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Antimicrobial activities of stembark and wood extracts from Nuclea subdita against pathogenic microorganisms

The aim of the study was to investigate the antimicrobial activity of Nuclea subdita (Korth) Steud against six pathogenic microorganisms. Methodology and results: Young and maturedtrees ao N. subdita were cut and separated into bark and wood parts, respectively, prior to extraction process. Phytoche...

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Main Authors: Jamaluddin, Fatin Ruzanna, Lee, Seng Hua, Ashaari, Zaidon, Wahab, Razak, Mohd Daud, Jamaluddin
Format: Article
Language:English
Published: Malaysian Society for Microbiology 2015
Subjects:
Q Science (General)
Online Access:http://irep.iium.edu.my/48495/1/Paper_Antimicrobial_Nauclea_subdita_6-Vol_11-4-MJM_720-15_%28FINAL%29_Dec_2015.pdf
http://irep.iium.edu.my/48495/
http://web.usm.my/mjm
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spelling my.iium.irep.484952016-12-19T07:55:20Z http://irep.iium.edu.my/48495/ Antimicrobial activities of stembark and wood extracts from Nuclea subdita against pathogenic microorganisms Jamaluddin, Fatin Ruzanna Lee, Seng Hua Ashaari, Zaidon Wahab, Razak Mohd Daud, Jamaluddin Q Science (General) The aim of the study was to investigate the antimicrobial activity of Nuclea subdita (Korth) Steud against six pathogenic microorganisms. Methodology and results: Young and maturedtrees ao N. subdita were cut and separated into bark and wood parts, respectively, prior to extraction process. Phytochemical screening tests, antimicrobial activity, minimal inhibitory concentration (MIC) and minimal bacterial concentration (MBC) values were determined. Preliminary screening for phytochemical components showed that both young and matured tree had similar constituents. Extracts from matured tree showed more potency in terms of the zones of inhibition sizes than the young tree. Extract of N. subdita was more potent to both marine bacteria, Vibrio parahaemoliticus and V. alginolyticus, while Candida albican and Aspergillus niger were resistant to it. The sensitivity test showed that 500 ug/mL is the optimum concentration for extract of bottom sapwood of mature tree to act as bactericidal. Conclusion, significance and impact study: The results from this study suggest that N. subdita bark and wood extracts may serve as potential source of antimicrobial agents for future development in medicine applications. Malaysian Society for Microbiology 2015 Article REM application/pdf en http://irep.iium.edu.my/48495/1/Paper_Antimicrobial_Nauclea_subdita_6-Vol_11-4-MJM_720-15_%28FINAL%29_Dec_2015.pdf Jamaluddin, Fatin Ruzanna and Lee, Seng Hua and Ashaari, Zaidon and Wahab, Razak and Mohd Daud, Jamaluddin (2015) Antimicrobial activities of stembark and wood extracts from Nuclea subdita against pathogenic microorganisms. Malaysian Journal of Microbiolog, 11 (4). pp. 365-372. ISSN 1823-8262 http://web.usm.my/mjm
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic Q Science (General)
spellingShingle Q Science (General)
Jamaluddin, Fatin Ruzanna
Lee, Seng Hua
Ashaari, Zaidon
Wahab, Razak
Mohd Daud, Jamaluddin
Antimicrobial activities of stembark and wood extracts from Nuclea subdita against pathogenic microorganisms
description The aim of the study was to investigate the antimicrobial activity of Nuclea subdita (Korth) Steud against six pathogenic microorganisms. Methodology and results: Young and maturedtrees ao N. subdita were cut and separated into bark and wood parts, respectively, prior to extraction process. Phytochemical screening tests, antimicrobial activity, minimal inhibitory concentration (MIC) and minimal bacterial concentration (MBC) values were determined. Preliminary screening for phytochemical components showed that both young and matured tree had similar constituents. Extracts from matured tree showed more potency in terms of the zones of inhibition sizes than the young tree. Extract of N. subdita was more potent to both marine bacteria, Vibrio parahaemoliticus and V. alginolyticus, while Candida albican and Aspergillus niger were resistant to it. The sensitivity test showed that 500 ug/mL is the optimum concentration for extract of bottom sapwood of mature tree to act as bactericidal. Conclusion, significance and impact study: The results from this study suggest that N. subdita bark and wood extracts may serve as potential source of antimicrobial agents for future development in medicine applications.
format Article
author Jamaluddin, Fatin Ruzanna
Lee, Seng Hua
Ashaari, Zaidon
Wahab, Razak
Mohd Daud, Jamaluddin
author_facet Jamaluddin, Fatin Ruzanna
Lee, Seng Hua
Ashaari, Zaidon
Wahab, Razak
Mohd Daud, Jamaluddin
author_sort Jamaluddin, Fatin Ruzanna
title Antimicrobial activities of stembark and wood extracts from Nuclea subdita against pathogenic microorganisms
title_short Antimicrobial activities of stembark and wood extracts from Nuclea subdita against pathogenic microorganisms
title_full Antimicrobial activities of stembark and wood extracts from Nuclea subdita against pathogenic microorganisms
title_fullStr Antimicrobial activities of stembark and wood extracts from Nuclea subdita against pathogenic microorganisms
title_full_unstemmed Antimicrobial activities of stembark and wood extracts from Nuclea subdita against pathogenic microorganisms
title_sort antimicrobial activities of stembark and wood extracts from nuclea subdita against pathogenic microorganisms
publisher Malaysian Society for Microbiology
publishDate 2015
url http://irep.iium.edu.my/48495/1/Paper_Antimicrobial_Nauclea_subdita_6-Vol_11-4-MJM_720-15_%28FINAL%29_Dec_2015.pdf
http://irep.iium.edu.my/48495/
http://web.usm.my/mjm
_version_ 1643613373951115264
score 13.211869

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