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Synthesis and characterization of spermidine containing sulphur

Studies in compound containing sulphur and the polyamine transport system is beneficial in oncology as both affect cancer cells. Compounds containing sulphur such as organosulphur are known for their anti-cancer properties. The polyamine transport system however is known for its ability to interact...

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Main Authors: Sahabudin, Adzly Hairee, How, Fiona Ni Foong, Abdul Ghani, Radiah
Format: Conference or Workshop Item
Language:English
Published: Penerbit UMT, Universiti Malaysia Terengganu (UMT) 2016
Subjects:
QD Chemistry
Online Access:http://irep.iium.edu.my/53900/1/53900_Synthesize%20and%20Characterization%20of%20Spermidine.pdf
http://irep.iium.edu.my/53900/
http://umtas2016.umt.edu.my/?page_id=210
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spelling my.iium.irep.539002017-05-17T06:26:52Z http://irep.iium.edu.my/53900/ Synthesis and characterization of spermidine containing sulphur Sahabudin, Adzly Hairee How, Fiona Ni Foong Abdul Ghani, Radiah QD Chemistry Studies in compound containing sulphur and the polyamine transport system is beneficial in oncology as both affect cancer cells. Compounds containing sulphur such as organosulphur are known for their anti-cancer properties. The polyamine transport system however is known for its ability to interact with cancer cells directly. By adding sulphur to known natural polyamine, the resulting compound is anticipated to retain both properties. One of the widely used of polyamine moiety is used as the cell delivery vector to transport sulphur to the targeted cancer cells. In this study, the spermidine containing sulphur was synthesized by adding carbon disulphide atoms to spermidine atom. The compound was then characterized and analyzed to determine its physiochemical properties and chemical structure. Determination on the characteristic and chemical structure of the compounds were carried out using various techniques such Fourier transformed infrared spectroscopy, thin layer chromatography and gas chromatography mass spectroscopy. Penerbit UMT, Universiti Malaysia Terengganu (UMT) 2016-11-31 Conference or Workshop Item REM application/pdf en http://irep.iium.edu.my/53900/1/53900_Synthesize%20and%20Characterization%20of%20Spermidine.pdf Sahabudin, Adzly Hairee and How, Fiona Ni Foong and Abdul Ghani, Radiah (2016) Synthesis and characterization of spermidine containing sulphur. In: 13th Universiti Malaysia Terengganu International Annual Symposium on Sustainability Science and Management (UMTAS 2016), 13th-15th Dec. 2016, Kuala Terengganu. http://umtas2016.umt.edu.my/?page_id=210
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic QD Chemistry
spellingShingle QD Chemistry
Sahabudin, Adzly Hairee
How, Fiona Ni Foong
Abdul Ghani, Radiah
Synthesis and characterization of spermidine containing sulphur
description Studies in compound containing sulphur and the polyamine transport system is beneficial in oncology as both affect cancer cells. Compounds containing sulphur such as organosulphur are known for their anti-cancer properties. The polyamine transport system however is known for its ability to interact with cancer cells directly. By adding sulphur to known natural polyamine, the resulting compound is anticipated to retain both properties. One of the widely used of polyamine moiety is used as the cell delivery vector to transport sulphur to the targeted cancer cells. In this study, the spermidine containing sulphur was synthesized by adding carbon disulphide atoms to spermidine atom. The compound was then characterized and analyzed to determine its physiochemical properties and chemical structure. Determination on the characteristic and chemical structure of the compounds were carried out using various techniques such Fourier transformed infrared spectroscopy, thin layer chromatography and gas chromatography mass spectroscopy.
format Conference or Workshop Item
author Sahabudin, Adzly Hairee
How, Fiona Ni Foong
Abdul Ghani, Radiah
author_facet Sahabudin, Adzly Hairee
How, Fiona Ni Foong
Abdul Ghani, Radiah
author_sort Sahabudin, Adzly Hairee
title Synthesis and characterization of spermidine containing sulphur
title_short Synthesis and characterization of spermidine containing sulphur
title_full Synthesis and characterization of spermidine containing sulphur
title_fullStr Synthesis and characterization of spermidine containing sulphur
title_full_unstemmed Synthesis and characterization of spermidine containing sulphur
title_sort synthesis and characterization of spermidine containing sulphur
publisher Penerbit UMT, Universiti Malaysia Terengganu (UMT)
publishDate 2016
url http://irep.iium.edu.my/53900/1/53900_Synthesize%20and%20Characterization%20of%20Spermidine.pdf
http://irep.iium.edu.my/53900/
http://umtas2016.umt.edu.my/?page_id=210
_version_ 1643614439924039680
score 13.211869

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