Staff View: Tongkat ali root extract helps promote good oral health

Tongkat ali root extract helps promote good oral health

Introduction: One of the important issues in oral healthcare is prevention of dental caries through maintenance of good oral hygiene. Despite the availability of many products in the market, dental caries and oral health problems still occur at high prevalence. Thus the introduction of natural remed...

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Main Authors:	Ramzi, Muhamad Iyad, Kosnin, Muhammad Hazzim, Faisal, Ghasak Ghazi, Arzmi, Mohd Hafiz, Kusumawardani, Anisa
Format:	Proceeding Paper
Language:	English English English English
Published:	2023
Subjects:	RK Dentistry RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works
Online Access:	http://irep.iium.edu.my/107931/1/GHASAK-IIUM-POSTER-WITHOUTVIDEO%20-%20Copy.pdf http://irep.iium.edu.my/107931/3/NOHRI%20Book%20Final.pdf http://irep.iium.edu.my/107931/2/E-Poster%20Presentation%20%28Senior%20Researcher%20Category%29-1-2.pdf http://irep.iium.edu.my/107931/19/107931_Tongkat%20ali%20root%20extract%20helps%20promote%20good%20oral%20health.pdf http://irep.iium.edu.my/107931/ https://conference.iium.edu.my/nohri2023/index.php/about-nohri-2/
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spelling	my.iium.irep.1079312023-11-14T04:04:59Z http://irep.iium.edu.my/107931/ Tongkat ali root extract helps promote good oral health Ramzi, Muhamad Iyad Kosnin, Muhammad Hazzim Faisal, Ghasak Ghazi Arzmi, Mohd Hafiz Kusumawardani, Anisa RK Dentistry RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works Introduction: One of the important issues in oral healthcare is prevention of dental caries through maintenance of good oral hygiene. Despite the availability of many products in the market, dental caries and oral health problems still occur at high prevalence. Thus the introduction of natural remedies that can help promote oral health is of great importance. Eurycoma Longifolia Jack or Tongkat Ali roots have been known for a diverse spectrum of medicinal properties, one of which is antimicrobial activity. Thus our objectives were to test the activity of the root extract against important oral bacteria and fungi that are responsible for causing dental caries and other oral conditions. The roots of E. longifolia or Tongkat Ali have been used to in traditional medicine as well as supplements and food additives. Many chemical compounds have been detected in extracts of its roots which is believed to be responsible for its medicinal properties. In this study, our objectives were to study the effect of the E. Longifolia root extracts on the growth of Streptococcus Mutans, Lactobacillus and Candida Albicans isolated from saliva of adult patients with high caries risk. Materials and methods: The ethanolic extract of the root of this plant was tested against saliva isolated Streptococcus Mutans, Lactobacillus and Candida Albicans via disc diffusion assay at a concentration of 200mg/mL. The minimum inhibitory concentration was carried out by the standard broth microdilution method. Cell viability of test microorganisms against different concentration of the extract and inhibition zones were calculated. Results: Disk diffusion assay showed positive zones of inhibition for all test microorganisms with S. mutans, Lactobacillus and C. albicans exhibiting zones of inhibition of 8.3 ± 0.7mm, 12.4 ± 2.4mm and 21.4 ± 2.7mm respectively. For minimum inhibitory concentration, the test microorganisms were tested at concentration of 250mg/mL, 125mg/mL, 62.5mg/mL, 31.3mg/mL and 0mg/mL.The minimum inhibitory concentration showed that MIC of S. mutans was at 62.5mg/mL, Lactobacillus at 125mg/mL and C. albicans at 31.3mg/mL. Lastly, the cell viability results supports the MIC determined prior. Conclusion: Ethanol-based E. longifolia Jack root extract has an antimicrobial effect on the following microorganisms isolated from the saliva of high risk caries adult patients: S. mutans, Lactobacillus and C. albicans. 2023-10-20 Proceeding Paper NonPeerReviewed application/pdf en http://irep.iium.edu.my/107931/1/GHASAK-IIUM-POSTER-WITHOUTVIDEO%20-%20Copy.pdf application/pdf en http://irep.iium.edu.my/107931/3/NOHRI%20Book%20Final.pdf application/pdf en http://irep.iium.edu.my/107931/2/E-Poster%20Presentation%20%28Senior%20Researcher%20Category%29-1-2.pdf application/pdf en http://irep.iium.edu.my/107931/19/107931_Tongkat%20ali%20root%20extract%20helps%20promote%20good%20oral%20health.pdf Ramzi, Muhamad Iyad and Kosnin, Muhammad Hazzim and Faisal, Ghasak Ghazi and Arzmi, Mohd Hafiz and Kusumawardani, Anisa (2023) Tongkat ali root extract helps promote good oral health. In: IIUM National Oral Health Research Initiative (NOHRI) Conference 2023, 20-21 Oct 2023, Kuantan, Malaysia. (Unpublished) https://conference.iium.edu.my/nohri2023/index.php/about-nohri-2/
