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Nutrigenomics and Parkinson's disease

Parkinson’s disease (PD) is a multifactorial disease, the development, and progression of which are influenced by multiple factors, including the genetic markups and the environment. Nutrition is considered one of the most robust environmental factors affecting PD as it can either induce or reduce d...

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Main Authors: Razali, Khairiah, Algantri, Khaled, Loh, Su Peng, Cheng, Shi-Hui, Mohamed, Wael Mohamed Yousef
Format: Book Chapter
Language:English
Published: Elsevier 2024
Subjects:
R Medicine (General)
Online Access:http://irep.iium.edu.my/115365/13/115365_Nutrigenomics%20and%20Parkinson%27s%20disease.pdf
http://irep.iium.edu.my/115365/
https://www.sciencedirect.com/science/article/abs/pii/B978044315702800035X
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spelling my.iium.irep.1153652024-12-04T08:07:29Z http://irep.iium.edu.my/115365/ Nutrigenomics and Parkinson's disease Razali, Khairiah Algantri, Khaled Loh, Su Peng Cheng, Shi-Hui Mohamed, Wael Mohamed Yousef R Medicine (General) Parkinson’s disease (PD) is a multifactorial disease, the development, and progression of which are influenced by multiple factors, including the genetic markups and the environment. Nutrition is considered one of the most robust environmental factors affecting PD as it can either induce or reduce disease susceptibility. Epigenetic mechanisms regulate gene expression through DNA methylation, histone modifications, and noncoding RNAs (ncRNAs) activity. Accumulating evidence from nutriepigenomics studies has reported altered epigenetic mechanisms in clinical and preclinical PD models and the potential role of nutrition in modifying the changes. In addition, through nutrigenetics and nutrigenomics studies, the diet-gene, and gene-diet interactions in relation to PD development and progression have been investigated. Herein, current findings on the roles of nutrition in epigenetic mechanisms underpinning PD development and progression are discussed. Besides, the potential of the personalized nutrition approach as adjuvant therapy for PD are also underlined. Elsevier 2024-10-25 Book Chapter PeerReviewed application/pdf en http://irep.iium.edu.my/115365/13/115365_Nutrigenomics%20and%20Parkinson%27s%20disease.pdf Razali, Khairiah and Algantri, Khaled and Loh, Su Peng and Cheng, Shi-Hui and Mohamed, Wael Mohamed Yousef (2024) Nutrigenomics and Parkinson's disease. In: Essential Guide to Neurodegenerative Disorders: Mechanistic, Diagnostic and Therapeutic Advances. Elsevier, London, UK, pp. 605-629. ISBN 9780443157028 https://www.sciencedirect.com/science/article/abs/pii/B978044315702800035X 10.1016/B978-0-443-15702-8.00035-X
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic R Medicine (General)
spellingShingle R Medicine (General)
Razali, Khairiah
Algantri, Khaled
Loh, Su Peng
Cheng, Shi-Hui
Mohamed, Wael Mohamed Yousef
Nutrigenomics and Parkinson's disease
description Parkinson’s disease (PD) is a multifactorial disease, the development, and progression of which are influenced by multiple factors, including the genetic markups and the environment. Nutrition is considered one of the most robust environmental factors affecting PD as it can either induce or reduce disease susceptibility. Epigenetic mechanisms regulate gene expression through DNA methylation, histone modifications, and noncoding RNAs (ncRNAs) activity. Accumulating evidence from nutriepigenomics studies has reported altered epigenetic mechanisms in clinical and preclinical PD models and the potential role of nutrition in modifying the changes. In addition, through nutrigenetics and nutrigenomics studies, the diet-gene, and gene-diet interactions in relation to PD development and progression have been investigated. Herein, current findings on the roles of nutrition in epigenetic mechanisms underpinning PD development and progression are discussed. Besides, the potential of the personalized nutrition approach as adjuvant therapy for PD are also underlined.
format Book Chapter
author Razali, Khairiah
Algantri, Khaled
Loh, Su Peng
Cheng, Shi-Hui
Mohamed, Wael Mohamed Yousef
author_facet Razali, Khairiah
Algantri, Khaled
Loh, Su Peng
Cheng, Shi-Hui
Mohamed, Wael Mohamed Yousef
author_sort Razali, Khairiah
title Nutrigenomics and Parkinson's disease
title_short Nutrigenomics and Parkinson's disease
title_full Nutrigenomics and Parkinson's disease
title_fullStr Nutrigenomics and Parkinson's disease
title_full_unstemmed Nutrigenomics and Parkinson's disease
title_sort nutrigenomics and parkinson's disease
publisher Elsevier
publishDate 2024
url http://irep.iium.edu.my/115365/13/115365_Nutrigenomics%20and%20Parkinson%27s%20disease.pdf
http://irep.iium.edu.my/115365/
https://www.sciencedirect.com/science/article/abs/pii/B978044315702800035X
_version_ 1817841071292416000
score 13.223943

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