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Determination of octanol-water partition coefficients of anti-microbial alkaloids from Glycosmis pentaphylla (Retz) DC

Octanol-water partition coefficient (KOW) values of anti-microbial alkaloids, arborine and arborinine of Glycosmis pentaphylla (Retz) DC were determined. The method of extraction by solvents of these alkaloids and the following isolation procedures using column chromatography techniques will adopt t...

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Main Authors: Ahmad, Kausar, Mohd Hassan, Norazian, Helal Uddin, A.B.M., Mat Ali, Idura, Mansor, Norhafizah
Format: Conference or Workshop Item
Language:English
Published: 2010
Subjects:
R Medicine (General)
RB Pathology
Online Access:http://irep.iium.edu.my/21201/1/Detrmination_of_octanol-water.pdf
http://irep.iium.edu.my/21201/
http://www.iium.edu.my/icast/2010/index.php?option=com_content&view=article&id=14&Itemid=17
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spelling my.iium.irep.212012022-12-09T02:54:06Z http://irep.iium.edu.my/21201/ Determination of octanol-water partition coefficients of anti-microbial alkaloids from Glycosmis pentaphylla (Retz) DC Ahmad, Kausar Mohd Hassan, Norazian Helal Uddin, A.B.M. Mat Ali, Idura Mansor, Norhafizah R Medicine (General) RB Pathology Octanol-water partition coefficient (KOW) values of anti-microbial alkaloids, arborine and arborinine of Glycosmis pentaphylla (Retz) DC were determined. The method of extraction by solvents of these alkaloids and the following isolation procedures using column chromatography techniques will adopt those ascertained and established earlier (Norazian, 2006). A shake-flask method was used to determine the octanol-water partition coefficients from (298.15, 303.15, 308.15 and 313.15)k. Each compound was dissolved in the octanol to a known concentration and placed in octanol-water system and allowed to equilibrate. The concentration in the octanol phase was then determined by using spectrophotometer. The KOW was calculated as the ratio of the concentration in octanol phase to the concentration in aqueous phase. 2010 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/21201/1/Detrmination_of_octanol-water.pdf Ahmad, Kausar and Mohd Hassan, Norazian and Helal Uddin, A.B.M. and Mat Ali, Idura and Mansor, Norhafizah (2010) Determination of octanol-water partition coefficients of anti-microbial alkaloids from Glycosmis pentaphylla (Retz) DC. In: 3rd International Conference on Advancement in Science and Technology (iCAST) 2010, 27-29 November 2010, Vistana Hotel, Kuantan, Pahang. http://www.iium.edu.my/icast/2010/index.php?option=com_content&view=article&id=14&Itemid=17
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic R Medicine (General)
RB Pathology
spellingShingle R Medicine (General)
RB Pathology
Ahmad, Kausar
Mohd Hassan, Norazian
Helal Uddin, A.B.M.
Mat Ali, Idura
Mansor, Norhafizah
Determination of octanol-water partition coefficients of anti-microbial alkaloids from Glycosmis pentaphylla (Retz) DC
description Octanol-water partition coefficient (KOW) values of anti-microbial alkaloids, arborine and arborinine of Glycosmis pentaphylla (Retz) DC were determined. The method of extraction by solvents of these alkaloids and the following isolation procedures using column chromatography techniques will adopt those ascertained and established earlier (Norazian, 2006). A shake-flask method was used to determine the octanol-water partition coefficients from (298.15, 303.15, 308.15 and 313.15)k. Each compound was dissolved in the octanol to a known concentration and placed in octanol-water system and allowed to equilibrate. The concentration in the octanol phase was then determined by using spectrophotometer. The KOW was calculated as the ratio of the concentration in octanol phase to the concentration in aqueous phase.
format Conference or Workshop Item
author Ahmad, Kausar
Mohd Hassan, Norazian
Helal Uddin, A.B.M.
Mat Ali, Idura
Mansor, Norhafizah
author_facet Ahmad, Kausar
Mohd Hassan, Norazian
Helal Uddin, A.B.M.
Mat Ali, Idura
Mansor, Norhafizah
author_sort Ahmad, Kausar
title Determination of octanol-water partition coefficients of anti-microbial alkaloids from Glycosmis pentaphylla (Retz) DC
title_short Determination of octanol-water partition coefficients of anti-microbial alkaloids from Glycosmis pentaphylla (Retz) DC
title_full Determination of octanol-water partition coefficients of anti-microbial alkaloids from Glycosmis pentaphylla (Retz) DC
title_fullStr Determination of octanol-water partition coefficients of anti-microbial alkaloids from Glycosmis pentaphylla (Retz) DC
title_full_unstemmed Determination of octanol-water partition coefficients of anti-microbial alkaloids from Glycosmis pentaphylla (Retz) DC
title_sort determination of octanol-water partition coefficients of anti-microbial alkaloids from glycosmis pentaphylla (retz) dc
publishDate 2010
url http://irep.iium.edu.my/21201/1/Detrmination_of_octanol-water.pdf
http://irep.iium.edu.my/21201/
http://www.iium.edu.my/icast/2010/index.php?option=com_content&view=article&id=14&Itemid=17
_version_ 1752146269049978880
score 13.211869

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