Tumor Necrosis factor–Nelated Apoptosis‐Inducing Ligand (TRAIL) Promotes Angiogenesis and Ischemia‐Induced Neovascularization Via NADPH Oxidase 4 (NOX4) and Nitric Oxide–Dependent Mechanisms
Background Tumor necrosis factor–related apoptosis‐inducing ligand (TRAIL) has the ability to inhibit angiogenesis by inducing endothelial cell death, as well as being able to promote pro‐angiogenic activity in vitro. These seemingly opposite effects make its role in ischemic disease unclear. Using...
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Main Authors: | Di Bartolo, Belinda Ann, Peta Cartland, Siân, Prado‐Lourenco, Leonel, Scott Griffith, Thomas, Gentile, Carmine, Ravindran, Jayant, Md. Azahri, Nor Saadah, Thai, Thuan, Yeung, Amanda Wing Shee, Thomas, Shane Ross, Kavurma, Mary Meltem |
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Format: | Article |
Language: | English |
Published: |
American Heart Association
2015
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Subjects: | |
Online Access: | http://irep.iium.edu.my/62221/7/62221_Tumor%20Necrosis%20factor%E2%80%93Nelated%20Apoptosis%E2%80%90Inducing%20Ligand.pdf http://irep.iium.edu.my/62221/ https://www.ahajournals.org/journal/jaha |
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