Revisiting essential hypertension, regulation of blood pressure control and the Adrenaline Hypothesis

Hypertension or high blood pressure (BP) is a condition that has a significant impact on the world's population morbidity and mortality. The World Health Report 2002, stated that high blood pressure caused 7.1 million deaths throughout the world, which was approximately 13% of total deaths wo...

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Main Authors: Abdullah, Aszrin, Mohd Shah, Azarisman Shah, Mohd Noor, Noriah, Abdul Razak, Tariq
Format: Article
Language:English
Published: IIUM 2015
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Online Access:http://irep.iium.edu.my/110983/2/110983_Revisiting%20essential%20hypertension.pdf
http://irep.iium.edu.my/110983/
https://journals.iium.edu.my/kom/index.php/imjm/article/view/1406
https://doi.org/10.31436/imjm.v14i1.1406
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spelling my.iium.irep.1109832024-02-23T03:45:14Z http://irep.iium.edu.my/110983/ Revisiting essential hypertension, regulation of blood pressure control and the Adrenaline Hypothesis Abdullah, Aszrin Mohd Shah, Azarisman Shah Mohd Noor, Noriah Abdul Razak, Tariq QP Physiology R Medicine (General) RC Internal medicine Hypertension or high blood pressure (BP) is a condition that has a significant impact on the world's population morbidity and mortality. The World Health Report 2002, stated that high blood pressure caused 7.1 million deaths throughout the world, which was approximately 13% of total deaths worldwide. The body's arterial blood pressure control depends on short-term and long-term mechanisms. Short-term BP regulation is mediated by the autonomic nervous system (ANS) targeting the heart, vessels, and adrenal medulla. The sympathetic nervous systems (SNS) crucial involvement in stressful conditions and short term regulation of blood pressure is also widely accepted. There has also been increasing evidence and recognition of sympathetic augmentation as the main cause for essential hypertension in a significant number of patients especially those with no known attributable secondary causes and those who are young. We discuss the role of the adrenaline hypothesis in the pathophysiology of hypertension. IIUM 2015-12 Article PeerReviewed application/pdf en http://irep.iium.edu.my/110983/2/110983_Revisiting%20essential%20hypertension.pdf Abdullah, Aszrin and Mohd Shah, Azarisman Shah and Mohd Noor, Noriah and Abdul Razak, Tariq (2015) Revisiting essential hypertension, regulation of blood pressure control and the Adrenaline Hypothesis. International Medical Journal Malaysia, 14 (Suppliment Issue). pp. 8-9. ISSN 1823-4631 E-ISSN 2735-2285 https://journals.iium.edu.my/kom/index.php/imjm/article/view/1406 https://doi.org/10.31436/imjm.v14i1.1406
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic QP Physiology
R Medicine (General)
RC Internal medicine
spellingShingle QP Physiology
R Medicine (General)
RC Internal medicine
Abdullah, Aszrin
Mohd Shah, Azarisman Shah
Mohd Noor, Noriah
Abdul Razak, Tariq
Revisiting essential hypertension, regulation of blood pressure control and the Adrenaline Hypothesis
description Hypertension or high blood pressure (BP) is a condition that has a significant impact on the world's population morbidity and mortality. The World Health Report 2002, stated that high blood pressure caused 7.1 million deaths throughout the world, which was approximately 13% of total deaths worldwide. The body's arterial blood pressure control depends on short-term and long-term mechanisms. Short-term BP regulation is mediated by the autonomic nervous system (ANS) targeting the heart, vessels, and adrenal medulla. The sympathetic nervous systems (SNS) crucial involvement in stressful conditions and short term regulation of blood pressure is also widely accepted. There has also been increasing evidence and recognition of sympathetic augmentation as the main cause for essential hypertension in a significant number of patients especially those with no known attributable secondary causes and those who are young. We discuss the role of the adrenaline hypothesis in the pathophysiology of hypertension.
format Article
author Abdullah, Aszrin
Mohd Shah, Azarisman Shah
Mohd Noor, Noriah
Abdul Razak, Tariq
author_facet Abdullah, Aszrin
Mohd Shah, Azarisman Shah
Mohd Noor, Noriah
Abdul Razak, Tariq
author_sort Abdullah, Aszrin
title Revisiting essential hypertension, regulation of blood pressure control and the Adrenaline Hypothesis
title_short Revisiting essential hypertension, regulation of blood pressure control and the Adrenaline Hypothesis
title_full Revisiting essential hypertension, regulation of blood pressure control and the Adrenaline Hypothesis
title_fullStr Revisiting essential hypertension, regulation of blood pressure control and the Adrenaline Hypothesis
title_full_unstemmed Revisiting essential hypertension, regulation of blood pressure control and the Adrenaline Hypothesis
title_sort revisiting essential hypertension, regulation of blood pressure control and the adrenaline hypothesis
publisher IIUM
publishDate 2015
url http://irep.iium.edu.my/110983/2/110983_Revisiting%20essential%20hypertension.pdf
http://irep.iium.edu.my/110983/
https://journals.iium.edu.my/kom/index.php/imjm/article/view/1406
https://doi.org/10.31436/imjm.v14i1.1406
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