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The impact of Home Medication Review (HMR) in patients with type 2 Diabetes Mellitus (T2DM) living in rural areas in Kuantan, MALAYSIA

OBJECTIVE: To investigate whether Home Medication Review (HMR) conducted by a pharmacist can improve the clinical indices, quality of life and medication adherence in patients with Type 2 Diabetes Mellitus (T2DM). METHOD: Six month prospective, randomized, controlled study. Adult T2DM patients tak...

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Main Authors: Zin, Che Suraya, Alias, Nor Elina, Ball, Patrick
Format: Conference or Workshop Item
Language:English
Published: 2014
Subjects:
RS Pharmacy and materia medica
Online Access:http://irep.iium.edu.my/36934/1/140616_Ispor_montreal_June_2014.pdf
http://irep.iium.edu.my/36934/
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spelling my.iium.irep.36934 http://irep.iium.edu.my/36934/ The impact of Home Medication Review (HMR) in patients with type 2 Diabetes Mellitus (T2DM) living in rural areas in Kuantan, MALAYSIA Zin, Che Suraya Alias, Nor Elina Ball, Patrick RS Pharmacy and materia medica OBJECTIVE: To investigate whether Home Medication Review (HMR) conducted by a pharmacist can improve the clinical indices, quality of life and medication adherence in patients with Type 2 Diabetes Mellitus (T2DM). METHOD: Six month prospective, randomized, controlled study. Adult T2DM patients taking medications for diabetes for at least two years, with HbA1c>8%, were recruited into the study and randomized to intervention or control. The intervention group received three home visits by a pharmacist (at baseline, 3 months and at 6 months), and one group counselling session with a dietician in addition to the standard medical care. Control group patients only received standard medical care. Primary outcome measures were HbA1c and fasting blood sugar (FBS). Secondary outcome measures include lipid profile (triglycerides, LDL- and HDL-cholesterol); blood pressure (BP); medication adherence (assessed using modified Morisky adherence scale); and quality of life (QoL) assessed using the Short form health survey (SF-36v2). Outcomes were evaluated at baseline, 3 months and at 6 months. RESULT: 73 patients were recruited to the intervention group (38) or the control group (35), with no significant difference identified in baseline parameters. Data was analysed in SPSSv19(IBM) using ANOVA and paired t-test. There were significant improvements from baseline to 6 months in the intervention group in; HbA1c (mean difference (MD) = 1.57, 95% CI[0.88, 2.26], p<0.001); FBS (MD=2.76, 95% CI[0.59,4.94], p=0.009); systolicBP (MD=6.56, 95% CI[0.75,12.36], p=0.022); diastolicBP (MD=4.44, 95% CI[1.11,7.78], p=0.006); triglycerides (MD=0.59, 95% CI[0.24,0.93], p<0.001) and medication adherence (MD=-2.19, 95% CI[-2.73,-1.65], p<0.001). The control group showed no significant changes in outcome measures. QoL improved in the intervention group but declined in controls. CONCLUSION: In this study, HMR conducted by a pharmacist provided significant improvement in health and QoL of patients with Type 2 Diabetes Mellitus. HMR may be beneficial for patients with chronic diseases and for the healthcare system. 2014-06-01 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/36934/1/140616_Ispor_montreal_June_2014.pdf Zin, Che Suraya and Alias, Nor Elina and Ball, Patrick (2014) The impact of Home Medication Review (HMR) in patients with type 2 Diabetes Mellitus (T2DM) living in rural areas in Kuantan, MALAYSIA. In: ISPOR 19th Annual International Meeting, 31st May to 4th June 2014, Palais Des Congres de Montreal, Canada.
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic RS Pharmacy and materia medica
spellingShingle RS Pharmacy and materia medica
Zin, Che Suraya
Alias, Nor Elina
Ball, Patrick
The impact of Home Medication Review (HMR) in patients with type 2 Diabetes Mellitus (T2DM) living in rural areas in Kuantan, MALAYSIA
description OBJECTIVE: To investigate whether Home Medication Review (HMR) conducted by a pharmacist can improve the clinical indices, quality of life and medication adherence in patients with Type 2 Diabetes Mellitus (T2DM). METHOD: Six month prospective, randomized, controlled study. Adult T2DM patients taking medications for diabetes for at least two years, with HbA1c>8%, were recruited into the study and randomized to intervention or control. The intervention group received three home visits by a pharmacist (at baseline, 3 months and at 6 months), and one group counselling session with a dietician in addition to the standard medical care. Control group patients only received standard medical care. Primary outcome measures were HbA1c and fasting blood sugar (FBS). Secondary outcome measures include lipid profile (triglycerides, LDL- and HDL-cholesterol); blood pressure (BP); medication adherence (assessed using modified Morisky adherence scale); and quality of life (QoL) assessed using the Short form health survey (SF-36v2). Outcomes were evaluated at baseline, 3 months and at 6 months. RESULT: 73 patients were recruited to the intervention group (38) or the control group (35), with no significant difference identified in baseline parameters. Data was analysed in SPSSv19(IBM) using ANOVA and paired t-test. There were significant improvements from baseline to 6 months in the intervention group in; HbA1c (mean difference (MD) = 1.57, 95% CI[0.88, 2.26], p<0.001); FBS (MD=2.76, 95% CI[0.59,4.94], p=0.009); systolicBP (MD=6.56, 95% CI[0.75,12.36], p=0.022); diastolicBP (MD=4.44, 95% CI[1.11,7.78], p=0.006); triglycerides (MD=0.59, 95% CI[0.24,0.93], p<0.001) and medication adherence (MD=-2.19, 95% CI[-2.73,-1.65], p<0.001). The control group showed no significant changes in outcome measures. QoL improved in the intervention group but declined in controls. CONCLUSION: In this study, HMR conducted by a pharmacist provided significant improvement in health and QoL of patients with Type 2 Diabetes Mellitus. HMR may be beneficial for patients with chronic diseases and for the healthcare system.
format Conference or Workshop Item
author Zin, Che Suraya
Alias, Nor Elina
Ball, Patrick
author_facet Zin, Che Suraya
Alias, Nor Elina
Ball, Patrick
author_sort Zin, Che Suraya
title The impact of Home Medication Review (HMR) in patients with type 2 Diabetes Mellitus (T2DM) living in rural areas in Kuantan, MALAYSIA
title_short The impact of Home Medication Review (HMR) in patients with type 2 Diabetes Mellitus (T2DM) living in rural areas in Kuantan, MALAYSIA
title_full The impact of Home Medication Review (HMR) in patients with type 2 Diabetes Mellitus (T2DM) living in rural areas in Kuantan, MALAYSIA
title_fullStr The impact of Home Medication Review (HMR) in patients with type 2 Diabetes Mellitus (T2DM) living in rural areas in Kuantan, MALAYSIA
title_full_unstemmed The impact of Home Medication Review (HMR) in patients with type 2 Diabetes Mellitus (T2DM) living in rural areas in Kuantan, MALAYSIA
title_sort impact of home medication review (hmr) in patients with type 2 diabetes mellitus (t2dm) living in rural areas in kuantan, malaysia
publishDate 2014
url http://irep.iium.edu.my/36934/1/140616_Ispor_montreal_June_2014.pdf
http://irep.iium.edu.my/36934/
_version_ 1643616631198318592
score 13.211869

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