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Effects of oil palm (elais guineensis) fruit extracts on glucose uptake activity of muscle, adipose and liver cells

The effect of oil palm (Elaeis guineensis) fruit aqueous extract (OPF) on glucose uptake activity of three different cell lines was investigated. The cell lines were incubated with different concentrations of OPF to evaluate the stimulatory effect of OPF towards glucose uptake activity of L6 myotube...

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Main Authors: Sharif, Faez, Hamid, Muhajir, Ismail, Amin, Adam, Zainah
Format: Article
Language:English
Published: Universiti Putra Malaysia Press 2014
Subjects:
QH301 Biology
Online Access:http://irep.iium.edu.my/42573/1/Contents_AJSTD_31%282%29_2014.pdf
http://irep.iium.edu.my/42573/
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spelling my.iium.irep.425732016-02-02T04:42:00Z http://irep.iium.edu.my/42573/ Effects of oil palm (elais guineensis) fruit extracts on glucose uptake activity of muscle, adipose and liver cells Sharif, Faez Hamid, Muhajir Ismail, Amin Adam, Zainah QH301 Biology The effect of oil palm (Elaeis guineensis) fruit aqueous extract (OPF) on glucose uptake activity of three different cell lines was investigated. The cell lines were incubated with different concentrations of OPF to evaluate the stimulatory effect of OPF towards glucose uptake activity of L6 myotubes, 3T3F442A adipocytes and Chang liver cell line. The glucose uptake activities of all tested cells were enhanced in the presence of OPF extract (basal condition). Nevertheless in combination of OPF extract and 100 nM insulin, the glucose uptake activity was only significantly enhanced in L6 myotubes and 3T3F442A adipocytes cell lines. The extracts enhanced the glucose uptake into cells through either insulin-mimetic or insulin-sensitizing property or combination of these two properties. It can be suggested that the OPF extract exerts its antihyperglycemic action partly by mediated glucose uptake into the glucose-responsive disposal cells, muscle, adipose and liver. Universiti Putra Malaysia Press 2014 Article REM application/pdf en http://irep.iium.edu.my/42573/1/Contents_AJSTD_31%282%29_2014.pdf Sharif, Faez and Hamid, Muhajir and Ismail, Amin and Adam, Zainah (2014) Effects of oil palm (elais guineensis) fruit extracts on glucose uptake activity of muscle, adipose and liver cells. ASEAN Journal on Science and Technology for Development, 31 (2). pp. 83-89. ISSN 0217-5460
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic QH301 Biology
spellingShingle QH301 Biology
Sharif, Faez
Hamid, Muhajir
Ismail, Amin
Adam, Zainah
Effects of oil palm (elais guineensis) fruit extracts on glucose uptake activity of muscle, adipose and liver cells
description The effect of oil palm (Elaeis guineensis) fruit aqueous extract (OPF) on glucose uptake activity of three different cell lines was investigated. The cell lines were incubated with different concentrations of OPF to evaluate the stimulatory effect of OPF towards glucose uptake activity of L6 myotubes, 3T3F442A adipocytes and Chang liver cell line. The glucose uptake activities of all tested cells were enhanced in the presence of OPF extract (basal condition). Nevertheless in combination of OPF extract and 100 nM insulin, the glucose uptake activity was only significantly enhanced in L6 myotubes and 3T3F442A adipocytes cell lines. The extracts enhanced the glucose uptake into cells through either insulin-mimetic or insulin-sensitizing property or combination of these two properties. It can be suggested that the OPF extract exerts its antihyperglycemic action partly by mediated glucose uptake into the glucose-responsive disposal cells, muscle, adipose and liver.
format Article
author Sharif, Faez
Hamid, Muhajir
Ismail, Amin
Adam, Zainah
author_facet Sharif, Faez
Hamid, Muhajir
Ismail, Amin
Adam, Zainah
author_sort Sharif, Faez
title Effects of oil palm (elais guineensis) fruit extracts on glucose uptake activity of muscle, adipose and liver cells
title_short Effects of oil palm (elais guineensis) fruit extracts on glucose uptake activity of muscle, adipose and liver cells
title_full Effects of oil palm (elais guineensis) fruit extracts on glucose uptake activity of muscle, adipose and liver cells
title_fullStr Effects of oil palm (elais guineensis) fruit extracts on glucose uptake activity of muscle, adipose and liver cells
title_full_unstemmed Effects of oil palm (elais guineensis) fruit extracts on glucose uptake activity of muscle, adipose and liver cells
title_sort effects of oil palm (elais guineensis) fruit extracts on glucose uptake activity of muscle, adipose and liver cells
publisher Universiti Putra Malaysia Press
publishDate 2014
url http://irep.iium.edu.my/42573/1/Contents_AJSTD_31%282%29_2014.pdf
http://irep.iium.edu.my/42573/
_version_ 1643612212462354432
score 13.211869

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