Cover Image

Phytochemicals constituents of Malay traditional medicinal plants as potential remedies for breast cancer: a review

Background: Breast cancer is the most prominent cancer in Malaysia, followed by lung, nasopharyngeal, colorectal, and liver cancers. Data from the World Health Organisation (2020) support the nation's high incidence of breast cancer. Studies have shown that phytochemicals, or secondary plant me...

Full description

Saved in:
Bibliographic Details
Main Authors: Raja Soh, Raja Siti Syazana, Abdull Rasad, Mohammad Syaiful Bahari
Format: Article
Language:English
Published: IIUM Press, International Islamic University Malaysia 2024
Subjects:
TP248.13 Biotechnology
Online Access:http://irep.iium.edu.my/118107/7/118107_Phytochemicals%20constituents%20of%20Malay%20traditional%20medicinal%20plants.pdf
http://irep.iium.edu.my/118107/
https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/931
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.iium.irep.118107
record_format dspace
spelling my.iium.irep.1181072025-01-13T00:53:10Z http://irep.iium.edu.my/118107/ Phytochemicals constituents of Malay traditional medicinal plants as potential remedies for breast cancer: a review Raja Soh, Raja Siti Syazana Abdull Rasad, Mohammad Syaiful Bahari TP248.13 Biotechnology Background: Breast cancer is the most prominent cancer in Malaysia, followed by lung, nasopharyngeal, colorectal, and liver cancers. Data from the World Health Organisation (2020) support the nation's high incidence of breast cancer. Studies have shown that phytochemicals, or secondary plant metabolites, have a promising future as adjuvants for a number of current medicines. The aim of this research is to provide an overview of the phytochemical components identified in traditional Malay medicinal plants that may be used to treat breast cancer in Malaysian women. Methods: The most prominent phytochemicals found Malay traditional medicinal plants with anticancer activities against breast cancer are identified and compiled using a scoping review technique. Scopus, ScienceDirect, and PubMed were the three databases used in the study to search for papers that fit the inclusion and exclusion criteria. The screening approach concentrates on English papers from January 2015 to April 2023, utilising keywords such as the scientific names of the 45 identified plants, "phytochemical," and "breast cancer". Results: Out of 702 screened articles, only 23 met the predetermined criteria and were included in the study. The analysis reveals that 13 Malay traditional medicinal plants show positive outcomes against breast cancer, primarily due to the presence of phenolic compounds in their extract. Conclusions: The study identifies 13 out of 45 selected Malay traditional medicinal plants that exhibit positive outcomes against breast cancer. These plants contain significant phytochemicals such as phenolic compounds, alkaloids, terpenoids, and others, highlighting their potential as therapeutic agents. This comprehensive review is expected to assist researchers in embarking on pre-clinical studies focused on potential Malay traditional plants for breast cancer treatment and further elucidating the pharmacology of these phytomedicines. IIUM Press, International Islamic University Malaysia 2024-12-27 Article PeerReviewed application/pdf en http://irep.iium.edu.my/118107/7/118107_Phytochemicals%20constituents%20of%20Malay%20traditional%20medicinal%20plants.pdf Raja Soh, Raja Siti Syazana and Abdull Rasad, Mohammad Syaiful Bahari (2024) Phytochemicals constituents of Malay traditional medicinal plants as potential remedies for breast cancer: a review. International Journal of Allied Health Sciences, 8 (5). pp. 308-319. E-ISSN 2600-8491 https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/931 10.31436/ijahs.v8i5
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic TP248.13 Biotechnology
spellingShingle TP248.13 Biotechnology
Raja Soh, Raja Siti Syazana
Abdull Rasad, Mohammad Syaiful Bahari
Phytochemicals constituents of Malay traditional medicinal plants as potential remedies for breast cancer: a review
description Background: Breast cancer is the most prominent cancer in Malaysia, followed by lung, nasopharyngeal, colorectal, and liver cancers. Data from the World Health Organisation (2020) support the nation's high incidence of breast cancer. Studies have shown that phytochemicals, or secondary plant metabolites, have a promising future as adjuvants for a number of current medicines. The aim of this research is to provide an overview of the phytochemical components identified in traditional Malay medicinal plants that may be used to treat breast cancer in Malaysian women. Methods: The most prominent phytochemicals found Malay traditional medicinal plants with anticancer activities against breast cancer are identified and compiled using a scoping review technique. Scopus, ScienceDirect, and PubMed were the three databases used in the study to search for papers that fit the inclusion and exclusion criteria. The screening approach concentrates on English papers from January 2015 to April 2023, utilising keywords such as the scientific names of the 45 identified plants, "phytochemical," and "breast cancer". Results: Out of 702 screened articles, only 23 met the predetermined criteria and were included in the study. The analysis reveals that 13 Malay traditional medicinal plants show positive outcomes against breast cancer, primarily due to the presence of phenolic compounds in their extract. Conclusions: The study identifies 13 out of 45 selected Malay traditional medicinal plants that exhibit positive outcomes against breast cancer. These plants contain significant phytochemicals such as phenolic compounds, alkaloids, terpenoids, and others, highlighting their potential as therapeutic agents. This comprehensive review is expected to assist researchers in embarking on pre-clinical studies focused on potential Malay traditional plants for breast cancer treatment and further elucidating the pharmacology of these phytomedicines.
format Article
author Raja Soh, Raja Siti Syazana
Abdull Rasad, Mohammad Syaiful Bahari
author_facet Raja Soh, Raja Siti Syazana
Abdull Rasad, Mohammad Syaiful Bahari
author_sort Raja Soh, Raja Siti Syazana
title Phytochemicals constituents of Malay traditional medicinal plants as potential remedies for breast cancer: a review
title_short Phytochemicals constituents of Malay traditional medicinal plants as potential remedies for breast cancer: a review
title_full Phytochemicals constituents of Malay traditional medicinal plants as potential remedies for breast cancer: a review
title_fullStr Phytochemicals constituents of Malay traditional medicinal plants as potential remedies for breast cancer: a review
title_full_unstemmed Phytochemicals constituents of Malay traditional medicinal plants as potential remedies for breast cancer: a review
title_sort phytochemicals constituents of malay traditional medicinal plants as potential remedies for breast cancer: a review
publisher IIUM Press, International Islamic University Malaysia
publishDate 2024
url http://irep.iium.edu.my/118107/7/118107_Phytochemicals%20constituents%20of%20Malay%20traditional%20medicinal%20plants.pdf
http://irep.iium.edu.my/118107/
https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/931
_version_ 1821105176994381824
score 13.244413

Similar Items