Potential novel inhibitors of trypanosomatid phosphoglycerate mutases through ligand-based and structure-based in silico approaches

Background & Hypothesis: The parasitic protozoa from the order Trypanosomatida relies exclusively on glycolysis for its survival in the mammalian hosts. As a corollary, the enzymes in this pathway have been recognised as chemotherapeutic targets. Phosphoglycerate mutase (iPGAM), which is the se...

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Bibliographic Details
Main Authors: Ahmad Fuad, Fazia Adyani, Walkinshaw, Malcolm D., Fothergill-Gilmore, Linda A., Houston, Dr.
Format: Conference or Workshop Item
Language:English
Published: Academy of Medicine, Singapore 2015
Subjects:
Online Access:http://irep.iium.edu.my/45423/1/45423.pdf
http://irep.iium.edu.my/45423/
http://www.annals.edu.sg/past.html
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