COX-2 inhibitors: a potential target for drug therapy in the management of colorectal cancer
Colorectal cancer is currently the third most common cancer in Malaysia. Elevated expression of COX-2, an induced cyclooxygenase isoenzyme, has been seen in colonic adenomas and colorectal carcinoma. There is evidence that inhibition of this COX-2 can decrease the risk of colorectal cancer. Selectiv...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Malaysian Medical Association
1999
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/23984/1/COX-2_Inhibitors_-_A_Potential_Target_for_Drug_Therapy_in_the_Management_of_Colorectal_Cancer.pdf http://irep.iium.edu.my/23984/ http://www.e-mjm.org/index.html |
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| Summary: | Colorectal cancer is currently the third most common cancer in Malaysia. Elevated expression of COX-2, an induced cyclooxygenase isoenzyme, has been seen in colonic adenomas and colorectal carcinoma. There is evidence that inhibition of this COX-2 can decrease the risk of colorectal cancer. Selective COX-2 inhibitors may have a role in reducing the risk of colorectal cancer in high-risk individuals. |
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