Cover Image

The effect of renal stones on serum adenosine aminohydrolase and AMP-aminohydrolase in Malaysia

Objective To verify possible associations between adenosine aminohydrolase (ADA) and AMP-aminohydrolase (AMPDA) to E3 SUMO-protein ligase NSE2 (NSMCE2) in patients with renal stones. And to isolate, purify and characterize ADA in patients with renal stones and healthy group. Methods A total...

Full description

Saved in:
Bibliographic Details
Main Authors: Yusof, Faridah, Mehde, Atheer Awad, Ghazali, Hamid, Abd Rahman, Azlina
Format: Article
Language:English
English
Published: Elsevier 2015
Subjects:
R Medicine (General)
Online Access:http://irep.iium.edu.my/44462/1/P_62.pdf
http://irep.iium.edu.my/44462/4/44462_The%20effect%20of%20renal%20stones%20on%20serum%20adenosine%20aminohydrolase%20and%20AMP-aminohydrolase%20in%20Malaysia_SCOPUS.pdf
http://irep.iium.edu.my/44462/
http://www.sciencedirect.com/science/article/pii/S2221169115000738
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.iium.irep.44462
record_format dspace
spelling my.iium.irep.444622017-11-17T07:44:03Z http://irep.iium.edu.my/44462/ The effect of renal stones on serum adenosine aminohydrolase and AMP-aminohydrolase in Malaysia Yusof, Faridah Mehde, Atheer Awad Ghazali, Hamid Abd Rahman, Azlina R Medicine (General) Objective To verify possible associations between adenosine aminohydrolase (ADA) and AMP-aminohydrolase (AMPDA) to E3 SUMO-protein ligase NSE2 (NSMCE2) in patients with renal stones. And to isolate, purify and characterize ADA in patients with renal stones and healthy group. Methods A total of 60 renal stones patients and 50 control were enrolled in a case–control study. The blood urea, creatinine, uric acid, protein, albumin, ADA and AMPDA were measured by colorimetric tests. The serum NSMCE2 was measured by ELISA. Results Serum ADA, AMPDA and specific activity of enzymes showed significant decrease (P < 0.05) in patients with renal stones compared to control group, mean levels of sera NSMCE2 and uric acid had a significant increase (P < 0.01 and P < 0.05, respectively) in patients compared to control group. Conclusions The present study suggests that ADA, AMP deaminase and NSMCE2 can be used as a indicator to monitor the DNA damage and inflammation disorders in the patients with kidney stones. Elsevier 2015-06 Article REM application/pdf en http://irep.iium.edu.my/44462/1/P_62.pdf application/pdf en http://irep.iium.edu.my/44462/4/44462_The%20effect%20of%20renal%20stones%20on%20serum%20adenosine%20aminohydrolase%20and%20AMP-aminohydrolase%20in%20Malaysia_SCOPUS.pdf Yusof, Faridah and Mehde, Atheer Awad and Ghazali, Hamid and Abd Rahman, Azlina (2015) The effect of renal stones on serum adenosine aminohydrolase and AMP-aminohydrolase in Malaysia. Asian Pacific Journal of Tropical Biomedicine, 5 (6). pp. 478-484. ISSN 2221 1691 http://www.sciencedirect.com/science/article/pii/S2221169115000738 10.1016/j.apjtb.2015.04.003
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
English
topic R Medicine (General)
spellingShingle R Medicine (General)
Yusof, Faridah
Mehde, Atheer Awad
Ghazali, Hamid
Abd Rahman, Azlina
The effect of renal stones on serum adenosine aminohydrolase and AMP-aminohydrolase in Malaysia
description Objective To verify possible associations between adenosine aminohydrolase (ADA) and AMP-aminohydrolase (AMPDA) to E3 SUMO-protein ligase NSE2 (NSMCE2) in patients with renal stones. And to isolate, purify and characterize ADA in patients with renal stones and healthy group. Methods A total of 60 renal stones patients and 50 control were enrolled in a case–control study. The blood urea, creatinine, uric acid, protein, albumin, ADA and AMPDA were measured by colorimetric tests. The serum NSMCE2 was measured by ELISA. Results Serum ADA, AMPDA and specific activity of enzymes showed significant decrease (P < 0.05) in patients with renal stones compared to control group, mean levels of sera NSMCE2 and uric acid had a significant increase (P < 0.01 and P < 0.05, respectively) in patients compared to control group. Conclusions The present study suggests that ADA, AMP deaminase and NSMCE2 can be used as a indicator to monitor the DNA damage and inflammation disorders in the patients with kidney stones.
format Article
author Yusof, Faridah
Mehde, Atheer Awad
Ghazali, Hamid
Abd Rahman, Azlina
author_facet Yusof, Faridah
Mehde, Atheer Awad
Ghazali, Hamid
Abd Rahman, Azlina
author_sort Yusof, Faridah
title The effect of renal stones on serum adenosine aminohydrolase and AMP-aminohydrolase in Malaysia
title_short The effect of renal stones on serum adenosine aminohydrolase and AMP-aminohydrolase in Malaysia
title_full The effect of renal stones on serum adenosine aminohydrolase and AMP-aminohydrolase in Malaysia
title_fullStr The effect of renal stones on serum adenosine aminohydrolase and AMP-aminohydrolase in Malaysia
title_full_unstemmed The effect of renal stones on serum adenosine aminohydrolase and AMP-aminohydrolase in Malaysia
title_sort effect of renal stones on serum adenosine aminohydrolase and amp-aminohydrolase in malaysia
publisher Elsevier
publishDate 2015
url http://irep.iium.edu.my/44462/1/P_62.pdf
http://irep.iium.edu.my/44462/4/44462_The%20effect%20of%20renal%20stones%20on%20serum%20adenosine%20aminohydrolase%20and%20AMP-aminohydrolase%20in%20Malaysia_SCOPUS.pdf
http://irep.iium.edu.my/44462/
http://www.sciencedirect.com/science/article/pii/S2221169115000738
_version_ 1643612578719465472
score 13.222552

Similar Items