Cover Image

Cost-effectiveness of antihypertensive treatment in Malaysia

Hypertension is a prevalent chronic disease, which is strongly related to the development of cerebrovascular and cardiovascular diseases. The prevalence of hypertension in Malaysia in subjects aged 15 years and above was estimated to be 27.8%. Cost-effectiveness analysis (CEA) compares treatment opt...

Full description

Saved in:
Bibliographic Details
Main Authors: Al-Efan, Qais Muhammad Ahmad, M. Ibrahim, M. Izham, Abdul Razak, Tariq, Ayob, Azizi
Format: Article
Language:English
Published: Penerbit USM 2009
Subjects:
RC Internal medicine
Online Access:http://irep.iium.edu.my/454/1/cost-effectiveness_of_antihypertensive_treatment_in_Malaysia.pdf
http://irep.iium.edu.my/454/
http://web.usm.my/mjps/vol_7-2.html
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.iium.irep.454
record_format dspace
spelling my.iium.irep.4542011-06-17T08:08:36Z http://irep.iium.edu.my/454/ Cost-effectiveness of antihypertensive treatment in Malaysia Al-Efan, Qais Muhammad Ahmad M. Ibrahim, M. Izham Abdul Razak, Tariq Ayob, Azizi RC Internal medicine Hypertension is a prevalent chronic disease, which is strongly related to the development of cerebrovascular and cardiovascular diseases. The prevalence of hypertension in Malaysia in subjects aged 15 years and above was estimated to be 27.8%. Cost-effectiveness analysis (CEA) compares treatment options with different effectiveness and safety profiles. The utilisation of antihypertensive drugs has raised some concerns about the balance between its costs and benefits. This study was conducted to describe the healthcare costs for hypertensive subjects and to examine the cost-effectiveness of different classes of antihypertensive drugs used in Malaysia. Retrospective and prospective data analysis of a cohort of uncomplicated hypertensive patients was conducted to determine ambulatory health care costs among hypertensive patients groups. The total direct and indirect costs of controlled and uncontrolled blood pressure (BP) were described. The health care costs ($) / clinical outcome (AC/E ratio) was calculated. Mean total direct costs per patient per month was higher in uncontrolled blood pressure groups compared to the controlled blood pressure groups. The cost-effectiveness relationship was more favourable for diuretics (1.9), angiotensin converting enzyme inhibitors (ACEIs) (2.0), prazosin (2.4) and beta blockers (2.5), more than the diuretics and beta blockers combination theraphy (3.0), calcium channel blockers (CCBs) (3.4) and other combinations (6.1). Antihypertensive drugs used to treat hypertensive patients were different in their cost-effectiveness ratios. Such results will allow health care professionals and/or decision makers to make better decisions on how to select treatment options for hypertensive patients in Malaysia and how to distribute and allocate scarce health care resources. Pharmacoeconomic evaluations can help in making difficult choices rationally and allocate scarce resources efficiently. Penerbit USM 2009 Article REM application/pdf en http://irep.iium.edu.my/454/1/cost-effectiveness_of_antihypertensive_treatment_in_Malaysia.pdf Al-Efan, Qais Muhammad Ahmad and M. Ibrahim, M. Izham and Abdul Razak, Tariq and Ayob, Azizi (2009) Cost-effectiveness of antihypertensive treatment in Malaysia. Malaysian Journal of Pharmaceutical Sciences, 7 (2). pp. 137-152. ISSN 2180-429X http://web.usm.my/mjps/vol_7-2.html
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic RC Internal medicine
spellingShingle RC Internal medicine
Al-Efan, Qais Muhammad Ahmad
M. Ibrahim, M. Izham
Abdul Razak, Tariq
Ayob, Azizi
Cost-effectiveness of antihypertensive treatment in Malaysia
description Hypertension is a prevalent chronic disease, which is strongly related to the development of cerebrovascular and cardiovascular diseases. The prevalence of hypertension in Malaysia in subjects aged 15 years and above was estimated to be 27.8%. Cost-effectiveness analysis (CEA) compares treatment options with different effectiveness and safety profiles. The utilisation of antihypertensive drugs has raised some concerns about the balance between its costs and benefits. This study was conducted to describe the healthcare costs for hypertensive subjects and to examine the cost-effectiveness of different classes of antihypertensive drugs used in Malaysia. Retrospective and prospective data analysis of a cohort of uncomplicated hypertensive patients was conducted to determine ambulatory health care costs among hypertensive patients groups. The total direct and indirect costs of controlled and uncontrolled blood pressure (BP) were described. The health care costs ($) / clinical outcome (AC/E ratio) was calculated. Mean total direct costs per patient per month was higher in uncontrolled blood pressure groups compared to the controlled blood pressure groups. The cost-effectiveness relationship was more favourable for diuretics (1.9), angiotensin converting enzyme inhibitors (ACEIs) (2.0), prazosin (2.4) and beta blockers (2.5), more than the diuretics and beta blockers combination theraphy (3.0), calcium channel blockers (CCBs) (3.4) and other combinations (6.1). Antihypertensive drugs used to treat hypertensive patients were different in their cost-effectiveness ratios. Such results will allow health care professionals and/or decision makers to make better decisions on how to select treatment options for hypertensive patients in Malaysia and how to distribute and allocate scarce health care resources. Pharmacoeconomic evaluations can help in making difficult choices rationally and allocate scarce resources efficiently.
format Article
author Al-Efan, Qais Muhammad Ahmad
M. Ibrahim, M. Izham
Abdul Razak, Tariq
Ayob, Azizi
author_facet Al-Efan, Qais Muhammad Ahmad
M. Ibrahim, M. Izham
Abdul Razak, Tariq
Ayob, Azizi
author_sort Al-Efan, Qais Muhammad Ahmad
title Cost-effectiveness of antihypertensive treatment in Malaysia
title_short Cost-effectiveness of antihypertensive treatment in Malaysia
title_full Cost-effectiveness of antihypertensive treatment in Malaysia
title_fullStr Cost-effectiveness of antihypertensive treatment in Malaysia
title_full_unstemmed Cost-effectiveness of antihypertensive treatment in Malaysia
title_sort cost-effectiveness of antihypertensive treatment in malaysia
publisher Penerbit USM
publishDate 2009
url http://irep.iium.edu.my/454/1/cost-effectiveness_of_antihypertensive_treatment_in_Malaysia.pdf
http://irep.iium.edu.my/454/
http://web.usm.my/mjps/vol_7-2.html
_version_ 1643604614676742144
score 13.211869

Similar Items