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Torbangun (Coleus amboinicus Lour) extracts affect microbial and fungus activities

Coleus also known as Torbangun or Ati Ati plants leaves i.e. Coleus amboinicus Lour from Indonesia (CAL-I) and Coleus aromaticus (CAT-M), Pogostemon cablin (PC-M), Coleus blumei–red leaves (CBR-M), Coleus amboinicus– (CAL-M) Coleus blumei –purple leaves (CBP-M) from Malaysia were collected, freeze d...

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Main Authors: Khattak, Muhammad Muzaffar Ali Khan, Bakhtiar, M. Taher, Damanik, Muhammad Rizal Martua, Abdul Rahman, Suzanah, Abu Bakar, Ibrahim, Yahaya, Azhary
Format: Article
Language:English
Published: Lifescience Global 2013
Subjects:
RS Pharmacy and materia medica
Online Access:http://irep.iium.edu.my/33816/1/JNTV2N4A3-Khattak.pdf
http://irep.iium.edu.my/33816/
http://www.lifescienceglobal.com/journals/journal-of-nutritional-therapeutics
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spelling my.iium.irep.338162014-12-08T09:46:52Z http://irep.iium.edu.my/33816/ Torbangun (Coleus amboinicus Lour) extracts affect microbial and fungus activities Khattak, Muhammad Muzaffar Ali Khan Bakhtiar, M. Taher Damanik, Muhammad Rizal Martua Abdul Rahman, Suzanah Abu Bakar, Ibrahim Yahaya, Azhary RS Pharmacy and materia medica Coleus also known as Torbangun or Ati Ati plants leaves i.e. Coleus amboinicus Lour from Indonesia (CAL-I) and Coleus aromaticus (CAT-M), Pogostemon cablin (PC-M), Coleus blumei–red leaves (CBR-M), Coleus amboinicus– (CAL-M) Coleus blumei –purple leaves (CBP-M) from Malaysia were collected, freeze dried and extracted with aqueous methanol. The effect of the extract was assessed on microbial and fungal activities in relation to their phytochemicals and antioxidants concentrations. The total phenolic content was determined according to the Folin-Ciocalteu method whilst antioxidant activity was assessed using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) method. The anti-microbial and anti-fungal activities were assessed by minimum inhibitory concentrations (MIC) and disc diffusion methods. The result indicates that the extracts are rich sources of phytochemicals and antioxidants from the listed plants. When the effect of the extracts was assessed on microbial and fungal activities it was observed that the effect was more pronounced on the gram-positive bacteria compared to gram-negative bacteria. Furthermore, there was strong association between phytochemicals and antioxidants concentration and with the microbial and fungal activities. However, it was not consistent for all types of strains. This study shows that Torbangun plants extracts are rich in phenolic contents therefore; it can be used as free radical scavengers and antimicrobial agent apart from other traditional uses. Lifescience Global 2013 Article REM application/pdf en http://irep.iium.edu.my/33816/1/JNTV2N4A3-Khattak.pdf Khattak, Muhammad Muzaffar Ali Khan and Bakhtiar, M. Taher and Damanik, Muhammad Rizal Martua and Abdul Rahman, Suzanah and Abu Bakar, Ibrahim and Yahaya, Azhary (2013) Torbangun (Coleus amboinicus Lour) extracts affect microbial and fungus activities. Journal of Nutritional Therapeutics , 2 (4). pp. 194-200. ISSN 1929-5634 http://www.lifescienceglobal.com/journals/journal-of-nutritional-therapeutics
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic RS Pharmacy and materia medica
spellingShingle RS Pharmacy and materia medica
Khattak, Muhammad Muzaffar Ali Khan
Bakhtiar, M. Taher
Damanik, Muhammad Rizal Martua
Abdul Rahman, Suzanah
Abu Bakar, Ibrahim
Yahaya, Azhary
Torbangun (Coleus amboinicus Lour) extracts affect microbial and fungus activities
description Coleus also known as Torbangun or Ati Ati plants leaves i.e. Coleus amboinicus Lour from Indonesia (CAL-I) and Coleus aromaticus (CAT-M), Pogostemon cablin (PC-M), Coleus blumei–red leaves (CBR-M), Coleus amboinicus– (CAL-M) Coleus blumei –purple leaves (CBP-M) from Malaysia were collected, freeze dried and extracted with aqueous methanol. The effect of the extract was assessed on microbial and fungal activities in relation to their phytochemicals and antioxidants concentrations. The total phenolic content was determined according to the Folin-Ciocalteu method whilst antioxidant activity was assessed using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) method. The anti-microbial and anti-fungal activities were assessed by minimum inhibitory concentrations (MIC) and disc diffusion methods. The result indicates that the extracts are rich sources of phytochemicals and antioxidants from the listed plants. When the effect of the extracts was assessed on microbial and fungal activities it was observed that the effect was more pronounced on the gram-positive bacteria compared to gram-negative bacteria. Furthermore, there was strong association between phytochemicals and antioxidants concentration and with the microbial and fungal activities. However, it was not consistent for all types of strains. This study shows that Torbangun plants extracts are rich in phenolic contents therefore; it can be used as free radical scavengers and antimicrobial agent apart from other traditional uses.
format Article
author Khattak, Muhammad Muzaffar Ali Khan
Bakhtiar, M. Taher
Damanik, Muhammad Rizal Martua
Abdul Rahman, Suzanah
Abu Bakar, Ibrahim
Yahaya, Azhary
author_facet Khattak, Muhammad Muzaffar Ali Khan
Bakhtiar, M. Taher
Damanik, Muhammad Rizal Martua
Abdul Rahman, Suzanah
Abu Bakar, Ibrahim
Yahaya, Azhary
author_sort Khattak, Muhammad Muzaffar Ali Khan
title Torbangun (Coleus amboinicus Lour) extracts affect microbial and fungus activities
title_short Torbangun (Coleus amboinicus Lour) extracts affect microbial and fungus activities
title_full Torbangun (Coleus amboinicus Lour) extracts affect microbial and fungus activities
title_fullStr Torbangun (Coleus amboinicus Lour) extracts affect microbial and fungus activities
title_full_unstemmed Torbangun (Coleus amboinicus Lour) extracts affect microbial and fungus activities
title_sort torbangun (coleus amboinicus lour) extracts affect microbial and fungus activities
publisher Lifescience Global
publishDate 2013
url http://irep.iium.edu.my/33816/1/JNTV2N4A3-Khattak.pdf
http://irep.iium.edu.my/33816/
http://www.lifescienceglobal.com/journals/journal-of-nutritional-therapeutics
_version_ 1643610521420693504
score 13.211869

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