Cover Image

The antimicrobial effect of flax seed on pseudomonas aeruginosa

Flaxseed comes from the flax plant (Linum usitatissimum), which has been cultivated for domestic use since prehistoric times. Pseudomonas aeruginosa is a Gram-negative bacterium has the ability to survive in adverse environments and develop multiple antibiotic resistance mechanisms. This study aims...

Full description

Saved in:
Bibliographic Details
Main Authors: Mohamed Yusoff, Nurul Fatihah, Mustafa Al-Ahmad, Basma Ezzat, Subramaniam, Pram Kumar, Mustafa, Nazih Shaban, Kashmola, Muhanad Ali Hamdon, Mokhtar@Makhtar, Khairani Idah, Darnis, Deny Susanti
Format: Article
Language:English
Published: 2019
Subjects:
RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works
Online Access:http://irep.iium.edu.my/74782/1/74782_The%20antimicrobial%20effect%20of%20flax.pdf
http://irep.iium.edu.my/74782/
https://www.wjpps.com/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.iium.irep.74782
record_format dspace
spelling my.iium.irep.747822020-02-04T07:13:45Z http://irep.iium.edu.my/74782/ The antimicrobial effect of flax seed on pseudomonas aeruginosa Mohamed Yusoff, Nurul Fatihah Mustafa Al-Ahmad, Basma Ezzat Subramaniam, Pram Kumar Mustafa, Nazih Shaban Kashmola, Muhanad Ali Hamdon Mokhtar@Makhtar, Khairani Idah Darnis, Deny Susanti RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works Flaxseed comes from the flax plant (Linum usitatissimum), which has been cultivated for domestic use since prehistoric times. Pseudomonas aeruginosa is a Gram-negative bacterium has the ability to survive in adverse environments and develop multiple antibiotic resistance mechanisms. This study aims to evaluate the susceptibility of Pseudomonas aeruginosa (P. aeruginosa) In-vitro to the ethanolic extract obtained from flax seed. This is a laboratory experimental in vitro study using P. aeruginosa cultured in nutrient agar. The pathogen then was inoculated in nutrient based broth and incubated for 24hours. Flaxseed extract efficacy was tested by measurement of the zone of inhibition. The result of the extracts antimicrobial activities were compared with streptomycin as positive control and DMSO as negative control. The statistical analysis was done by using GraphPad PRISM version 6. There is positive antibacterial effects of flaxseed extract against Pseudomonas aeruginosa and it was comparable in efficacy to that of Streptomycin. This study concludes that flaxseed extract can help in inhibiting Pseudomonas aeruginosa activity. The implication of this result will be useful in propagating the use of natural based product as therapeutic drug against the chemical synthetic products. The results of the present study scientifically validate the inhibitory capacity of Linum usitatissimum as antibiotic against one of the most resistant pathogens and contribute towards the development of new treatment options based on natural products. 2019-09-01 Article PeerReviewed application/pdf en http://irep.iium.edu.my/74782/1/74782_The%20antimicrobial%20effect%20of%20flax.pdf Mohamed Yusoff, Nurul Fatihah and Mustafa Al-Ahmad, Basma Ezzat and Subramaniam, Pram Kumar and Mustafa, Nazih Shaban and Kashmola, Muhanad Ali Hamdon and Mokhtar@Makhtar, Khairani Idah and Darnis, Deny Susanti (2019) The antimicrobial effect of flax seed on pseudomonas aeruginosa. World Journal of Pharmacy and Pharmaceutical Sciences, 8 (9). pp. 629-642. ISSN 2278 – 4357 https://www.wjpps.com/ 10.20959/wjpps20199-14572
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works
spellingShingle RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works
Mohamed Yusoff, Nurul Fatihah
Mustafa Al-Ahmad, Basma Ezzat
Subramaniam, Pram Kumar
Mustafa, Nazih Shaban
Kashmola, Muhanad Ali Hamdon
Mokhtar@Makhtar, Khairani Idah
Darnis, Deny Susanti
The antimicrobial effect of flax seed on pseudomonas aeruginosa
description Flaxseed comes from the flax plant (Linum usitatissimum), which has been cultivated for domestic use since prehistoric times. Pseudomonas aeruginosa is a Gram-negative bacterium has the ability to survive in adverse environments and develop multiple antibiotic resistance mechanisms. This study aims to evaluate the susceptibility of Pseudomonas aeruginosa (P. aeruginosa) In-vitro to the ethanolic extract obtained from flax seed. This is a laboratory experimental in vitro study using P. aeruginosa cultured in nutrient agar. The pathogen then was inoculated in nutrient based broth and incubated for 24hours. Flaxseed extract efficacy was tested by measurement of the zone of inhibition. The result of the extracts antimicrobial activities were compared with streptomycin as positive control and DMSO as negative control. The statistical analysis was done by using GraphPad PRISM version 6. There is positive antibacterial effects of flaxseed extract against Pseudomonas aeruginosa and it was comparable in efficacy to that of Streptomycin. This study concludes that flaxseed extract can help in inhibiting Pseudomonas aeruginosa activity. The implication of this result will be useful in propagating the use of natural based product as therapeutic drug against the chemical synthetic products. The results of the present study scientifically validate the inhibitory capacity of Linum usitatissimum as antibiotic against one of the most resistant pathogens and contribute towards the development of new treatment options based on natural products.
format Article
author Mohamed Yusoff, Nurul Fatihah
Mustafa Al-Ahmad, Basma Ezzat
Subramaniam, Pram Kumar
Mustafa, Nazih Shaban
Kashmola, Muhanad Ali Hamdon
Mokhtar@Makhtar, Khairani Idah
Darnis, Deny Susanti
author_facet Mohamed Yusoff, Nurul Fatihah
Mustafa Al-Ahmad, Basma Ezzat
Subramaniam, Pram Kumar
Mustafa, Nazih Shaban
Kashmola, Muhanad Ali Hamdon
Mokhtar@Makhtar, Khairani Idah
Darnis, Deny Susanti
author_sort Mohamed Yusoff, Nurul Fatihah
title The antimicrobial effect of flax seed on pseudomonas aeruginosa
title_short The antimicrobial effect of flax seed on pseudomonas aeruginosa
title_full The antimicrobial effect of flax seed on pseudomonas aeruginosa
title_fullStr The antimicrobial effect of flax seed on pseudomonas aeruginosa
title_full_unstemmed The antimicrobial effect of flax seed on pseudomonas aeruginosa
title_sort antimicrobial effect of flax seed on pseudomonas aeruginosa
publishDate 2019
url http://irep.iium.edu.my/74782/1/74782_The%20antimicrobial%20effect%20of%20flax.pdf
http://irep.iium.edu.my/74782/
https://www.wjpps.com/
_version_ 1662753744961404928
score 13.211869

Similar Items