Cover Image

A randomized double blind placebo-control trial on safety and efficacy of Viva QS for smoking cessation in Malaysian adult population

Introduction: Nicotine dependence is a life threatening disorder and efforts have been focused to identify new mechanisms to assist smokers to quit. The need to find new interventions is vital. The use of herbals as alternative to current treatments is limited and most studies were without randomize...

Full description

Saved in:
Bibliographic Details
Main Authors: Mohamad Noor, Zaswiza, Nik Mohamed, Mohamad Haniki, Md Aris, Mohd Aznan, Draman, Samsul, Shaik Rahman Bux, Siti Halimah Bux, Abd Rahman, Norny Syafinaz
Format: Conference or Workshop Item
Language:English
English
English
Published: 2009
Subjects:
RS Pharmacy and materia medica
Online Access:http://irep.iium.edu.my/28401/1/Abstract_ZASWIZA_M_NOOR_ACCP9Seoul_Korea.pdf
http://irep.iium.edu.my/28401/4/Certificate_ACCP_2009.pdf
http://irep.iium.edu.my/28401/6/accp9posterprogram_zaswiza_P017.pdf
http://irep.iium.edu.my/28401/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.iium.irep.28401
record_format dspace
spelling my.iium.irep.284012014-03-16T17:33:06Z http://irep.iium.edu.my/28401/ A randomized double blind placebo-control trial on safety and efficacy of Viva QS for smoking cessation in Malaysian adult population Mohamad Noor, Zaswiza Nik Mohamed, Mohamad Haniki Md Aris, Mohd Aznan Draman, Samsul Shaik Rahman Bux, Siti Halimah Bux Abd Rahman, Norny Syafinaz RS Pharmacy and materia medica Introduction: Nicotine dependence is a life threatening disorder and efforts have been focused to identify new mechanisms to assist smokers to quit. The need to find new interventions is vital. The use of herbals as alternative to current treatments is limited and most studies were without randomized control trial (RCT). To our knowledge, this is the first study in Malaysia using RCT to study herbal medication for smoking cessation. Viva® was introduced in Malaysia to help drug addicts managed withdrawal symptoms. Distaste for cigarettes were noticed in patients undergoing treatment - which led to development of Viva QS® for smoking cessation. Objectives: The objectives of the study were to determine the effectiveness and safety of Viva QS® for quit smoking using randomized double blind placebo-control trial. Method: We conducted mobile smoking cessation programmes (MSCP) to recruit subjects. We reached smokers at workplaces and recruited those attended smoking cessation talks, fulfilled the eligible criteria and agreed to give consent. Demographic and smoking history information, modified Fagerström test score and carbon monoxide level were obtained at baseline. Subjects were randomly assigned to either Viva QS® or placebo groups. Follow-ups were undertaken by phone call and/or face-to-face meeting. Study medication was consumed for six months. Results: Biochemically verified 7-days point prevalence abstinence at week 24 showed significant difference in quit rates between both groups (Viva QS®, 30.7%; placebo, 13.9%; P = 0.015). Significant differences in quit rates between groups were showed in 7-days point prevalence abstinence at week 4 (Viva QS®, 42.7%; placebo, 26.2%; P = 0.038) and week 12 (Viva QS®, 32.0%; placebo, 16.7%; P = 0.031). Adverse events reported showed no difference in both groups with all mean less than 0.065 (slight effects). Conclusions: We suggested Viva QS® as safe and effective for smoking cessation. Further studies should be undertaken in different population samples to assess the effectiveness and safety of the medication to strengthen our findings. Keywords: Safety, Efficacy, herbal, smoking cessation, pharmacotherapy, counselling. 2009 Conference or Workshop Item REM application/pdf en http://irep.iium.edu.my/28401/1/Abstract_ZASWIZA_M_NOOR_ACCP9Seoul_Korea.pdf application/pdf en http://irep.iium.edu.my/28401/4/Certificate_ACCP_2009.pdf application/pdf en http://irep.iium.edu.my/28401/6/accp9posterprogram_zaswiza_P017.pdf Mohamad Noor, Zaswiza and Nik Mohamed, Mohamad Haniki and Md Aris, Mohd Aznan and Draman, Samsul and Shaik Rahman Bux, Siti Halimah Bux and Abd Rahman, Norny Syafinaz (2009) A randomized double blind placebo-control trial on safety and efficacy of Viva QS for smoking cessation in Malaysian adult population. In: The 9th Asian Conference on Clinical Pharmacy (ACCP9), 26-28 Sept 2009, COEX, Seoul, Korea. (Unpublished)
