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Antimicrobial activity and essential oils of Curcuma aeruginosa, Curcuma mangga, and Zingiber cassumunar from Malaysia

OBJECTIVE: To analyze the chemical composition of the essential oils of Curcuma aeruginosa (C. aeruginosa), Curcuma mangga (C. mangga), and Zingiber cassumunar (Z. cassumunar), and study their antimicrobial activity. METHODS: Essential oils obtained by steam distillation were analyzed by gas chro...

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Main Authors: Tg Kamazeri, Tg Siti Amirah, Abd. Samah, Othman, Bakhtiar, M. Taher, Darnis, Deny Susanti, Qaralleh, Haitham
Format: Article
Language:English
Published: Elsevier 2012
Subjects:
QR Microbiology
Online Access:http://irep.iium.edu.my/23311/1/Tg_Siti_Amirah_-_APJTM_Published_Article.pdf
http://irep.iium.edu.my/23311/
http://dx.doi.org/10.1016/S1995-7645(12)60025-X
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spelling my.iium.irep.233112012-05-16T01:29:46Z http://irep.iium.edu.my/23311/ Antimicrobial activity and essential oils of Curcuma aeruginosa, Curcuma mangga, and Zingiber cassumunar from Malaysia Tg Kamazeri, Tg Siti Amirah Abd. Samah, Othman Bakhtiar, M. Taher Darnis, Deny Susanti Qaralleh, Haitham QR Microbiology OBJECTIVE: To analyze the chemical composition of the essential oils of Curcuma aeruginosa (C. aeruginosa), Curcuma mangga (C. mangga), and Zingiber cassumunar (Z. cassumunar), and study their antimicrobial activity. METHODS: Essential oils obtained by steam distillation were analyzed by gas chromatography-mass spectrometry (GC-MS). The antimicrobial activity of the essential oils was evaluated against four bacteria: Bacillus cereus (B. cereus), Staphylococcus aureus (S. aureus), Escherichia coli (E. coli), and Pseudomonas aeruginosa (P. aeruginosa); and two fungi: Candida albicans (C. albicans) and Cyptococcus neoformans (C. neoformans), using disc-diffusion and broth microdilution methods. RESULTS: Cycloisolongifolene, 8,9-dehydro formyl (35.29%) and dihydrocostunolide (22.51%) were the major compounds in C. aeruginosa oil; whereas caryophyllene oxide (18.71%) and caryophyllene (12.69%) were the major compounds in C. mangga oil; and 2,6,9,9-tetramethyl-2,6,10-cycloundecatrien-1-one (60.77%) and α-caryophyllene (23.92%) were abundant in Z. cassumunar oil. The essential oils displayed varying degrees of antimicrobial activity against all tested microorganisms. C. mangga oil had the highest and most broad-spectrum activity by inhibiting all microorganisms tested, with C. neoformans being the most sensitive microorganism by having the lowest minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) values of 0.1 μL/mL. C. aeruginosa oil showed mild antimicrobial activity, whereas Z. cassumunar had very low or weak activity against the tested microorganisms. CONCLUSIONS: The preliminary results suggest promising antimicrobial properties of C. mangga and C. aeruginosa, which may be useful for food preservation, pharmaceutical treatment and natural therapies Elsevier 2012 Article REM application/pdf en http://irep.iium.edu.my/23311/1/Tg_Siti_Amirah_-_APJTM_Published_Article.pdf Tg Kamazeri, Tg Siti Amirah and Abd. Samah, Othman and Bakhtiar, M. Taher and Darnis, Deny Susanti and Qaralleh, Haitham (2012) Antimicrobial activity and essential oils of Curcuma aeruginosa, Curcuma mangga, and Zingiber cassumunar from Malaysia. Asian Pacific Journal of Tropical Medicine, 5 (3). pp. 202-209. ISSN 1995-7645 http://dx.doi.org/10.1016/S1995-7645(12)60025-X doi:10.1016/S1995-7645(12)60025-X
