Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions
Infections in critically ill patients are associated with persistently poor clinical outcomes. These patients have severely altered and variable antibiotic pharmacokinetics and are infected by less susceptible pathogens. Antibiotic dosing that does not account for these features is likely to result...
Saved in:
Main Authors: | Roberts, Jason A., Abdul Aziz, Mohd. Hafiz, Lipman, Jeffrey, Mouton, Johan W., Vinks, Alexander A., Felton, Timothy W., Hope, William W., Farkas, Andras, Neely , Michael N., Schentag, Jerome J., Drusano, George, Frey, Otto R., Theuretzbacher, Ursula, Kuti, Joseph L. |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2014
|
Subjects: | |
Online Access: | http://irep.iium.edu.my/36783/1/14733099-S1473309914X70702-S1473309914700362-main.pdf http://irep.iium.edu.my/36783/ http://www.thelancet.com/journals/laninf/article/PIIS1473-3099%2814%2970036-2/abstract |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Applying pharmacokinetic/pharmacodynamic
principles in critically ill patients: optimizing
efficacy and reducing resistance development
by: Abdul Aziz, Mohd. Hafiz, et al.
Published: (2015) -
What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients?
by: Alobaid, Abdulaziz S., et al.
Published: (2015) -
Identifying “at-risk” patients for sub-optimal beta-lactam exposure in critically ill patients with severe infections
by: Abdul Aziz, Mohd. Hafiz, et al.
Published: (2017) -
Continuous beta-lactam infusion in critically ill patients: the clinical evidence
by: Abdul Aziz, Mohd. Hafiz, et al.
Published: (2012) -
Plasma & subcutaneous tissue pharmacokinetics of piperacillin in a large cohort of critically ill patients with sepsis
by: Abdul Aziz, Mohd. Hafiz, et al.
Published: (2014)