Antibacterial activities of piper sarmentosum (kaduk) methanolic extract
Piper sarmentosum or locally known as Kaduk is a tropical herbal plant that is well established for many traditional medicinal purposes. The antibacterial properties of methanolic extract for P. sarmentosum leaves have been investigated in this study. From the disc diffusion test, the methanolic e...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
UPM
2019
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/75600/1/ANTIBACTERIAL%20ACTIVITIES%20OF%20Piper%20sarmentosum%20%28KADUK%29%20METHANOLIC.pdf http://irep.iium.edu.my/75600/ http://psasir.upm.edu.my/id/eprint/67754/1/FP%202015%2088%20IR.pdf |
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| Summary: | Piper sarmentosum or locally known as Kaduk is a tropical herbal plant that is well established for many traditional
medicinal purposes. The antibacterial properties of methanolic extract for P. sarmentosum leaves have been
investigated in this study. From the disc diffusion test, the methanolic extract of P. sarmentosum was found to be
active against Gram-positive bacteria namely Staphylococcus saprophyticus (ATCC 15305) and Staphylococcus
aureus (ATCC 25923) with zone of inhibition at 17.1 and 11.3 mm, respectively. Meanwhile, the extract showed no
or minimal activity against Gram-negative bacteria (Klebsiella pneumoniae ATCC 700603, Pseudomonas aeroginosa
ATCC 27853, Enterococcus aerogenes ATCC 13048, Shigella flexneri IMR S 430/07 B, Salmonella typhimurium IMR S
974/05 B) as well as Gram-positive bacteria of Bacillus subtilis (IMR B145/11C). Accordingly, further study by
Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) were conducted on S.
saprophyticus and S. Aureus. The MIC value of methanolic extract for the tested S. saprophyticus and S. aureus were
both at 7.5 mg/mL. The MBC showed bacteriostatic for S. saprophyticus and S. aureus at 15 mg/mL. The result of this
study indicated that this Piper plant extract can be potential antibacterial agent in the future if the active component
can be identified. |
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