institution	Universiti Islam Antarabangsa Malaysia
building	IIUM Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	International Islamic University Malaysia
content_source	IIUM Repository (IREP)
url_provider	http://irep.iium.edu.my/
language	English English English English
topic	RK Dentistry RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works
spellingShingle	RK Dentistry RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works Ramzi, Muhamad Iyad Kosnin, Muhammad Hazzim Faisal, Ghasak Ghazi Arzmi, Mohd Hafiz Kusumawardani, Anisa Tongkat ali root extract helps promote good oral health
description	Introduction: One of the important issues in oral healthcare is prevention of dental caries through maintenance of good oral hygiene. Despite the availability of many products in the market, dental caries and oral health problems still occur at high prevalence. Thus the introduction of natural remedies that can help promote oral health is of great importance. Eurycoma Longifolia Jack or Tongkat Ali roots have been known for a diverse spectrum of medicinal properties, one of which is antimicrobial activity. Thus our objectives were to test the activity of the root extract against important oral bacteria and fungi that are responsible for causing dental caries and other oral conditions. The roots of E. longifolia or Tongkat Ali have been used to in traditional medicine as well as supplements and food additives. Many chemical compounds have been detected in extracts of its roots which is believed to be responsible for its medicinal properties. In this study, our objectives were to study the effect of the E. Longifolia root extracts on the growth of Streptococcus Mutans, Lactobacillus and Candida Albicans isolated from saliva of adult patients with high caries risk. Materials and methods: The ethanolic extract of the root of this plant was tested against saliva isolated Streptococcus Mutans, Lactobacillus and Candida Albicans via disc diffusion assay at a concentration of 200mg/mL. The minimum inhibitory concentration was carried out by the standard broth microdilution method. Cell viability of test microorganisms against different concentration of the extract and inhibition zones were calculated. Results: Disk diffusion assay showed positive zones of inhibition for all test microorganisms with S. mutans, Lactobacillus and C. albicans exhibiting zones of inhibition of 8.3 ± 0.7mm, 12.4 ± 2.4mm and 21.4 ± 2.7mm respectively. For minimum inhibitory concentration, the test microorganisms were tested at concentration of 250mg/mL, 125mg/mL, 62.5mg/mL, 31.3mg/mL and 0mg/mL.The minimum inhibitory concentration showed that MIC of S. mutans was at 62.5mg/mL, Lactobacillus at 125mg/mL and C. albicans at 31.3mg/mL. Lastly, the cell viability results supports the MIC determined prior. Conclusion: Ethanol-based E. longifolia Jack root extract has an antimicrobial effect on the following microorganisms isolated from the saliva of high risk caries adult patients: S. mutans, Lactobacillus and C. albicans.
format	Proceeding Paper
author	Ramzi, Muhamad Iyad Kosnin, Muhammad Hazzim Faisal, Ghasak Ghazi Arzmi, Mohd Hafiz Kusumawardani, Anisa
author_facet	Ramzi, Muhamad Iyad Kosnin, Muhammad Hazzim Faisal, Ghasak Ghazi Arzmi, Mohd Hafiz Kusumawardani, Anisa
author_sort	Ramzi, Muhamad Iyad
title	Tongkat ali root extract helps promote good oral health
title_short	Tongkat ali root extract helps promote good oral health
title_full	Tongkat ali root extract helps promote good oral health
title_fullStr	Tongkat ali root extract helps promote good oral health
title_full_unstemmed	Tongkat ali root extract helps promote good oral health
title_sort	tongkat ali root extract helps promote good oral health
publishDate	2023
url	http://irep.iium.edu.my/107931/1/GHASAK-IIUM-POSTER-WITHOUTVIDEO%20-%20Copy.pdf http://irep.iium.edu.my/107931/3/NOHRI%20Book%20Final.pdf http://irep.iium.edu.my/107931/2/E-Poster%20Presentation%20%28Senior%20Researcher%20Category%29-1-2.pdf http://irep.iium.edu.my/107931/19/107931_Tongkat%20ali%20root%20extract%20helps%20promote%20good%20oral%20health.pdf http://irep.iium.edu.my/107931/ https://conference.iium.edu.my/nohri2023/index.php/about-nohri-2/
_version_	1783876104619032576
score	13.211869

Tongkat ali root extract helps promote good oral health

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