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The AfrAbia+plus Parkinson's disease genomic consortium

Many human studies, including those involving genetics, are conducted in people of northern European ancestry. A lack of ancestral representation in genetics makes it harder to understand the underlying biology of disease, results in unsupported generalisation of current genetics to under-represente...

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Main Authors: Mohamed, Wael Mohamed Yousef, Eltantawi, Mohamed Abdelhalim, Mecheri, Yasser, Zewde, Yared Zenebe, Kamel, Walaa A, Al-Mubarak, Bashayer R, Alzoubi, Karem H
Format: Article
Language:English
Published: Elsevier 2024
Subjects:
R Medicine (General)
Online Access:http://irep.iium.edu.my/110532/1/110532_THE%20AFRABIA%20%2B%20PLUS%20PARKINSON%27S%20DISEASE%20GENOMIC.pdf
http://irep.iium.edu.my/110532/
https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00453-2/fulltext#%20
https://doi.org/10.1016/S1474-4422(23)00453-2
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spelling my.iium.irep.1105322024-07-29T03:16:11Z http://irep.iium.edu.my/110532/ The AfrAbia+plus Parkinson's disease genomic consortium Mohamed, Wael Mohamed Yousef Eltantawi, Mohamed Abdelhalim Mecheri, Yasser Zewde, Yared Zenebe Kamel, Walaa A Al-Mubarak, Bashayer R Alzoubi, Karem H R Medicine (General) Many human studies, including those involving genetics, are conducted in people of northern European ancestry. A lack of ancestral representation in genetics makes it harder to understand the underlying biology of disease, results in unsupported generalisation of current genetics to under-represented groups, limits our capacity to deploy precision therapeutics to only those populations that have been studied, and prevents us from accurately mapping genetic loci. Studies in Parkinson's disease have experienced a similar lack of diversity. The Global Parkinson's Genetics Program (GP2) was initiated in 2020 to meet this need for diversity in research. GP2 seeks to improve understanding of the genetic architecture of Parkinson's disease in a global context. A result of this work was the establishment of the AfrAbia Parkinson's Disease Genomic Consortium (AA-PDGC) in 2023. Elsevier 2024-01-23 Article PeerReviewed application/pdf en http://irep.iium.edu.my/110532/1/110532_THE%20AFRABIA%20%2B%20PLUS%20PARKINSON%27S%20DISEASE%20GENOMIC.pdf Mohamed, Wael Mohamed Yousef and Eltantawi, Mohamed Abdelhalim and Mecheri, Yasser and Zewde, Yared Zenebe and Kamel, Walaa A and Al-Mubarak, Bashayer R and Alzoubi, Karem H (2024) The AfrAbia+plus Parkinson's disease genomic consortium. The Lancet Neurology, Vol 23. pp. 140-141. ISSN 1474-4422 E-ISSN 1474-4465 https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00453-2/fulltext#%20 https://doi.org/10.1016/S1474-4422(23)00453-2
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic R Medicine (General)
spellingShingle R Medicine (General)
Mohamed, Wael Mohamed Yousef
Eltantawi, Mohamed Abdelhalim
Mecheri, Yasser
Zewde, Yared Zenebe
Kamel, Walaa A
Al-Mubarak, Bashayer R
Alzoubi, Karem H
The AfrAbia+plus Parkinson's disease genomic consortium
description Many human studies, including those involving genetics, are conducted in people of northern European ancestry. A lack of ancestral representation in genetics makes it harder to understand the underlying biology of disease, results in unsupported generalisation of current genetics to under-represented groups, limits our capacity to deploy precision therapeutics to only those populations that have been studied, and prevents us from accurately mapping genetic loci. Studies in Parkinson's disease have experienced a similar lack of diversity. The Global Parkinson's Genetics Program (GP2) was initiated in 2020 to meet this need for diversity in research. GP2 seeks to improve understanding of the genetic architecture of Parkinson's disease in a global context. A result of this work was the establishment of the AfrAbia Parkinson's Disease Genomic Consortium (AA-PDGC) in 2023.
format Article
author Mohamed, Wael Mohamed Yousef
Eltantawi, Mohamed Abdelhalim
Mecheri, Yasser
Zewde, Yared Zenebe
Kamel, Walaa A
Al-Mubarak, Bashayer R
Alzoubi, Karem H
author_facet Mohamed, Wael Mohamed Yousef
Eltantawi, Mohamed Abdelhalim
Mecheri, Yasser
Zewde, Yared Zenebe
Kamel, Walaa A
Al-Mubarak, Bashayer R
Alzoubi, Karem H
author_sort Mohamed, Wael Mohamed Yousef
title The AfrAbia+plus Parkinson's disease genomic consortium
title_short The AfrAbia+plus Parkinson's disease genomic consortium
title_full The AfrAbia+plus Parkinson's disease genomic consortium
title_fullStr The AfrAbia+plus Parkinson's disease genomic consortium
title_full_unstemmed The AfrAbia+plus Parkinson's disease genomic consortium
title_sort afrabia+plus parkinson's disease genomic consortium
publisher Elsevier
publishDate 2024
url http://irep.iium.edu.my/110532/1/110532_THE%20AFRABIA%20%2B%20PLUS%20PARKINSON%27S%20DISEASE%20GENOMIC.pdf
http://irep.iium.edu.my/110532/
https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00453-2/fulltext#%20
https://doi.org/10.1016/S1474-4422(23)00453-2
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score 13.211869

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