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Effect of some parameters on the extraction process of antifungal peptides from Supermeal worm, Zophobas morio (Fabricius)

Acidified isopropanol extract of whole body larvae of Zophobas morio (Fabricius), which contains peptides, has been shown to exhibit an inhibitory effect towards fungal growth. The larvae, commonly known as supermeal worm are cheap and easily maintained. To make the extraction even more cost effec...

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Main Authors: Faruck, Mohammad Omer, Yusof, Faridah, Chowdhury , Silvia
Format: Conference or Workshop Item
Language:English
Published: Kulliyah of Engineering, International Islamic University Malaysia 2016
Subjects:
QP Physiology
TP248.13 Biotechnology
Online Access:http://irep.iium.edu.my/51733/1/51733.pdf
http://irep.iium.edu.my/51733/
http://www.iium.edu.my/icbioe/2016/
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spelling my.iium.irep.517332016-08-22T01:50:19Z http://irep.iium.edu.my/51733/ Effect of some parameters on the extraction process of antifungal peptides from Supermeal worm, Zophobas morio (Fabricius) Faruck, Mohammad Omer Yusof, Faridah Chowdhury , Silvia QP Physiology TP248.13 Biotechnology Acidified isopropanol extract of whole body larvae of Zophobas morio (Fabricius), which contains peptides, has been shown to exhibit an inhibitory effect towards fungal growth. The larvae, commonly known as supermeal worm are cheap and easily maintained. To make the extraction even more cost effective, it is pertinent to maximize the extraction yield and to optimize the extraction process. The aim of this study is to use the One-Factor-At-a-Time (OFAT) strategy to determine the maximum values of the process parameters for the extraction of antifungal peptides, where these values can later be used in the design to optimize the extraction process. Based on importance, three parameters were selected, namely, initial homogenization temperature, homogenization time and solid (g) to solvent (ml) ratio. Maximum inhibition to fungal growth was found when the extraction was carried out as follows; using initial homogenization temperature of 4°C, homogenization time of 5 minutes and a solid (g) to solvent (ml) ratio of 3.5:1. The peptide extract displayed different degree of antifungal effect towards four selected fungi, Aspergillus niger, Microsporum canis, Candida albicans and Blastomyces dermatitidsis. Kulliyah of Engineering, International Islamic University Malaysia 2016 Conference or Workshop Item REM application/pdf en http://irep.iium.edu.my/51733/1/51733.pdf Faruck, Mohammad Omer and Yusof, Faridah and Chowdhury , Silvia (2016) Effect of some parameters on the extraction process of antifungal peptides from Supermeal worm, Zophobas morio (Fabricius). In: 4th International Conference on Biotechnology Engineering 2016 (ICBioE 2016), 25th-27th July 2016, Kuala Lumpur. http://www.iium.edu.my/icbioe/2016/
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic QP Physiology
TP248.13 Biotechnology
spellingShingle QP Physiology
TP248.13 Biotechnology
Faruck, Mohammad Omer
Yusof, Faridah
Chowdhury , Silvia
Effect of some parameters on the extraction process of antifungal peptides from Supermeal worm, Zophobas morio (Fabricius)
description Acidified isopropanol extract of whole body larvae of Zophobas morio (Fabricius), which contains peptides, has been shown to exhibit an inhibitory effect towards fungal growth. The larvae, commonly known as supermeal worm are cheap and easily maintained. To make the extraction even more cost effective, it is pertinent to maximize the extraction yield and to optimize the extraction process. The aim of this study is to use the One-Factor-At-a-Time (OFAT) strategy to determine the maximum values of the process parameters for the extraction of antifungal peptides, where these values can later be used in the design to optimize the extraction process. Based on importance, three parameters were selected, namely, initial homogenization temperature, homogenization time and solid (g) to solvent (ml) ratio. Maximum inhibition to fungal growth was found when the extraction was carried out as follows; using initial homogenization temperature of 4°C, homogenization time of 5 minutes and a solid (g) to solvent (ml) ratio of 3.5:1. The peptide extract displayed different degree of antifungal effect towards four selected fungi, Aspergillus niger, Microsporum canis, Candida albicans and Blastomyces dermatitidsis.
format Conference or Workshop Item
author Faruck, Mohammad Omer
Yusof, Faridah
Chowdhury , Silvia
author_facet Faruck, Mohammad Omer
Yusof, Faridah
Chowdhury , Silvia
author_sort Faruck, Mohammad Omer
title Effect of some parameters on the extraction process of antifungal peptides from Supermeal worm, Zophobas morio (Fabricius)
title_short Effect of some parameters on the extraction process of antifungal peptides from Supermeal worm, Zophobas morio (Fabricius)
title_full Effect of some parameters on the extraction process of antifungal peptides from Supermeal worm, Zophobas morio (Fabricius)
title_fullStr Effect of some parameters on the extraction process of antifungal peptides from Supermeal worm, Zophobas morio (Fabricius)
title_full_unstemmed Effect of some parameters on the extraction process of antifungal peptides from Supermeal worm, Zophobas morio (Fabricius)
title_sort effect of some parameters on the extraction process of antifungal peptides from supermeal worm, zophobas morio (fabricius)
publisher Kulliyah of Engineering, International Islamic University Malaysia
publishDate 2016
url http://irep.iium.edu.my/51733/1/51733.pdf
http://irep.iium.edu.my/51733/
http://www.iium.edu.my/icbioe/2016/
_version_ 1643614023801896960
score 13.211869

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