Evaluation of occupational exposure to TiO2 nanoparticles: microwave-assisted acid digestion method on air membrane filters

Titanium dioxide (TiO2) nanoparticles have been extensively used in various industrial sectors and applications, including cosmetics, catalysts, food additives, inks, paints, and coatings. However, the International Agency for Research on Cancer (IARC) has classified TiO2 nanoparticles as a potent...

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Main Authors: Jamen, Shahrulnizam, Mohd Aris, Mohd Shukri, Shamsul Harumain, Zakuan Azizi, Zahaba, Maryam, Danial, Wan Hazman, Abdul Hadi, Hazrin
Format: Article
Language:English
English
Published: Faculty of Medicine, Universiti Malaya 2023
Subjects:
Online Access:http://irep.iium.edu.my/107178/1/107178_Evaluation%20of%20occupational.pdf
http://irep.iium.edu.my/107178/7/107178_Evaluation%20of%20occupational_SCOPUS.pdf
http://irep.iium.edu.my/107178/
https://jummec.um.edu.my/index.php/jummec/article/view/45021
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spelling my.iium.irep.1071782024-03-11T02:45:03Z http://irep.iium.edu.my/107178/ Evaluation of occupational exposure to TiO2 nanoparticles: microwave-assisted acid digestion method on air membrane filters Jamen, Shahrulnizam Mohd Aris, Mohd Shukri Shamsul Harumain, Zakuan Azizi Zahaba, Maryam Danial, Wan Hazman Abdul Hadi, Hazrin Q Science (General) Titanium dioxide (TiO2) nanoparticles have been extensively used in various industrial sectors and applications, including cosmetics, catalysts, food additives, inks, paints, and coatings. However, the International Agency for Research on Cancer (IARC) has classified TiO2 nanoparticles as a potential carcinogen for humans, meaning they may cause cancer and pose serious health complications, particularly for manufacturing workers. This highlights the need for better evaluation to determine worker exposure. In this study, suspended TiO2 nanoparticles were sampled using a nanoparticle respiratory deposition (NRD) sampler fitted with specially designed membrane filters and analyzed using Inductively Coupled Plasma Mass Spectrometry (ICP-MS). The digestion method used for titanium element recovery after nanoparticle sampling is crucial for optimal ICP-MS analysis. Therefore, this study aimed to investigate the most suitable digestion method. A microwave-acid digestion method using concentrated nitric acid and concentrated hydrochloric acid at a 7:4 ratio, with a run time of 30 minutes and the temperature set to 200°C showed remarkable titanium recovery compared to other methods. These findings may pave the way for optimal analysis of suspended TiO2 nanoparticles in assessing occupational exposure while promoting sustainability and eco-friendliness in resource utilization. Faculty of Medicine, Universiti Malaya 2023-09-26 Article PeerReviewed application/pdf en http://irep.iium.edu.my/107178/1/107178_Evaluation%20of%20occupational.pdf application/pdf en http://irep.iium.edu.my/107178/7/107178_Evaluation%20of%20occupational_SCOPUS.pdf Jamen, Shahrulnizam and Mohd Aris, Mohd Shukri and Shamsul Harumain, Zakuan Azizi and Zahaba, Maryam and Danial, Wan Hazman and Abdul Hadi, Hazrin (2023) Evaluation of occupational exposure to TiO2 nanoparticles: microwave-assisted acid digestion method on air membrane filters. Journal of Health and Translational Medicine (Special Issue 2). pp. 353-357. ISSN 1823-7339 E-ISSN 2289-392X https://jummec.um.edu.my/index.php/jummec/article/view/45021 10.22452/jummec.sp2023no2.39
institution Universiti Islam Antarabangsa Malaysia
building IIUM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider International Islamic University Malaysia
content_source IIUM Repository (IREP)
url_provider http://irep.iium.edu.my/
language English
English
topic Q Science (General)
spellingShingle Q Science (General)
Jamen, Shahrulnizam
Mohd Aris, Mohd Shukri
Shamsul Harumain, Zakuan Azizi
Zahaba, Maryam
Danial, Wan Hazman
Abdul Hadi, Hazrin
Evaluation of occupational exposure to TiO2 nanoparticles: microwave-assisted acid digestion method on air membrane filters
description Titanium dioxide (TiO2) nanoparticles have been extensively used in various industrial sectors and applications, including cosmetics, catalysts, food additives, inks, paints, and coatings. However, the International Agency for Research on Cancer (IARC) has classified TiO2 nanoparticles as a potential carcinogen for humans, meaning they may cause cancer and pose serious health complications, particularly for manufacturing workers. This highlights the need for better evaluation to determine worker exposure. In this study, suspended TiO2 nanoparticles were sampled using a nanoparticle respiratory deposition (NRD) sampler fitted with specially designed membrane filters and analyzed using Inductively Coupled Plasma Mass Spectrometry (ICP-MS). The digestion method used for titanium element recovery after nanoparticle sampling is crucial for optimal ICP-MS analysis. Therefore, this study aimed to investigate the most suitable digestion method. A microwave-acid digestion method using concentrated nitric acid and concentrated hydrochloric acid at a 7:4 ratio, with a run time of 30 minutes and the temperature set to 200°C showed remarkable titanium recovery compared to other methods. These findings may pave the way for optimal analysis of suspended TiO2 nanoparticles in assessing occupational exposure while promoting sustainability and eco-friendliness in resource utilization.
format Article
author Jamen, Shahrulnizam
Mohd Aris, Mohd Shukri
Shamsul Harumain, Zakuan Azizi
Zahaba, Maryam
Danial, Wan Hazman
Abdul Hadi, Hazrin
author_facet Jamen, Shahrulnizam
Mohd Aris, Mohd Shukri
Shamsul Harumain, Zakuan Azizi
Zahaba, Maryam
Danial, Wan Hazman
Abdul Hadi, Hazrin
author_sort Jamen, Shahrulnizam
title Evaluation of occupational exposure to TiO2 nanoparticles: microwave-assisted acid digestion method on air membrane filters
title_short Evaluation of occupational exposure to TiO2 nanoparticles: microwave-assisted acid digestion method on air membrane filters
title_full Evaluation of occupational exposure to TiO2 nanoparticles: microwave-assisted acid digestion method on air membrane filters
title_fullStr Evaluation of occupational exposure to TiO2 nanoparticles: microwave-assisted acid digestion method on air membrane filters
title_full_unstemmed Evaluation of occupational exposure to TiO2 nanoparticles: microwave-assisted acid digestion method on air membrane filters
title_sort evaluation of occupational exposure to tio2 nanoparticles: microwave-assisted acid digestion method on air membrane filters
publisher Faculty of Medicine, Universiti Malaya
publishDate 2023
url http://irep.iium.edu.my/107178/1/107178_Evaluation%20of%20occupational.pdf
http://irep.iium.edu.my/107178/7/107178_Evaluation%20of%20occupational_SCOPUS.pdf
http://irep.iium.edu.my/107178/
https://jummec.um.edu.my/index.php/jummec/article/view/45021
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score 13.211869