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Anti-inflammatory compounds of macro algae origin: A review

Inflammation, occurs frequently in living tissues, and is responsible for numerous death and precursor to some deadly diseases. This review focus on seaweed derived anti-inflammatory compounds, which have attracted interest and promising replacer of current anti-inflammatory drugs. Macro algae hav...

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Main Authors: Jaswir, Irwandi, A. Monsur, Hammed
Format: Article
Language:English
Published: Academic Journals 2011
Subjects:
QD Chemistry
Online Access:http://irep.iium.edu.my/17155/1/Jaswir_and_Monsur-jmpr_2011.pdf
http://irep.iium.edu.my/17155/
http://www.academicjournals.org/JMPR/PDF/pdf2011/31Dec/Jaswir%20and%20Monsur.pdf
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spelling my.iium.irep.171552016-08-24T00:55:50Z http://irep.iium.edu.my/17155/ Anti-inflammatory compounds of macro algae origin: A review Jaswir, Irwandi A. Monsur, Hammed QD Chemistry Inflammation, occurs frequently in living tissues, and is responsible for numerous death and precursor to some deadly diseases. This review focus on seaweed derived anti-inflammatory compounds, which have attracted interest and promising replacer of current anti-inflammatory drugs. Macro algae have both pro- and anti-inflammatory compounds, the later include sulphated polysaccharides (fucoidans) from brown seaweeds, alkaloids (Caulerpin I, II and III) from red and green seaweeds, polyunsaturated fatty acids (Docosahexaenoic acid: EDA, Eicosapentaenoic acid: EPA, Stearidonic acid: SA and Eicosatrienoic acid: ETA), carotenoids (fucoxanthin and astaxanthin), Pheophytin A and Vidalols A and B. Anti-inflammatory assays include edema, erythema, tumor necrosis factor (TNF-α), interleukin (IL 1β, 6, 8), Nitric oxide (NO), inducible Nitric oxide synthase (iNOS), Prostaglandin E (PGE 2 and 3), Cyclooxygenase (COX-2), transcription factor (NF-κB) and leukotrienes (LB 3 and 4). Although, in-vivo and in-vitro studies have been done for crude extracts and specific compounds, but some compounds have not analysed in-vitro, and investigation of their pathway need to be studied. Academic Journals 2011-12-31 Article REM application/pdf en http://irep.iium.edu.my/17155/1/Jaswir_and_Monsur-jmpr_2011.pdf Jaswir, Irwandi and A. Monsur, Hammed (2011) Anti-inflammatory compounds of macro algae origin: A review. Journal of Medicinal Plants Research, 5 (33). pp. 7146-7154. ISSN 1996-0875 http://www.academicjournals.org/JMPR/PDF/pdf2011/31Dec/Jaswir%20and%20Monsur.pdf 10.5897/JMPR11.018
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic QD Chemistry
spellingShingle QD Chemistry
Jaswir, Irwandi
A. Monsur, Hammed
Anti-inflammatory compounds of macro algae origin: A review
description Inflammation, occurs frequently in living tissues, and is responsible for numerous death and precursor to some deadly diseases. This review focus on seaweed derived anti-inflammatory compounds, which have attracted interest and promising replacer of current anti-inflammatory drugs. Macro algae have both pro- and anti-inflammatory compounds, the later include sulphated polysaccharides (fucoidans) from brown seaweeds, alkaloids (Caulerpin I, II and III) from red and green seaweeds, polyunsaturated fatty acids (Docosahexaenoic acid: EDA, Eicosapentaenoic acid: EPA, Stearidonic acid: SA and Eicosatrienoic acid: ETA), carotenoids (fucoxanthin and astaxanthin), Pheophytin A and Vidalols A and B. Anti-inflammatory assays include edema, erythema, tumor necrosis factor (TNF-α), interleukin (IL 1β, 6, 8), Nitric oxide (NO), inducible Nitric oxide synthase (iNOS), Prostaglandin E (PGE 2 and 3), Cyclooxygenase (COX-2), transcription factor (NF-κB) and leukotrienes (LB 3 and 4). Although, in-vivo and in-vitro studies have been done for crude extracts and specific compounds, but some compounds have not analysed in-vitro, and investigation of their pathway need to be studied.
format Article
author Jaswir, Irwandi
A. Monsur, Hammed
author_facet Jaswir, Irwandi
A. Monsur, Hammed
author_sort Jaswir, Irwandi
title Anti-inflammatory compounds of macro algae origin: A review
title_short Anti-inflammatory compounds of macro algae origin: A review
title_full Anti-inflammatory compounds of macro algae origin: A review
title_fullStr Anti-inflammatory compounds of macro algae origin: A review
title_full_unstemmed Anti-inflammatory compounds of macro algae origin: A review
title_sort anti-inflammatory compounds of macro algae origin: a review
publisher Academic Journals
publishDate 2011
url http://irep.iium.edu.my/17155/1/Jaswir_and_Monsur-jmpr_2011.pdf
http://irep.iium.edu.my/17155/
http://www.academicjournals.org/JMPR/PDF/pdf2011/31Dec/Jaswir%20and%20Monsur.pdf
_version_ 1643607234490400768
score 13.211869

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