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Particle formation and micronization using non-conventional techniques- review

Due to growing concerns regarding health, safety and the environment, non-conventional methods for particle formation and micronization that are either solvent-less or use environmentally acceptable solvents such as carbon dioxide have come into favor. Supercritical CO2 (sc CO2) (T > 31.1 '...

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Main Authors: Karim, Fahim Tamzeedul, Sarker, Md. Zaidul Islam, Abu Bakar, Mohd Rushdi, U.M., Salim, Awang, Mohamed, Ferdosh, Sahena, Khan Chowdhury, Ahmed Jalal, Sharif, K. M., Hossain, Md Sohrab
Format: Article
Language:English
English
Published: Elsevier B.V 2014
Subjects:
Q Science (General)
T Technology (General)
Online Access:http://irep.iium.edu.my/38952/1/JSF-paper-2014.pdf
http://irep.iium.edu.my/38952/4/38952_Particle%20formation%20and%20micronization.SCOPUS.pdf
http://irep.iium.edu.my/38952/
http://www.journals.elsevier.com/chemical-engineering-and-processing-process-intensification/
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spelling my.iium.irep.389522019-10-09T08:20:14Z http://irep.iium.edu.my/38952/ Particle formation and micronization using non-conventional techniques- review Karim, Fahim Tamzeedul Sarker, Md. Zaidul Islam Abu Bakar, Mohd Rushdi U.M., Salim Awang, Mohamed Ferdosh, Sahena Khan Chowdhury, Ahmed Jalal Sharif, K. M. Hossain, Md Sohrab Q Science (General) T Technology (General) Due to growing concerns regarding health, safety and the environment, non-conventional methods for particle formation and micronization that are either solvent-less or use environmentally acceptable solvents such as carbon dioxide have come into favor. Supercritical CO2 (sc CO2) (T > 31.1 'C, P > 7.3 MPa) has been used in food and pharmaceutical industries to minimize the use of organic solvents, produce new food products, produce environmentally superior food products and to process and micronize (0.1–5mm) pharmaceuticals. Control of particle size increases the dissolution rate of drugs into the body. Techniques that use sc CO2 eliminate inherent drawbacks of conventional methods such as thermal or mechanical degradation of the product, poor control of the particle size and morphology, lack of brittleness of some polymers and low encapsulation efficiency. Severaltechniques have been reported for the particle formation and micronization using supercritical fluids that have been successfully scaled up for commercial use. Supercritical CO2 has also been used to develop applications for medicines, essential oils, vitamins, food grade polymers, catalysts and pigments. This review highlights the process mechanism of supercritical fluid based techniques as well as some applications on particle formation and micronization. Elsevier B.V 2014-10-22 Article PeerReviewed application/pdf en http://irep.iium.edu.my/38952/1/JSF-paper-2014.pdf application/pdf en http://irep.iium.edu.my/38952/4/38952_Particle%20formation%20and%20micronization.SCOPUS.pdf Karim, Fahim Tamzeedul and Sarker, Md. Zaidul Islam and Abu Bakar, Mohd Rushdi and U.M., Salim and Awang, Mohamed and Ferdosh, Sahena and Khan Chowdhury, Ahmed Jalal and Sharif, K. M. and Hossain, Md Sohrab (2014) Particle formation and micronization using non-conventional techniques- review. Chemical Engineering and Processing: Process Intensification, 86 (2014). pp. 47-52. ISSN 0255-2701 http://www.journals.elsevier.com/chemical-engineering-and-processing-process-intensification/
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
English
topic Q Science (General)
T Technology (General)
spellingShingle Q Science (General)
T Technology (General)
Karim, Fahim Tamzeedul
Sarker, Md. Zaidul Islam
Abu Bakar, Mohd Rushdi
U.M., Salim
Awang, Mohamed
Ferdosh, Sahena
Khan Chowdhury, Ahmed Jalal
Sharif, K. M.
Hossain, Md Sohrab
Particle formation and micronization using non-conventional techniques- review
description Due to growing concerns regarding health, safety and the environment, non-conventional methods for particle formation and micronization that are either solvent-less or use environmentally acceptable solvents such as carbon dioxide have come into favor. Supercritical CO2 (sc CO2) (T > 31.1 'C, P > 7.3 MPa) has been used in food and pharmaceutical industries to minimize the use of organic solvents, produce new food products, produce environmentally superior food products and to process and micronize (0.1–5mm) pharmaceuticals. Control of particle size increases the dissolution rate of drugs into the body. Techniques that use sc CO2 eliminate inherent drawbacks of conventional methods such as thermal or mechanical degradation of the product, poor control of the particle size and morphology, lack of brittleness of some polymers and low encapsulation efficiency. Severaltechniques have been reported for the particle formation and micronization using supercritical fluids that have been successfully scaled up for commercial use. Supercritical CO2 has also been used to develop applications for medicines, essential oils, vitamins, food grade polymers, catalysts and pigments. This review highlights the process mechanism of supercritical fluid based techniques as well as some applications on particle formation and micronization.
format Article
author Karim, Fahim Tamzeedul
Sarker, Md. Zaidul Islam
Abu Bakar, Mohd Rushdi
U.M., Salim
Awang, Mohamed
Ferdosh, Sahena
Khan Chowdhury, Ahmed Jalal
Sharif, K. M.
Hossain, Md Sohrab
author_facet Karim, Fahim Tamzeedul
Sarker, Md. Zaidul Islam
Abu Bakar, Mohd Rushdi
U.M., Salim
Awang, Mohamed
Ferdosh, Sahena
Khan Chowdhury, Ahmed Jalal
Sharif, K. M.
Hossain, Md Sohrab
author_sort Karim, Fahim Tamzeedul
title Particle formation and micronization using non-conventional techniques- review
title_short Particle formation and micronization using non-conventional techniques- review
title_full Particle formation and micronization using non-conventional techniques- review
title_fullStr Particle formation and micronization using non-conventional techniques- review
title_full_unstemmed Particle formation and micronization using non-conventional techniques- review
title_sort particle formation and micronization using non-conventional techniques- review
publisher Elsevier B.V
publishDate 2014
url http://irep.iium.edu.my/38952/1/JSF-paper-2014.pdf
http://irep.iium.edu.my/38952/4/38952_Particle%20formation%20and%20micronization.SCOPUS.pdf
http://irep.iium.edu.my/38952/
http://www.journals.elsevier.com/chemical-engineering-and-processing-process-intensification/
_version_ 1648739677606248448
score 13.223943

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