Evaluation of occupational exposure to TiO2 nanoparticles: microwave-assisted acid digestion method on air membrane filters

Titanium dioxide (TiO2) nanoparticles have been extensively used in various industrial sectors and applications, including cosmetics, catalysts, food additives, inks, paints, and coatings. However, the International Agency for Research on Cancer (IARC) has classified TiO2 nanoparticles as a potent...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Jamen, Shahrulnizam, Mohd Aris, Mohd Shukri, Shamsul Harumain, Zakuan Azizi, Zahaba, Maryam, Danial, Wan Hazman, Abdul Hadi, Hazrin
التنسيق: مقال
اللغة:English
English
منشور في: Faculty of Medicine, Universiti Malaya 2023
الموضوعات:
الوصول للمادة أونلاين:http://irep.iium.edu.my/107178/1/107178_Evaluation%20of%20occupational.pdf
http://irep.iium.edu.my/107178/7/107178_Evaluation%20of%20occupational_SCOPUS.pdf
http://irep.iium.edu.my/107178/
https://jummec.um.edu.my/index.php/jummec/article/view/45021
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الوصف
الملخص:Titanium dioxide (TiO2) nanoparticles have been extensively used in various industrial sectors and applications, including cosmetics, catalysts, food additives, inks, paints, and coatings. However, the International Agency for Research on Cancer (IARC) has classified TiO2 nanoparticles as a potential carcinogen for humans, meaning they may cause cancer and pose serious health complications, particularly for manufacturing workers. This highlights the need for better evaluation to determine worker exposure. In this study, suspended TiO2 nanoparticles were sampled using a nanoparticle respiratory deposition (NRD) sampler fitted with specially designed membrane filters and analyzed using Inductively Coupled Plasma Mass Spectrometry (ICP-MS). The digestion method used for titanium element recovery after nanoparticle sampling is crucial for optimal ICP-MS analysis. Therefore, this study aimed to investigate the most suitable digestion method. A microwave-acid digestion method using concentrated nitric acid and concentrated hydrochloric acid at a 7:4 ratio, with a run time of 30 minutes and the temperature set to 200°C showed remarkable titanium recovery compared to other methods. These findings may pave the way for optimal analysis of suspended TiO2 nanoparticles in assessing occupational exposure while promoting sustainability and eco-friendliness in resource utilization.