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
English
English
topic RS Pharmacy and materia medica
spellingShingle RS Pharmacy and materia medica
Mohamad Noor, Zaswiza
Nik Mohamed, Mohamad Haniki
Md Aris, Mohd Aznan
Draman, Samsul
Shaik Rahman Bux, Siti Halimah Bux
Abd Rahman, Norny Syafinaz
A randomized double blind placebo-control trial on safety and efficacy of Viva QS for smoking cessation in Malaysian adult population
description Introduction: Nicotine dependence is a life threatening disorder and efforts have been focused to identify new mechanisms to assist smokers to quit. The need to find new interventions is vital. The use of herbals as alternative to current treatments is limited and most studies were without randomized control trial (RCT). To our knowledge, this is the first study in Malaysia using RCT to study herbal medication for smoking cessation. Viva® was introduced in Malaysia to help drug addicts managed withdrawal symptoms. Distaste for cigarettes were noticed in patients undergoing treatment - which led to development of Viva QS® for smoking cessation. Objectives: The objectives of the study were to determine the effectiveness and safety of Viva QS® for quit smoking using randomized double blind placebo-control trial. Method: We conducted mobile smoking cessation programmes (MSCP) to recruit subjects. We reached smokers at workplaces and recruited those attended smoking cessation talks, fulfilled the eligible criteria and agreed to give consent. Demographic and smoking history information, modified Fagerström test score and carbon monoxide level were obtained at baseline. Subjects were randomly assigned to either Viva QS® or placebo groups. Follow-ups were undertaken by phone call and/or face-to-face meeting. Study medication was consumed for six months. Results: Biochemically verified 7-days point prevalence abstinence at week 24 showed significant difference in quit rates between both groups (Viva QS®, 30.7%; placebo, 13.9%; P = 0.015). Significant differences in quit rates between groups were showed in 7-days point prevalence abstinence at week 4 (Viva QS®, 42.7%; placebo, 26.2%; P = 0.038) and week 12 (Viva QS®, 32.0%; placebo, 16.7%; P = 0.031). Adverse events reported showed no difference in both groups with all mean less than 0.065 (slight effects). Conclusions: We suggested Viva QS® as safe and effective for smoking cessation. Further studies should be undertaken in different population samples to assess the effectiveness and safety of the medication to strengthen our findings. Keywords: Safety, Efficacy, herbal, smoking cessation, pharmacotherapy, counselling.
format Conference or Workshop Item
author Mohamad Noor, Zaswiza
Nik Mohamed, Mohamad Haniki
Md Aris, Mohd Aznan
Draman, Samsul
Shaik Rahman Bux, Siti Halimah Bux
Abd Rahman, Norny Syafinaz
author_facet Mohamad Noor, Zaswiza
Nik Mohamed, Mohamad Haniki
Md Aris, Mohd Aznan
Draman, Samsul
Shaik Rahman Bux, Siti Halimah Bux
Abd Rahman, Norny Syafinaz
author_sort Mohamad Noor, Zaswiza
title A randomized double blind placebo-control trial on safety and efficacy of Viva QS for smoking cessation in Malaysian adult population
title_short A randomized double blind placebo-control trial on safety and efficacy of Viva QS for smoking cessation in Malaysian adult population
title_full A randomized double blind placebo-control trial on safety and efficacy of Viva QS for smoking cessation in Malaysian adult population
title_fullStr A randomized double blind placebo-control trial on safety and efficacy of Viva QS for smoking cessation in Malaysian adult population
title_full_unstemmed A randomized double blind placebo-control trial on safety and efficacy of Viva QS for smoking cessation in Malaysian adult population
title_sort randomized double blind placebo-control trial on safety and efficacy of viva qs for smoking cessation in malaysian adult population
publishDate 2009
url http://irep.iium.edu.my/28401/1/Abstract_ZASWIZA_M_NOOR_ACCP9Seoul_Korea.pdf
http://irep.iium.edu.my/28401/4/Certificate_ACCP_2009.pdf
http://irep.iium.edu.my/28401/6/accp9posterprogram_zaswiza_P017.pdf
http://irep.iium.edu.my/28401/
_version_ 1643609497124470784
score 13.211869

Similar Items