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The relationship of vitamin B6 (pyridoxin) and postpartum depression: a scoping review

Introduction: Postpartum depression (PPD) is one of the mental disorders that has a negative impact on a mother’s feelings after birth and causes them to lose interest in living their daily lives, primarily due to the chemical imbalance in the brain. Vitamin B6, or known as pyridoxine, is believed t...

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Main Authors: Abdul Ghani, Radiah, Ahmad Yusof, Nuraqilah Humaira
Format: Article
Language:English
Published: IIUM Press, International Islamic University Malaysia 2023
Subjects:
RM216 Diet Therapy. Clinical Nutrition
Online Access:http://irep.iium.edu.my/108746/7/108746_The%20relationship%20of%20vitamin%20B6%20%28pyridoxin%29%20and%20postpartum%20depression.pdf
http://irep.iium.edu.my/108746/
https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/875
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spelling my.iium.irep.1087462024-02-27T02:20:19Z http://irep.iium.edu.my/108746/ The relationship of vitamin B6 (pyridoxin) and postpartum depression: a scoping review Abdul Ghani, Radiah Ahmad Yusof, Nuraqilah Humaira RM216 Diet Therapy. Clinical Nutrition Introduction: Postpartum depression (PPD) is one of the mental disorders that has a negative impact on a mother’s feelings after birth and causes them to lose interest in living their daily lives, primarily due to the chemical imbalance in the brain. Vitamin B6, or known as pyridoxine, is believed to be one of the chemicals in the brain which is involved in emotional regulation. However, the mechanism of action is unknown. Thus, the aim of this study is to review the influence of vitamin B6 and its relationship with the onset of PPD. Methods: Keywords "vitamin B6" and "vitamin B" and "pyridoxine" and "nutrition" and "PPD" and “perinatal depression” were employed in PubMed, SpringerLink, BioMed Central Journal and ScienceDirect. The screened articles were chosen based on their suitability for the topic of interest and published in English between 2000 and2023. The articles were chosen in accordance with PRISMA, and their eligibility was determined using inclusion and exclusion criteria. Results: A total of 3404 articles had been obtained initially and the resulting five articles met the criteria. It was revealed that the relationship between deficiency of vitamin B6 and PPD is still ambiguous. Two articles suggested the intake of vitamin B6 to an adequate level can be helpful to reduce the risk of PPD. In contrast, there are three studies that proposed that low vitamin B6 levels are not associated with PPD, hence increasing its intake during this period is found to be irrelevant. Conclusion: In conclusion, this review indicates that further investigation is warranted to determine the exact effect of vitamin B6 and its mechanism of action in emotional regulation. It is hoped that this benefits the mothers in prevention and treatment of PPD, thus improving the quality of their life. IIUM Press, International Islamic University Malaysia 2023-12-08 Article PeerReviewed application/pdf en http://irep.iium.edu.my/108746/7/108746_The%20relationship%20of%20vitamin%20B6%20%28pyridoxin%29%20and%20postpartum%20depression.pdf Abdul Ghani, Radiah and Ahmad Yusof, Nuraqilah Humaira (2023) The relationship of vitamin B6 (pyridoxin) and postpartum depression: a scoping review. International Journal of Allied Health Sciences (IJAHS), 7 (5). pp. 475-483. E-ISSN 2600-8491 https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/875
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
topic RM216 Diet Therapy. Clinical Nutrition
spellingShingle RM216 Diet Therapy. Clinical Nutrition
Abdul Ghani, Radiah
Ahmad Yusof, Nuraqilah Humaira
The relationship of vitamin B6 (pyridoxin) and postpartum depression: a scoping review
description Introduction: Postpartum depression (PPD) is one of the mental disorders that has a negative impact on a mother’s feelings after birth and causes them to lose interest in living their daily lives, primarily due to the chemical imbalance in the brain. Vitamin B6, or known as pyridoxine, is believed to be one of the chemicals in the brain which is involved in emotional regulation. However, the mechanism of action is unknown. Thus, the aim of this study is to review the influence of vitamin B6 and its relationship with the onset of PPD. Methods: Keywords "vitamin B6" and "vitamin B" and "pyridoxine" and "nutrition" and "PPD" and “perinatal depression” were employed in PubMed, SpringerLink, BioMed Central Journal and ScienceDirect. The screened articles were chosen based on their suitability for the topic of interest and published in English between 2000 and2023. The articles were chosen in accordance with PRISMA, and their eligibility was determined using inclusion and exclusion criteria. Results: A total of 3404 articles had been obtained initially and the resulting five articles met the criteria. It was revealed that the relationship between deficiency of vitamin B6 and PPD is still ambiguous. Two articles suggested the intake of vitamin B6 to an adequate level can be helpful to reduce the risk of PPD. In contrast, there are three studies that proposed that low vitamin B6 levels are not associated with PPD, hence increasing its intake during this period is found to be irrelevant. Conclusion: In conclusion, this review indicates that further investigation is warranted to determine the exact effect of vitamin B6 and its mechanism of action in emotional regulation. It is hoped that this benefits the mothers in prevention and treatment of PPD, thus improving the quality of their life.
format Article
author Abdul Ghani, Radiah
Ahmad Yusof, Nuraqilah Humaira
author_facet Abdul Ghani, Radiah
Ahmad Yusof, Nuraqilah Humaira
author_sort Abdul Ghani, Radiah
title The relationship of vitamin B6 (pyridoxin) and postpartum depression: a scoping review
title_short The relationship of vitamin B6 (pyridoxin) and postpartum depression: a scoping review
title_full The relationship of vitamin B6 (pyridoxin) and postpartum depression: a scoping review
title_fullStr The relationship of vitamin B6 (pyridoxin) and postpartum depression: a scoping review
title_full_unstemmed The relationship of vitamin B6 (pyridoxin) and postpartum depression: a scoping review
title_sort relationship of vitamin b6 (pyridoxin) and postpartum depression: a scoping review
publisher IIUM Press, International Islamic University Malaysia
publishDate 2023
url http://irep.iium.edu.my/108746/7/108746_The%20relationship%20of%20vitamin%20B6%20%28pyridoxin%29%20and%20postpartum%20depression.pdf
http://irep.iium.edu.my/108746/
https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/875
_version_ 1792146421030322176
score 13.211869

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