Visceral adiposity index in older adults:Associations with physical functions and cardiometabolic risk

Studies have shown that visceral adiposity index (VAI) reflects metabolic disturbances and cardiometabolic risk, both of which are associated with lower physical functions. This study aimed to evaluate the associations of VAI with physical functions (i.e. cardiorespiratory fitness, balance, grip str...

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Main Authors: Mohamad Fauzi, Nor Farah, Che Hasan, Muhammad Kamil, Henry Joseph, Leonard
Format: Article
Language:English
Published: Wiley Online Library 2014
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Online Access:http://irep.iium.edu.my/59766/8/59766_Visceral%20adiposity%20index%20in%20older_abstract.pdf
http://irep.iium.edu.my/59766/
http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1467-789X/issues?activeYear=2014
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spelling my.iium.irep.597662017-12-07T09:50:41Z http://irep.iium.edu.my/59766/ Visceral adiposity index in older adults:Associations with physical functions and cardiometabolic risk Mohamad Fauzi, Nor Farah Che Hasan, Muhammad Kamil Henry Joseph, Leonard Q Science (General) RT Nursing RT71 Study and Teaching Studies have shown that visceral adiposity index (VAI) reflects metabolic disturbances and cardiometabolic risk, both of which are associated with lower physical functions. This study aimed to evaluate the associations of VAI with physical functions (i.e. cardiorespiratory fitness, balance, grip strength) and cardiometabolic parameters in older adults. Sixty, physically inactive men and women (n male = 35, age: 60.2 ± 4.4 years, BMI: 28.8 ± 4.6 kg/m2), underwent (1) anthropometric measurements; (2) 6-minute walk test, timed up-and-go and hand grip tests; (3) assessment of plasma insulin, glucose, triglycerides, HDL, adiponectin, and highsensitivity C-reactive protein (hs-CRP). VAI was estimated using anthropometric (BMI and waist circumference) and biochemical (triglycerides and HDL) parameters. Insulin resistance was calculated as HOMA-IR index. Partial correlations analysis controlled for gender demonstrated positive associations for VAI with insulin resistance (r = 0.658, p < 0.001) and hs-CRP (r = 0.325, p = 0.012). No association between VAI and physical function parameters was observed. In addition, waist circumference was inversely correlated with plasma adiponectin (r = −0.297, p = 0.023). Multivariate regression analysis revealed that only insulin resistance was an independent predictor of VAI. This study suggests that VAI is a strong indicator of deterioration in insulin sensitivity, and is associated with hs-CRP but not physical functions in older adults. Wiley Online Library 2014 Article REM application/pdf en http://irep.iium.edu.my/59766/8/59766_Visceral%20adiposity%20index%20in%20older_abstract.pdf Mohamad Fauzi, Nor Farah and Che Hasan, Muhammad Kamil and Henry Joseph, Leonard (2014) Visceral adiposity index in older adults:Associations with physical functions and cardiometabolic risk. Obesity Reviews, 15 (Supplementary 2). p. 70. ISSN 1467-789X http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1467-789X/issues?activeYear=2014 10.1111/obr.12149
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic Q Science (General)
RT Nursing
RT71 Study and Teaching
spellingShingle Q Science (General)
RT Nursing
RT71 Study and Teaching
Mohamad Fauzi, Nor Farah
Che Hasan, Muhammad Kamil
Henry Joseph, Leonard
Visceral adiposity index in older adults:Associations with physical functions and cardiometabolic risk
description Studies have shown that visceral adiposity index (VAI) reflects metabolic disturbances and cardiometabolic risk, both of which are associated with lower physical functions. This study aimed to evaluate the associations of VAI with physical functions (i.e. cardiorespiratory fitness, balance, grip strength) and cardiometabolic parameters in older adults. Sixty, physically inactive men and women (n male = 35, age: 60.2 ± 4.4 years, BMI: 28.8 ± 4.6 kg/m2), underwent (1) anthropometric measurements; (2) 6-minute walk test, timed up-and-go and hand grip tests; (3) assessment of plasma insulin, glucose, triglycerides, HDL, adiponectin, and highsensitivity C-reactive protein (hs-CRP). VAI was estimated using anthropometric (BMI and waist circumference) and biochemical (triglycerides and HDL) parameters. Insulin resistance was calculated as HOMA-IR index. Partial correlations analysis controlled for gender demonstrated positive associations for VAI with insulin resistance (r = 0.658, p < 0.001) and hs-CRP (r = 0.325, p = 0.012). No association between VAI and physical function parameters was observed. In addition, waist circumference was inversely correlated with plasma adiponectin (r = −0.297, p = 0.023). Multivariate regression analysis revealed that only insulin resistance was an independent predictor of VAI. This study suggests that VAI is a strong indicator of deterioration in insulin sensitivity, and is associated with hs-CRP but not physical functions in older adults.
format Article
author Mohamad Fauzi, Nor Farah
Che Hasan, Muhammad Kamil
Henry Joseph, Leonard
author_facet Mohamad Fauzi, Nor Farah
Che Hasan, Muhammad Kamil
Henry Joseph, Leonard
author_sort Mohamad Fauzi, Nor Farah
title Visceral adiposity index in older adults:Associations with physical functions and cardiometabolic risk
title_short Visceral adiposity index in older adults:Associations with physical functions and cardiometabolic risk
title_full Visceral adiposity index in older adults:Associations with physical functions and cardiometabolic risk
title_fullStr Visceral adiposity index in older adults:Associations with physical functions and cardiometabolic risk
title_full_unstemmed Visceral adiposity index in older adults:Associations with physical functions and cardiometabolic risk
title_sort visceral adiposity index in older adults:associations with physical functions and cardiometabolic risk
publisher Wiley Online Library
publishDate 2014
url http://irep.iium.edu.my/59766/8/59766_Visceral%20adiposity%20index%20in%20older_abstract.pdf
http://irep.iium.edu.my/59766/
http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1467-789X/issues?activeYear=2014
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score 13.211869