Cover Image

Shingles remedies based on analysis of accordion-folded Malay medical manuscript MSS 3048

Shingles or herpes zoster (HZ) is a painful disease caused by reactivation of latent varicella zoster virus (VZV) in the sensory dorsal root ganglion cells of human body after the primary infection, chickenpox. Currently, there is no drug that can cure it besides for symptoms relief. Therefore, trad...

Full description

Saved in:
Bibliographic Details
Main Authors: Ahmad Radzaudin, Norfarihah, Ahmad Nadzirin, Izzuddin
Format: Article
Language:English
Published: IIUM Press 2024
Subjects:
C Auxiliary sciences of history (General)
P Philology. Linguistics
QH301 Biology
RM Therapeutics. Pharmacology
RM147 Administration of Drugs and Other Therapeutic Agents
RV Botanic, Thomsonian, and eclectic medicine
Online Access:http://irep.iium.edu.my/115935/1/115935_Shingles%20remedies%20based%20on%20analysis%20of%20accordion-folded.pdf
http://irep.iium.edu.my/115935/
https://journals.iium.edu.my/ijahs/index.php/IJAHS/issue/view/36
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.iium.irep.115935
record_format dspace
spelling my.iium.irep.1159352024-11-26T03:01:27Z http://irep.iium.edu.my/115935/ Shingles remedies based on analysis of accordion-folded Malay medical manuscript MSS 3048 Ahmad Radzaudin, Norfarihah Ahmad Nadzirin, Izzuddin C Auxiliary sciences of history (General) P Philology. Linguistics QH301 Biology RM Therapeutics. Pharmacology RM147 Administration of Drugs and Other Therapeutic Agents RV Botanic, Thomsonian, and eclectic medicine Shingles or herpes zoster (HZ) is a painful disease caused by reactivation of latent varicella zoster virus (VZV) in the sensory dorsal root ganglion cells of human body after the primary infection, chickenpox. Currently, there is no drug that can cure it besides for symptoms relief. Therefore, traditional remedies from credible sources such as the Malay medical manuscript MSS 3048 was referred to for getting various valuable medicinal information regarding cure and treatment of shingles disease. A transliterated Malay medical manuscript (MMM) containing remedies on shingles disease was selected, followed by data extraction and tabulation on its formulations and ingredients used. Subsequently, ingredients from the formulations were comparatively analysed against contemporary studies to discover scientific evidence and pharmacological properties that has high potential to be developed as new pharmaceutical products. After evaluation using SAKTI-iPharmaprospect index, the highly scored-formulations were assessed based on comparative analysis to determine the best formulations that can be recommended for further studies. In MSS 3048, 19 formulations were discovered for shingles disease. Data analysis and comparative study on shingles provided information on pharmacological properties of each plant and there were a few plants having high scientific evidences including Annona spp., Piper betel Linn, Schima wallichii, Dipterocarpus spp., Areca catechu, Euphorbia hirta and Quercus infectoria. The use of SAKTI-iPharmaprospect discovered eight Grade A formulations and after assessment with contemporary scientific evidence, three formulations which were F2, F4 and F15 were selected as the best formulations. In conclusion, grade A formulations, F2, F4 and F15 have high potential to be selected for further studies and developed into new pharmaceutical products. The findings from this study may contribute to future laboratory works and research for development of pharmaceutical products for shingles treatment and Traditional and Complementary Medicine (T&CM) in Malaysia. IIUM Press 2024-11-18 Article PeerReviewed application/pdf en http://irep.iium.edu.my/115935/1/115935_Shingles%20remedies%20based%20on%20analysis%20of%20accordion-folded.pdf Ahmad Radzaudin, Norfarihah and Ahmad Nadzirin, Izzuddin (2024) Shingles remedies based on analysis of accordion-folded Malay medical manuscript MSS 3048. International Journal of Allied Health Sciences, 8 (4). pp. 57-74. E-ISSN 2600-8491 https://journals.iium.edu.my/ijahs/index.php/IJAHS/issue/view/36 10.31436/ijahs.v8i4
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic C Auxiliary sciences of history (General)
P Philology. Linguistics
QH301 Biology
RM Therapeutics. Pharmacology
RM147 Administration of Drugs and Other Therapeutic Agents
RV Botanic, Thomsonian, and eclectic medicine
spellingShingle C Auxiliary sciences of history (General)
P Philology. Linguistics
QH301 Biology
RM Therapeutics. Pharmacology
RM147 Administration of Drugs and Other Therapeutic Agents
RV Botanic, Thomsonian, and eclectic medicine
Ahmad Radzaudin, Norfarihah
Ahmad Nadzirin, Izzuddin
Shingles remedies based on analysis of accordion-folded Malay medical manuscript MSS 3048
description Shingles or herpes zoster (HZ) is a painful disease caused by reactivation of latent varicella zoster virus (VZV) in the sensory dorsal root ganglion cells of human body after the primary infection, chickenpox. Currently, there is no drug that can cure it besides for symptoms relief. Therefore, traditional remedies from credible sources such as the Malay medical manuscript MSS 3048 was referred to for getting various valuable medicinal information regarding cure and treatment of shingles disease. A transliterated Malay medical manuscript (MMM) containing remedies on shingles disease was selected, followed by data extraction and tabulation on its formulations and ingredients used. Subsequently, ingredients from the formulations were comparatively analysed against contemporary studies to discover scientific evidence and pharmacological properties that has high potential to be developed as new pharmaceutical products. After evaluation using SAKTI-iPharmaprospect index, the highly scored-formulations were assessed based on comparative analysis to determine the best formulations that can be recommended for further studies. In MSS 3048, 19 formulations were discovered for shingles disease. Data analysis and comparative study on shingles provided information on pharmacological properties of each plant and there were a few plants having high scientific evidences including Annona spp., Piper betel Linn, Schima wallichii, Dipterocarpus spp., Areca catechu, Euphorbia hirta and Quercus infectoria. The use of SAKTI-iPharmaprospect discovered eight Grade A formulations and after assessment with contemporary scientific evidence, three formulations which were F2, F4 and F15 were selected as the best formulations. In conclusion, grade A formulations, F2, F4 and F15 have high potential to be selected for further studies and developed into new pharmaceutical products. The findings from this study may contribute to future laboratory works and research for development of pharmaceutical products for shingles treatment and Traditional and Complementary Medicine (T&CM) in Malaysia.
format Article
author Ahmad Radzaudin, Norfarihah
Ahmad Nadzirin, Izzuddin
author_facet Ahmad Radzaudin, Norfarihah
Ahmad Nadzirin, Izzuddin
author_sort Ahmad Radzaudin, Norfarihah
title Shingles remedies based on analysis of accordion-folded Malay medical manuscript MSS 3048
title_short Shingles remedies based on analysis of accordion-folded Malay medical manuscript MSS 3048
title_full Shingles remedies based on analysis of accordion-folded Malay medical manuscript MSS 3048
title_fullStr Shingles remedies based on analysis of accordion-folded Malay medical manuscript MSS 3048
title_full_unstemmed Shingles remedies based on analysis of accordion-folded Malay medical manuscript MSS 3048
title_sort shingles remedies based on analysis of accordion-folded malay medical manuscript mss 3048
publisher IIUM Press
publishDate 2024
url http://irep.iium.edu.my/115935/1/115935_Shingles%20remedies%20based%20on%20analysis%20of%20accordion-folded.pdf
http://irep.iium.edu.my/115935/
https://journals.iium.edu.my/ijahs/index.php/IJAHS/issue/view/36
_version_ 1817841051429240832
score 13.223943

Similar Items