Synthesis of new 3-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-benzenesulfonamides with strong inhibition properties against the tumor associated carbonic anhydrases IX and XII
We report a series of novel metanilamide-based derivatives 3a–q bearing the 2-mercapto-4-oxo-4H-quinazolin-3-yl moiety as tail. All compounds were synthesized by means of straightforward condensation procedures and were investigated in vitro for their inhibition potency against the human (h) carboni...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English English English |
| Published: |
Elsevier Ltd
2017
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/57250/3/57250_Synthesis%20of%20new%203-%282-mercapto_WOS.pdf http://irep.iium.edu.my/57250/19/57250_Synthesis%20of%20new%203-%282-mercapto-4-oxo-4H-quinazolin-3-yl%29.pdf http://irep.iium.edu.my/57250/25/57250_Synthesis%20of%20new%203-%282-mercapto-4-oxo-4H-quinazolin-3-yl%29-benzenesulfonamides_SCOPUS.pdf http://irep.iium.edu.my/57250/ http://www.sciencedirect.com/science/article/pii/S0968089617304443 |
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http://irep.iium.edu.my/57250/3/57250_Synthesis%20of%20new%203-%282-mercapto_WOS.pdfhttp://irep.iium.edu.my/57250/19/57250_Synthesis%20of%20new%203-%282-mercapto-4-oxo-4H-quinazolin-3-yl%29.pdf
http://irep.iium.edu.my/57250/25/57250_Synthesis%20of%20new%203-%282-mercapto-4-oxo-4H-quinazolin-3-yl%29-benzenesulfonamides_SCOPUS.pdf
http://irep.iium.edu.my/57250/
http://www.sciencedirect.com/science/article/pii/S0968089617304443