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Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet

Supercritical fluid extraction (SFE) using carbon dioxide (CO2) and liquid CO2 using Soxhlet (CO2-Soxhlet) extraction were employed to extract three (3) antidiabetic compounds viz. stigmasterol, quercetin, and avicularin from Mimosa pudica. Various extraction parameters were studied. Extracts were a...

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Main Authors: Tunna, Tasnuva Sarwar, Sarker, Md. Zaidul Islam, Ghafoor, Kashif, Ferdosh, Sahena, Md. Jaffri, Juliana, AL-Juhaımı, Fahad Y.I., Ali, Md Eaqub, Akanda, Md Jahurul Haque, Awal, Md Shihabul, Ahmed, Qamar Uddin, Selamat, Jinap
Format: Article
Language:English
English
English
Published: http://www.tandfonline.com/loi/lsst20 2018
Subjects:
RS192 Materia Medica-Pharmaceutical Technology
Online Access:http://irep.iium.edu.my/60532/1/SST-Tunna-Zaidul-2017.pdf
http://irep.iium.edu.my/60532/7/60532_Enrichment%2C%20in%20vitro%2C%20and%20quantification_scopus.pdf
http://irep.iium.edu.my/60532/13/60532_Enrichment%2C%20in%20vitro%2C%20and%20quantification%20_WoS.pdf
http://irep.iium.edu.my/60532/
http://www.tandfonline.com/loi/lsst20
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spelling my.iium.irep.605322022-12-09T02:33:06Z http://irep.iium.edu.my/60532/ Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet Tunna, Tasnuva Sarwar Sarker, Md. Zaidul Islam Ghafoor, Kashif Ferdosh, Sahena Md. Jaffri, Juliana AL-Juhaımı, Fahad Y.I. Ali, Md Eaqub Akanda, Md Jahurul Haque Awal, Md Shihabul Ahmed, Qamar Uddin Selamat, Jinap RS192 Materia Medica-Pharmaceutical Technology Supercritical fluid extraction (SFE) using carbon dioxide (CO2) and liquid CO2 using Soxhlet (CO2-Soxhlet) extraction were employed to extract three (3) antidiabetic compounds viz. stigmasterol, quercetin, and avicularin from Mimosa pudica. Various extraction parameters were studied. Extracts were analyzed pharmacologically, qualitatively and quantitatively to ascertain enrichment levels. All three antidiabetic compounds were effectively enriched under optimized conditions of temperature 60°C, pressure 40 MPa, co-solvent ratio 30%, and CO2 flow rate of 5 ml min−1. SFE was found to be the better method for enrichment of the antidiabetic compounds than the CO2-Soxhlet method. Extraction conditions were seen to affect the enrichment of desired compounds. http://www.tandfonline.com/loi/lsst20 2018-01-22 Article PeerReviewed application/pdf en http://irep.iium.edu.my/60532/1/SST-Tunna-Zaidul-2017.pdf application/pdf en http://irep.iium.edu.my/60532/7/60532_Enrichment%2C%20in%20vitro%2C%20and%20quantification_scopus.pdf application/pdf en http://irep.iium.edu.my/60532/13/60532_Enrichment%2C%20in%20vitro%2C%20and%20quantification%20_WoS.pdf Tunna, Tasnuva Sarwar and Sarker, Md. Zaidul Islam and Ghafoor, Kashif and Ferdosh, Sahena and Md. Jaffri, Juliana and AL-Juhaımı, Fahad Y.I. and Ali, Md Eaqub and Akanda, Md Jahurul Haque and Awal, Md Shihabul and Ahmed, Qamar Uddin and Selamat, Jinap (2018) Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet. Separation Science and Technology, 53 (2). pp. 243-260. ISSN 0149-6395 E-ISSN 1520-5754 http://www.tandfonline.com/loi/lsst20 10.1080/01496395.2017.1384015
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
English
English
topic RS192 Materia Medica-Pharmaceutical Technology
spellingShingle RS192 Materia Medica-Pharmaceutical Technology
Tunna, Tasnuva Sarwar
Sarker, Md. Zaidul Islam
Ghafoor, Kashif
Ferdosh, Sahena
Md. Jaffri, Juliana
AL-Juhaımı, Fahad Y.I.
Ali, Md Eaqub
Akanda, Md Jahurul Haque
Awal, Md Shihabul
Ahmed, Qamar Uddin
Selamat, Jinap
Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet
description Supercritical fluid extraction (SFE) using carbon dioxide (CO2) and liquid CO2 using Soxhlet (CO2-Soxhlet) extraction were employed to extract three (3) antidiabetic compounds viz. stigmasterol, quercetin, and avicularin from Mimosa pudica. Various extraction parameters were studied. Extracts were analyzed pharmacologically, qualitatively and quantitatively to ascertain enrichment levels. All three antidiabetic compounds were effectively enriched under optimized conditions of temperature 60°C, pressure 40 MPa, co-solvent ratio 30%, and CO2 flow rate of 5 ml min−1. SFE was found to be the better method for enrichment of the antidiabetic compounds than the CO2-Soxhlet method. Extraction conditions were seen to affect the enrichment of desired compounds.
format Article
author Tunna, Tasnuva Sarwar
Sarker, Md. Zaidul Islam
Ghafoor, Kashif
Ferdosh, Sahena
Md. Jaffri, Juliana
AL-Juhaımı, Fahad Y.I.
Ali, Md Eaqub
Akanda, Md Jahurul Haque
Awal, Md Shihabul
Ahmed, Qamar Uddin
Selamat, Jinap
author_facet Tunna, Tasnuva Sarwar
Sarker, Md. Zaidul Islam
Ghafoor, Kashif
Ferdosh, Sahena
Md. Jaffri, Juliana
AL-Juhaımı, Fahad Y.I.
Ali, Md Eaqub
Akanda, Md Jahurul Haque
Awal, Md Shihabul
Ahmed, Qamar Uddin
Selamat, Jinap
author_sort Tunna, Tasnuva Sarwar
title Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet
title_short Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet
title_full Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet
title_fullStr Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet
title_full_unstemmed Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet
title_sort enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed mimosa pudica using supercritical co2 and co2-soxhlet
publisher http://www.tandfonline.com/loi/lsst20
publishDate 2018
url http://irep.iium.edu.my/60532/1/SST-Tunna-Zaidul-2017.pdf
http://irep.iium.edu.my/60532/7/60532_Enrichment%2C%20in%20vitro%2C%20and%20quantification_scopus.pdf
http://irep.iium.edu.my/60532/13/60532_Enrichment%2C%20in%20vitro%2C%20and%20quantification%20_WoS.pdf
http://irep.iium.edu.my/60532/
http://www.tandfonline.com/loi/lsst20
_version_ 1752146272864698368
score 13.211869

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