Engineering human epidermal growth receptor 2‑Targeting hepatitis B virus core nanoparticles for siRNA delivery in vitro and in vivo
Hepatitis B virus core (HBc) particles acquire the capacity to disassemble and reassemble in a controlled manner, allowing entrapment and delivery of drugs and macromolecules to cells. HBc particles are made of 180−240 copies of 21 kDa protein monomers, assembled into 30−34 nm diameter icosahedral...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society
2018
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/64619/1/acsanm.8b00480.pdf http://irep.iium.edu.my/64619/ https://pubs.acs.org/doi/pdf/10.1021/acsanm.8b00480 |
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