Prescription-level of tramadol utilisation at a tertiary hospital setting in Malaysia: changing trends over a 7-year follow-up period

INTRODUCTION It was reported in a previous study that tramadol was the most frequently prescribed analgesic in Malaysia’s hospital outpatient setting. However, little is known of its trends of prescribing. OBJECTIVES This study evaluated the trends of tramadol prescribing in Malaysia. ME...

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Main Authors: Alias, Nor Elina, Zin, Che Suraya, Mohamed Nazar, Nor Ilyani, Ab Rahman, Norny Syafinaz, Mohd Taufek, Nor Hidayah
Format: Conference or Workshop Item
Language:English
English
English
Published: 2019
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http://irep.iium.edu.my/76011/3/191015_posterICPRP.pdf
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spelling my.iium.irep.760112019-11-12T07:54:34Z http://irep.iium.edu.my/76011/ Prescription-level of tramadol utilisation at a tertiary hospital setting in Malaysia: changing trends over a 7-year follow-up period Alias, Nor Elina Zin, Che Suraya Mohamed Nazar, Nor Ilyani Ab Rahman, Norny Syafinaz Mohd Taufek, Nor Hidayah RM Therapeutics. Pharmacology INTRODUCTION It was reported in a previous study that tramadol was the most frequently prescribed analgesic in Malaysia’s hospital outpatient setting. However, little is known of its trends of prescribing. OBJECTIVES This study evaluated the trends of tramadol prescribing in Malaysia. METHOD This retrospective cross-sectional study was conducted using the prescription database of a tertiary hospital in Malaysia. All tramadol prescriptions in outpatient setting issued for adult patients aged ≥18 years old from 2010 to 2016 were included. The annual number of prescriptions and patients measured in repeat cross-sectional estimates for each year were evaluated. Descriptive statistics and linear trend analysis were applied using Stata version 15.1. RESULTS A total of 64594 tramadol prescriptions were prescribed for 40965 patients from 2010 to 2016. Prescriptions for tramadol increased by 52.7% from 7643 in 2010 to 11763 in 2016, with an average annual increment of 7.1%. The number of new patients prescribed with tramadol increased gradually throughout the study period (a 7.2% increase annually) with the majority (75.6%, n=30974) of them receiving one tramadol prescription. CONCLUSION: Tramadol prescribing increased gradually over a 7-year study period, with the majority of patients receiving only one prescription of tramadol - most likely indicating the use of tramadol for acute pain conditions. Further investigation on the indication and its clinical outcomes are required to ensure safe and rational use of tramadol. 2019-10-19 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/76011/1/191104_main%20page_program.pdf application/pdf en http://irep.iium.edu.my/76011/2/191104_elina_poster_program.pdf application/pdf en http://irep.iium.edu.my/76011/3/191015_posterICPRP.pdf Alias, Nor Elina and Zin, Che Suraya and Mohamed Nazar, Nor Ilyani and Ab Rahman, Norny Syafinaz and Mohd Taufek, Nor Hidayah (2019) Prescription-level of tramadol utilisation at a tertiary hospital setting in Malaysia: changing trends over a 7-year follow-up period. In: International Conference on Pharmaceutical Research and Pharmacy Practice cum 14th IIUM-MPS Pharmacy Scientific Conference (ICPRP 2019), 19-20th October 2019, Hotel Istana Kuala Lumpur. (Unpublished)
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
English
English
topic RM Therapeutics. Pharmacology
spellingShingle RM Therapeutics. Pharmacology
Alias, Nor Elina
Zin, Che Suraya
Mohamed Nazar, Nor Ilyani
Ab Rahman, Norny Syafinaz
Mohd Taufek, Nor Hidayah
Prescription-level of tramadol utilisation at a tertiary hospital setting in Malaysia: changing trends over a 7-year follow-up period
description INTRODUCTION It was reported in a previous study that tramadol was the most frequently prescribed analgesic in Malaysia’s hospital outpatient setting. However, little is known of its trends of prescribing. OBJECTIVES This study evaluated the trends of tramadol prescribing in Malaysia. METHOD This retrospective cross-sectional study was conducted using the prescription database of a tertiary hospital in Malaysia. All tramadol prescriptions in outpatient setting issued for adult patients aged ≥18 years old from 2010 to 2016 were included. The annual number of prescriptions and patients measured in repeat cross-sectional estimates for each year were evaluated. Descriptive statistics and linear trend analysis were applied using Stata version 15.1. RESULTS A total of 64594 tramadol prescriptions were prescribed for 40965 patients from 2010 to 2016. Prescriptions for tramadol increased by 52.7% from 7643 in 2010 to 11763 in 2016, with an average annual increment of 7.1%. The number of new patients prescribed with tramadol increased gradually throughout the study period (a 7.2% increase annually) with the majority (75.6%, n=30974) of them receiving one tramadol prescription. CONCLUSION: Tramadol prescribing increased gradually over a 7-year study period, with the majority of patients receiving only one prescription of tramadol - most likely indicating the use of tramadol for acute pain conditions. Further investigation on the indication and its clinical outcomes are required to ensure safe and rational use of tramadol.
format Conference or Workshop Item
author Alias, Nor Elina
Zin, Che Suraya
Mohamed Nazar, Nor Ilyani
Ab Rahman, Norny Syafinaz
Mohd Taufek, Nor Hidayah
author_facet Alias, Nor Elina
Zin, Che Suraya
Mohamed Nazar, Nor Ilyani
Ab Rahman, Norny Syafinaz
Mohd Taufek, Nor Hidayah
author_sort Alias, Nor Elina
title Prescription-level of tramadol utilisation at a tertiary hospital setting in Malaysia: changing trends over a 7-year follow-up period
title_short Prescription-level of tramadol utilisation at a tertiary hospital setting in Malaysia: changing trends over a 7-year follow-up period
title_full Prescription-level of tramadol utilisation at a tertiary hospital setting in Malaysia: changing trends over a 7-year follow-up period
title_fullStr Prescription-level of tramadol utilisation at a tertiary hospital setting in Malaysia: changing trends over a 7-year follow-up period
title_full_unstemmed Prescription-level of tramadol utilisation at a tertiary hospital setting in Malaysia: changing trends over a 7-year follow-up period
title_sort prescription-level of tramadol utilisation at a tertiary hospital setting in malaysia: changing trends over a 7-year follow-up period
publishDate 2019
url http://irep.iium.edu.my/76011/1/191104_main%20page_program.pdf
http://irep.iium.edu.my/76011/2/191104_elina_poster_program.pdf
http://irep.iium.edu.my/76011/3/191015_posterICPRP.pdf
http://irep.iium.edu.my/76011/
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score 13.211869