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Current status of coronary risk factors among rural Malays in Malaysia

Background Coronary heart disease (CHD) is the leading cause of death in Malaysia, despite its status as a developing country. The rural population is thought to be at low risk. Objective To investigate the prevalence of risk factors and global risk profile among rural Malays in Malaysia. Methods...

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Main Authors: Khan, Rahmattullah, Nawawi, Hapizah, Nor, Idris, Noor, Ismail, Karim, Norimah, Arshad, Fatimah, Yusoff, Khalid
Format: Article
Language:English
Published: Lippincott Williams & Wilkins 2002
Subjects:
BF Psychology
Q Science (General)
Online Access:http://irep.iium.edu.my/31562/1/Current_Status_of_Coronary.pdf
http://irep.iium.edu.my/31562/
http://dx.doi.org/10.1097/00043798-200202000-00003
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spelling my.iium.irep.315622017-06-16T02:49:43Z http://irep.iium.edu.my/31562/ Current status of coronary risk factors among rural Malays in Malaysia Khan, Rahmattullah Nawawi, Hapizah Nor, Idris Noor, Ismail Karim, Norimah Arshad, Fatimah Yusoff, Khalid BF Psychology Q Science (General) Background Coronary heart disease (CHD) is the leading cause of death in Malaysia, despite its status as a developing country. The rural population is thought to be at low risk. Objective To investigate the prevalence of risk factors and global risk profile among rural Malays in Malaysia. Methods We studied 609 rural Malay subjects (346 females, 263 males; age range 30–65 years). Blood pressure (BP), body mass index (BMI), waist–hip ratio (WHR), smoking habits and family history of premature CHD were documented. Fasting blood samples were analysed for serum lipids, lipoprotein (a), plasma glucose and fibrinogen. Oral glucose tolerance tests were performed using 75 g anhydrous glucose. Results The prevalence of hypercholesterolemia for total cholesterol concentrations of ≥ 5.2, ≥6.5 and ≥7.8 mmol/l were 67.3, 30.5 and 11.8% respectively. There was a high prevalence of low serum high-density lipoprotein cholesterol (13.1%), hypertension (30.3%), smokers (24.4%), diabetes (6.4%), impaired fasting glucose or glucose tolerance (13.9%), overweight or obesity (44.7%) and increased WHR (48.5%). Global risk assessment showed that 67.3% of the study population were at risk, with 15.9, 18.9 and 32.5% in the mild, moderate and high risk categories respectively. Conclusion Prevalence of risk factors was high in the rural population. Global risk assessment showed a high-risk profile with two-thirds being at risk, and one-third being categorized into the high-risk group. Although rural communities were considered at low risk of developing CHD, this is changing fast, possibly due to the rapid socio-economic development, in addition to underlying genetic predisposition. Lippincott Williams & Wilkins 2002-02 Article REM application/pdf en http://irep.iium.edu.my/31562/1/Current_Status_of_Coronary.pdf Khan, Rahmattullah and Nawawi, Hapizah and Nor, Idris and Noor, Ismail and Karim, Norimah and Arshad, Fatimah and Yusoff, Khalid (2002) Current status of coronary risk factors among rural Malays in Malaysia. Journal of Cardiovascular Risk, 9 (1). pp. 17-23. ISSN 1350-6277 http://dx.doi.org/10.1097/00043798-200202000-00003 doi:10.1097/00043798-200202000-00003
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic BF Psychology
Q Science (General)
spellingShingle BF Psychology
Q Science (General)
Khan, Rahmattullah
Nawawi, Hapizah
Nor, Idris
Noor, Ismail
Karim, Norimah
Arshad, Fatimah
Yusoff, Khalid
Current status of coronary risk factors among rural Malays in Malaysia
description Background Coronary heart disease (CHD) is the leading cause of death in Malaysia, despite its status as a developing country. The rural population is thought to be at low risk. Objective To investigate the prevalence of risk factors and global risk profile among rural Malays in Malaysia. Methods We studied 609 rural Malay subjects (346 females, 263 males; age range 30–65 years). Blood pressure (BP), body mass index (BMI), waist–hip ratio (WHR), smoking habits and family history of premature CHD were documented. Fasting blood samples were analysed for serum lipids, lipoprotein (a), plasma glucose and fibrinogen. Oral glucose tolerance tests were performed using 75 g anhydrous glucose. Results The prevalence of hypercholesterolemia for total cholesterol concentrations of ≥ 5.2, ≥6.5 and ≥7.8 mmol/l were 67.3, 30.5 and 11.8% respectively. There was a high prevalence of low serum high-density lipoprotein cholesterol (13.1%), hypertension (30.3%), smokers (24.4%), diabetes (6.4%), impaired fasting glucose or glucose tolerance (13.9%), overweight or obesity (44.7%) and increased WHR (48.5%). Global risk assessment showed that 67.3% of the study population were at risk, with 15.9, 18.9 and 32.5% in the mild, moderate and high risk categories respectively. Conclusion Prevalence of risk factors was high in the rural population. Global risk assessment showed a high-risk profile with two-thirds being at risk, and one-third being categorized into the high-risk group. Although rural communities were considered at low risk of developing CHD, this is changing fast, possibly due to the rapid socio-economic development, in addition to underlying genetic predisposition.
format Article
author Khan, Rahmattullah
Nawawi, Hapizah
Nor, Idris
Noor, Ismail
Karim, Norimah
Arshad, Fatimah
Yusoff, Khalid
author_facet Khan, Rahmattullah
Nawawi, Hapizah
Nor, Idris
Noor, Ismail
Karim, Norimah
Arshad, Fatimah
Yusoff, Khalid
author_sort Khan, Rahmattullah
title Current status of coronary risk factors among rural Malays in Malaysia
title_short Current status of coronary risk factors among rural Malays in Malaysia
title_full Current status of coronary risk factors among rural Malays in Malaysia
title_fullStr Current status of coronary risk factors among rural Malays in Malaysia
title_full_unstemmed Current status of coronary risk factors among rural Malays in Malaysia
title_sort current status of coronary risk factors among rural malays in malaysia
publisher Lippincott Williams & Wilkins
publishDate 2002
url http://irep.iium.edu.my/31562/1/Current_Status_of_Coronary.pdf
http://irep.iium.edu.my/31562/
http://dx.doi.org/10.1097/00043798-200202000-00003
_version_ 1643610041051250688
score 13.211869

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