ikan

Similar Items