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The effect of Nigella sativa extract on mouse oocyte activation

Female infertility cases have been increased worldwide by several factors including lifestyle. Nigella sativa is a well-known medicinal plant which has been used globally for prevention and cure of many diseases. Nigella sativa with its active components were thought to be a solution for the inferti...

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Main Authors: Abdul Rahman, Suzanah, Enseri, Mohd Qairul Amir, Abdul Samat, Nadia Hanis
Format: Conference or Workshop Item
Language:English
Published: 2014
Subjects:
RM Therapeutics. Pharmacology
Online Access:http://irep.iium.edu.my/49398/1/49398.pdf
http://irep.iium.edu.my/49398/
http://www.iium.edu.my/ihci/
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spelling my.iium.irep.493982016-05-12T01:34:19Z http://irep.iium.edu.my/49398/ The effect of Nigella sativa extract on mouse oocyte activation Abdul Rahman, Suzanah Enseri, Mohd Qairul Amir Abdul Samat, Nadia Hanis RM Therapeutics. Pharmacology Female infertility cases have been increased worldwide by several factors including lifestyle. Nigella sativa is a well-known medicinal plant which has been used globally for prevention and cure of many diseases. Nigella sativa with its active components were thought to be a solution for the infertility problem. Thus in this experiment, the effects of Nigella sativa on the number of oocytes and number of fertilized oocytes were investigated. This was carried out by treating 20 Balb/c female mice divided equally into groups of four; i) control group (no treatment given), ii) treated with 25mg/kg per body weight of Nigella sativa, iii) treated with 50mg/kg per body weight of Nigella sativa, and iv) treated with 75mg/kg per body weight of Nigella sativa. The treatments were given daily for five days (estrous cycle) via intraperitoneal (i.p.) injection. Then, they were sacrificed and oocytes were obtained, followed by in vitro fertilization process. Total number of oocytes obtained was calculated and total number of fertilized oocytes was recorded. This study discovered that Nigella sativa supplementation did not indicate any significant difference (p>0.05) in the effect of different doses of Nigella sativa with total number of oocytes produced as well as the total number of fertilized oocytes. It was concluded that Nigella sativa did not increase the number of oocytes and the number of fertilized oocytes produced in mice. 2014 Conference or Workshop Item REM application/pdf en http://irep.iium.edu.my/49398/1/49398.pdf Abdul Rahman, Suzanah and Enseri, Mohd Qairul Amir and Abdul Samat, Nadia Hanis (2014) The effect of Nigella sativa extract on mouse oocyte activation. In: International Health Conference IIUM (IHCI 2014), 3rd-4th Dec. 2014, Kuantan, Pahang. (Unpublished) http://www.iium.edu.my/ihci/
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic RM Therapeutics. Pharmacology
spellingShingle RM Therapeutics. Pharmacology
Abdul Rahman, Suzanah
Enseri, Mohd Qairul Amir
Abdul Samat, Nadia Hanis
The effect of Nigella sativa extract on mouse oocyte activation
description Female infertility cases have been increased worldwide by several factors including lifestyle. Nigella sativa is a well-known medicinal plant which has been used globally for prevention and cure of many diseases. Nigella sativa with its active components were thought to be a solution for the infertility problem. Thus in this experiment, the effects of Nigella sativa on the number of oocytes and number of fertilized oocytes were investigated. This was carried out by treating 20 Balb/c female mice divided equally into groups of four; i) control group (no treatment given), ii) treated with 25mg/kg per body weight of Nigella sativa, iii) treated with 50mg/kg per body weight of Nigella sativa, and iv) treated with 75mg/kg per body weight of Nigella sativa. The treatments were given daily for five days (estrous cycle) via intraperitoneal (i.p.) injection. Then, they were sacrificed and oocytes were obtained, followed by in vitro fertilization process. Total number of oocytes obtained was calculated and total number of fertilized oocytes was recorded. This study discovered that Nigella sativa supplementation did not indicate any significant difference (p>0.05) in the effect of different doses of Nigella sativa with total number of oocytes produced as well as the total number of fertilized oocytes. It was concluded that Nigella sativa did not increase the number of oocytes and the number of fertilized oocytes produced in mice.
format Conference or Workshop Item
author Abdul Rahman, Suzanah
Enseri, Mohd Qairul Amir
Abdul Samat, Nadia Hanis
author_facet Abdul Rahman, Suzanah
Enseri, Mohd Qairul Amir
Abdul Samat, Nadia Hanis
author_sort Abdul Rahman, Suzanah
title The effect of Nigella sativa extract on mouse oocyte activation
title_short The effect of Nigella sativa extract on mouse oocyte activation
title_full The effect of Nigella sativa extract on mouse oocyte activation
title_fullStr The effect of Nigella sativa extract on mouse oocyte activation
title_full_unstemmed The effect of Nigella sativa extract on mouse oocyte activation
title_sort effect of nigella sativa extract on mouse oocyte activation
publishDate 2014
url http://irep.iium.edu.my/49398/1/49398.pdf
http://irep.iium.edu.my/49398/
http://www.iium.edu.my/ihci/
_version_ 1643613529588105216
score 13.211869

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