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Antioxidant and antibacterial activities of ruta angustifolia extract

Ruta angustifolia was used in this study in order to evaluate the antimicrobial activity and antioxidant properties and its correlation with the polyphenolic content. Two Gram-positive bacteria (Staphylococcus aureus ATCC 25923, Bacillus cereus ATCC 11778) and two Gram–negative bacteria (Pseudomonas...

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Main Authors: Shuib, Nur Azra, Sulaiman, Fatimatul Akmal, Razak , Izzatie, Darnis, Deny Susanti
Format: Article
Language:English
Published: Universiti Teknologi Malaysia 2015
Online Access:http://irep.iium.edu.my/47395/1/6747-18528-1-SM.pdf
http://irep.iium.edu.my/47395/
http://www.jurnalteknologi.utm.my/index.php/jurnalteknologi/article/view/6747
http://dx.doi.org/10.11113/jt.v77.6747
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spelling my.iium.irep.473952018-05-22T03:23:29Z http://irep.iium.edu.my/47395/ Antioxidant and antibacterial activities of ruta angustifolia extract Shuib, Nur Azra Sulaiman, Fatimatul Akmal Razak , Izzatie Darnis, Deny Susanti Ruta angustifolia was used in this study in order to evaluate the antimicrobial activity and antioxidant properties and its correlation with the polyphenolic content. Two Gram-positive bacteria (Staphylococcus aureus ATCC 25923, Bacillus cereus ATCC 11778) and two Gram–negative bacteria (Pseudomonas aeruginosa ATCC 27853, Escherichia coli ATCC 8739) were used to determine the antibacterial activity. Aqueous maceration extract was used for antioxidant activities and methanolic maceration extract was used for antibacterial activity. The antioxidant properties and activities were evaluated by using total phenolic content (TPC), total flavonoid content (TFC), DPPH free radical scavenging activity and beta-carotene bleaching method. Whereas, the antibacterial activity was examined using disc diffusion method against selected microorganism at concentration 1.0 mg/disc. The results showed the phenolic content of R. angustifolia extract was 18.89 g GAE/100 g extract while the flavonoid content was 14.170 g QE/100 g extract. R. angustifolia exhibited good radical scavenging with IC50 value of 2.04 mg/ml. The result for disc diffusion method showed no inhibition zone against all the strains of bacteria at 1.0 mg/disc concentration of the extract. Based on the results, it can be concluded that the R. angustifolia aqueous extract has the antioxidant properties and there is correlation between polyphenolic content of the extract with its antioxidant activity. However, R. angustifolia methanolic extract did not show any antibacterial activity. Universiti Teknologi Malaysia 2015 Article REM application/pdf en http://irep.iium.edu.my/47395/1/6747-18528-1-SM.pdf Shuib, Nur Azra and Sulaiman, Fatimatul Akmal and Razak , Izzatie and Darnis, Deny Susanti (2015) Antioxidant and antibacterial activities of ruta angustifolia extract. Jurnal Teknologi, 77 (25). pp. 101-105. ISSN 0127–9696 http://www.jurnalteknologi.utm.my/index.php/jurnalteknologi/article/view/6747 http://dx.doi.org/10.11113/jt.v77.6747
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
description Ruta angustifolia was used in this study in order to evaluate the antimicrobial activity and antioxidant properties and its correlation with the polyphenolic content. Two Gram-positive bacteria (Staphylococcus aureus ATCC 25923, Bacillus cereus ATCC 11778) and two Gram–negative bacteria (Pseudomonas aeruginosa ATCC 27853, Escherichia coli ATCC 8739) were used to determine the antibacterial activity. Aqueous maceration extract was used for antioxidant activities and methanolic maceration extract was used for antibacterial activity. The antioxidant properties and activities were evaluated by using total phenolic content (TPC), total flavonoid content (TFC), DPPH free radical scavenging activity and beta-carotene bleaching method. Whereas, the antibacterial activity was examined using disc diffusion method against selected microorganism at concentration 1.0 mg/disc. The results showed the phenolic content of R. angustifolia extract was 18.89 g GAE/100 g extract while the flavonoid content was 14.170 g QE/100 g extract. R. angustifolia exhibited good radical scavenging with IC50 value of 2.04 mg/ml. The result for disc diffusion method showed no inhibition zone against all the strains of bacteria at 1.0 mg/disc concentration of the extract. Based on the results, it can be concluded that the R. angustifolia aqueous extract has the antioxidant properties and there is correlation between polyphenolic content of the extract with its antioxidant activity. However, R. angustifolia methanolic extract did not show any antibacterial activity.
format Article
author Shuib, Nur Azra
Sulaiman, Fatimatul Akmal
Razak , Izzatie
Darnis, Deny Susanti
spellingShingle Shuib, Nur Azra
Sulaiman, Fatimatul Akmal
Razak , Izzatie
Darnis, Deny Susanti
Antioxidant and antibacterial activities of ruta angustifolia extract
author_facet Shuib, Nur Azra
Sulaiman, Fatimatul Akmal
Razak , Izzatie
Darnis, Deny Susanti
author_sort Shuib, Nur Azra
title Antioxidant and antibacterial activities of ruta angustifolia extract
title_short Antioxidant and antibacterial activities of ruta angustifolia extract
title_full Antioxidant and antibacterial activities of ruta angustifolia extract
title_fullStr Antioxidant and antibacterial activities of ruta angustifolia extract
title_full_unstemmed Antioxidant and antibacterial activities of ruta angustifolia extract
title_sort antioxidant and antibacterial activities of ruta angustifolia extract
publisher Universiti Teknologi Malaysia
publishDate 2015
url http://irep.iium.edu.my/47395/1/6747-18528-1-SM.pdf
http://irep.iium.edu.my/47395/
http://www.jurnalteknologi.utm.my/index.php/jurnalteknologi/article/view/6747
http://dx.doi.org/10.11113/jt.v77.6747
_version_ 1643613184302514176
score 13.211869

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