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic QR Microbiology
spellingShingle QR Microbiology
Tg Kamazeri, Tg Siti Amirah
Abd. Samah, Othman
Bakhtiar, M. Taher
Darnis, Deny Susanti
Qaralleh, Haitham
Antimicrobial activity and essential oils of Curcuma aeruginosa, Curcuma mangga, and Zingiber cassumunar from Malaysia
description OBJECTIVE: To analyze the chemical composition of the essential oils of Curcuma aeruginosa (C. aeruginosa), Curcuma mangga (C. mangga), and Zingiber cassumunar (Z. cassumunar), and study their antimicrobial activity. METHODS: Essential oils obtained by steam distillation were analyzed by gas chromatography-mass spectrometry (GC-MS). The antimicrobial activity of the essential oils was evaluated against four bacteria: Bacillus cereus (B. cereus), Staphylococcus aureus (S. aureus), Escherichia coli (E. coli), and Pseudomonas aeruginosa (P. aeruginosa); and two fungi: Candida albicans (C. albicans) and Cyptococcus neoformans (C. neoformans), using disc-diffusion and broth microdilution methods. RESULTS: Cycloisolongifolene, 8,9-dehydro formyl (35.29%) and dihydrocostunolide (22.51%) were the major compounds in C. aeruginosa oil; whereas caryophyllene oxide (18.71%) and caryophyllene (12.69%) were the major compounds in C. mangga oil; and 2,6,9,9-tetramethyl-2,6,10-cycloundecatrien-1-one (60.77%) and α-caryophyllene (23.92%) were abundant in Z. cassumunar oil. The essential oils displayed varying degrees of antimicrobial activity against all tested microorganisms. C. mangga oil had the highest and most broad-spectrum activity by inhibiting all microorganisms tested, with C. neoformans being the most sensitive microorganism by having the lowest minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) values of 0.1 μL/mL. C. aeruginosa oil showed mild antimicrobial activity, whereas Z. cassumunar had very low or weak activity against the tested microorganisms. CONCLUSIONS: The preliminary results suggest promising antimicrobial properties of C. mangga and C. aeruginosa, which may be useful for food preservation, pharmaceutical treatment and natural therapies
format Article
author Tg Kamazeri, Tg Siti Amirah
Abd. Samah, Othman
Bakhtiar, M. Taher
Darnis, Deny Susanti
Qaralleh, Haitham
author_facet Tg Kamazeri, Tg Siti Amirah
Abd. Samah, Othman
Bakhtiar, M. Taher
Darnis, Deny Susanti
Qaralleh, Haitham
author_sort Tg Kamazeri, Tg Siti Amirah
title Antimicrobial activity and essential oils of Curcuma aeruginosa, Curcuma mangga, and Zingiber cassumunar from Malaysia
title_short Antimicrobial activity and essential oils of Curcuma aeruginosa, Curcuma mangga, and Zingiber cassumunar from Malaysia
title_full Antimicrobial activity and essential oils of Curcuma aeruginosa, Curcuma mangga, and Zingiber cassumunar from Malaysia
title_fullStr Antimicrobial activity and essential oils of Curcuma aeruginosa, Curcuma mangga, and Zingiber cassumunar from Malaysia
title_full_unstemmed Antimicrobial activity and essential oils of Curcuma aeruginosa, Curcuma mangga, and Zingiber cassumunar from Malaysia
title_sort antimicrobial activity and essential oils of curcuma aeruginosa, curcuma mangga, and zingiber cassumunar from malaysia
publisher Elsevier
publishDate 2012
url http://irep.iium.edu.my/23311/1/Tg_Siti_Amirah_-_APJTM_Published_Article.pdf
http://irep.iium.edu.my/23311/
http://dx.doi.org/10.1016/S1995-7645(12)60025-X
_version_ 1643608560558407680
score 13.211869

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