Principal component analysis application on flavonoids characterization

Flavonoid is one of the bioactive compounds that are currently used in pharmaceutical and medicinal industries due to their health benefit. The focus of current research is mainly on the extraction and isolation of bioactive compounds; however non to date has explored on the identification of fla...

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Bibliographic Details
Main Authors: Che Noh, Che Hafizah, Mohamed Azmin, Nor Fadhillah, Amid, Azura
Format: Article
Language:English
Published: Thomson Reuters 2017
Subjects:
Online Access:http://irep.iium.edu.my/59897/1/ASTESJ_PCA%20Application%20on%20Flavonoids%20Characterization.pdf
http://irep.iium.edu.my/59897/
https://astesj.com/v02/i03/p56/
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Summary:Flavonoid is one of the bioactive compounds that are currently used in pharmaceutical and medicinal industries due to their health benefit. The focus of current research is mainly on the extraction and isolation of bioactive compounds; however non to date has explored on the identification of flavonoids classes under the Fourier Transform Infrared spectroscopy (FTIR). This gap presents an opportunity for the application of statistical analysis which can identify the distinct wavenumbers range of flavone, flavanone and flavonol for their characterization in the FTIR spectrum. Development of algorithm based on principal component analysis (PCA) for the analysis and identification of flavonoids classes based on FTIR spectrum was introduced. Based on the results, five wavenumbers ranges have been identified as the distinct characteristics of flavonol, flavone and flavanone hence used for their identification.