Influence of lipids on the hydrophobic barrier within the pore of the TWIK-1 K2P channel
Several recent ion channel structures have revealed large side portals, or ‘fenestrations’ at the interface between their transmembrane helices that potentially expose the ion conduction pathway to the lipid core of the bilayer. In a recent study we demonstrated that functional activity of the TWIK-...
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Main Authors: | Aryal, Prafulla, Abd. Wahab, Mohd. Firdaus, Bucci, Giovanna, Sansom, Mark S.P., Tucker, Stephen J. |
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Format: | Article |
Language: | English |
Published: |
Taylor and Francis Group, LLC
2015
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Subjects: | |
Online Access: | http://irep.iium.edu.my/50082/1/50082.pdf http://irep.iium.edu.my/50082/ http://www.tandfonline.com/doi/full/10.4161/19336950.2014.981987 |
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