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Gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum

Sargassum polycystum is a brown seaweed, which has been reported to contain various phytoconstituents especially antimicrobial properties. However, the study on phytochemical components and biological activities of S. polycystum are yet fully understood. Therefore, the objectives of this study are t...

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Main Authors: Zamimi, Nurul Najwa, Ab. Halim, Noorhazayti, Darnis, Deny Susanti, Lestari, Widya, Md Mustafa, Md Muziman Syah
Format: Article
Language:English
English
Published: 2019
Subjects:
RM Therapeutics. Pharmacology
Online Access:http://irep.iium.edu.my/75520/1/Najwa%20et%20al.-2019-Gas%20chromatography-mass%20spectrometry.pdf
http://irep.iium.edu.my/75520/7/75520_Gas%20chromatography-mass%20spectrometry%20analysis%20of%20phytocomponents%20of%20sargassum%20polycystum_Scopus.pdf
http://irep.iium.edu.my/75520/
http://doi.org/10.26452/ijrps.v10i4.1533
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spelling my.iium.irep.755202022-04-20T06:25:02Z http://irep.iium.edu.my/75520/ Gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum Zamimi, Nurul Najwa Ab. Halim, Noorhazayti Darnis, Deny Susanti Lestari, Widya Md Mustafa, Md Muziman Syah RM Therapeutics. Pharmacology Sargassum polycystum is a brown seaweed, which has been reported to contain various phytoconstituents especially antimicrobial properties. However, the study on phytochemical components and biological activities of S. polycystum are yet fully understood. Therefore, the objectives of this study are to evaluate the best extraction solvents for S. polycystum and to determine the percentage of phytocomponents obtained in the n-hexane, dichloromethane (DCM) and methanol extracts of S. polycystum via Gas Chromatography-Mass Spectrometry (GC-MS) analysis. S. polycystum was collected from the coastal area of Sabah, Malaysia. After collection, it was rinsed, dried and extracted with n-hexane, DCM and methanol by soxhlet extraction. The fatty acid compounds (FAME) analysis was done using The Perkin Elmer Turbo Mass Spectrometer. This study showed that methanol is the most efficient solvent as it produced the highest extraction yield with 3.83%, followed by n-hexane with 1.69% and lastly DCM with 0.59% in S. polycystum. On top of that, this study has found 19 phytocomponents in all extraction methods of S. polycystum, which have been proven to possess antibacterial constituents such as palmitic acid, myristic acid, oleic acid, pentadecanoic acid and behenic acid as assessed by GC-MS analysis. 2019 Article PeerReviewed application/pdf en http://irep.iium.edu.my/75520/1/Najwa%20et%20al.-2019-Gas%20chromatography-mass%20spectrometry.pdf application/pdf en http://irep.iium.edu.my/75520/7/75520_Gas%20chromatography-mass%20spectrometry%20analysis%20of%20phytocomponents%20of%20sargassum%20polycystum_Scopus.pdf Zamimi, Nurul Najwa and Ab. Halim, Noorhazayti and Darnis, Deny Susanti and Lestari, Widya and Md Mustafa, Md Muziman Syah (2019) Gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum. International Journal of Research in Pharmaceutical Sciences, 10 (4). pp. 2705-2710. ISSN 0975-7538 http://doi.org/10.26452/ijrps.v10i4.1533 doi:10.26452/ijrps.v10i4.1533
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
English
topic RM Therapeutics. Pharmacology
spellingShingle RM Therapeutics. Pharmacology
Zamimi, Nurul Najwa
Ab. Halim, Noorhazayti
Darnis, Deny Susanti
Lestari, Widya
Md Mustafa, Md Muziman Syah
Gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum
description Sargassum polycystum is a brown seaweed, which has been reported to contain various phytoconstituents especially antimicrobial properties. However, the study on phytochemical components and biological activities of S. polycystum are yet fully understood. Therefore, the objectives of this study are to evaluate the best extraction solvents for S. polycystum and to determine the percentage of phytocomponents obtained in the n-hexane, dichloromethane (DCM) and methanol extracts of S. polycystum via Gas Chromatography-Mass Spectrometry (GC-MS) analysis. S. polycystum was collected from the coastal area of Sabah, Malaysia. After collection, it was rinsed, dried and extracted with n-hexane, DCM and methanol by soxhlet extraction. The fatty acid compounds (FAME) analysis was done using The Perkin Elmer Turbo Mass Spectrometer. This study showed that methanol is the most efficient solvent as it produced the highest extraction yield with 3.83%, followed by n-hexane with 1.69% and lastly DCM with 0.59% in S. polycystum. On top of that, this study has found 19 phytocomponents in all extraction methods of S. polycystum, which have been proven to possess antibacterial constituents such as palmitic acid, myristic acid, oleic acid, pentadecanoic acid and behenic acid as assessed by GC-MS analysis.
format Article
author Zamimi, Nurul Najwa
Ab. Halim, Noorhazayti
Darnis, Deny Susanti
Lestari, Widya
Md Mustafa, Md Muziman Syah
author_facet Zamimi, Nurul Najwa
Ab. Halim, Noorhazayti
Darnis, Deny Susanti
Lestari, Widya
Md Mustafa, Md Muziman Syah
author_sort Zamimi, Nurul Najwa
title Gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum
title_short Gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum
title_full Gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum
title_fullStr Gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum
title_full_unstemmed Gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum
title_sort gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum
publishDate 2019
url http://irep.iium.edu.my/75520/1/Najwa%20et%20al.-2019-Gas%20chromatography-mass%20spectrometry.pdf
http://irep.iium.edu.my/75520/7/75520_Gas%20chromatography-mass%20spectrometry%20analysis%20of%20phytocomponents%20of%20sargassum%20polycystum_Scopus.pdf
http://irep.iium.edu.my/75520/
http://doi.org/10.26452/ijrps.v10i4.1533
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score 13.211869

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